Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells
出版年份 2013 全文链接
标题
Targeting cell migration and the endoplasmic reticulum stress response with calmodulin antagonists: a clinically tested small molecule phenocopy of SEC62 gene silencing in human tumor cells
作者
关键词
Endoplasmic reticulum (ER) stress, Cell migration, Ca<sup>2+</sup> homeostasis, Calmodulin antagonists, Sec62
出版物
BMC CANCER
Volume 13, Issue 1, Pages -
出版商
Springer Nature
发表日期
2013-12-05
DOI
10.1186/1471-2407-13-574
参考文献
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- (2012) S. Christensen et al. Anti-Cancer Agents in Medicinal Chemistry
- BiP-mediated closing of the Sec61 channel limits Ca2+leakage from the ER
- (2012) Nico Schäuble et al. EMBO JOURNAL
- Different effects of Sec61 , Sec62 and Sec63 depletion on transport of polypeptides into the endoplasmic reticulum of mammalian cells
- (2012) S. Lang et al. JOURNAL OF CELL SCIENCE
- Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation
- (2012) Asvin K. K. Lakkaraju et al. MOLECULAR BIOLOGY OF THE CELL
- Another view of the history of antipsychotic drug discovery and development
- (2012) W T Carpenter et al. MOLECULAR PSYCHIATRY
- Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
- (2012) S. R. Denmeade et al. Science Translational Medicine
- Sec62 Bridges the Gap from 3q Amplification to Molecular Cell Biology in Non–Small Cell Lung Cancer
- (2011) Maximilian Linxweiler et al. AMERICAN JOURNAL OF PATHOLOGY
- Calmodulin regulation of the calcium-leak channel Sec61 is unique to vertebrates
- (2011) Anke Harsman et al. Channels
- Calmodulin Mediates Fas-induced FADD-independent Survival Signaling in Pancreatic Cancer Cells via Activation of Src-Extracellular Signal-regulated Kinase (ERK)
- (2011) Kaiyu Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- RNAi momentum fizzles as pharma shifts priorities
- (2011) Charles Schmidt NATURE BIOTECHNOLOGY
- Sec62 protein level is crucial for the ER stress tolerance of prostate cancer
- (2011) Markus Greiner et al. PROSTATE
- Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Cα-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated kinase/activat
- (2010) Yong P Hwang et al. BRITISH JOURNAL OF PHARMACOLOGY
- A role for protein kinase C in the regulation of membrane fluidity and Ca2+ flux at the endoplasmic reticulum and plasma membranes of HEK293 and Jurkat cells
- (2010) Lihong Chen et al. CELLULAR SIGNALLING
- What made sesquiterpene lactones reach cancer clinical trials?
- (2010) Akram Ghantous et al. DRUG DISCOVERY TODAY
- Interaction of calmodulin with Sec61α limits Ca2+leakage from the endoplasmic reticulum
- (2010) Frank Erdmann et al. EMBO JOURNAL
- Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells
- (2010) Markus Greiner et al. INTERNATIONAL JOURNAL OF CANCER
- Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
- (2010) Jacques Ferlay et al. INTERNATIONAL JOURNAL OF CANCER
- A Novel Ca2+/Calmodulin Antagonist HBC Inhibits Angiogenesis and Down-regulates Hypoxia-inducible Factor
- (2010) Hye Jin Jung et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- 12-O-tetradecanoylphorbol-13-acetate-induced invasion/migration of glioblastoma cells through activating PKCα/ERK/NF-κB-dependent MMP-9 expression
- (2010) Cheng-Wei Lin et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Evolutionary Gain of Function for the ER Membrane Protein Sec62 from Yeast to Humans
- (2010) Linda Müller et al. MOLECULAR BIOLOGY OF THE CELL
- Effect of MK-886 on Ca2+Level and Viability in PC3 Human Prostate Cancer Cells
- (2009) Jong-Khing Huang et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- RNA-Based Therapeutics: Ready for Delivery?
- (2009) Laura Bonetta CELL
- Minireview: Delivering the Code: Polyplex Carriers for Deoxyribonucleic Acid and Ribonucleic Acid Interference Therapies
- (2009) R. James Christie et al. ENDOCRINOLOGY
- TRPC5 Is a Ca2+-activated Channel Functionally Coupled to Ca2+-selective Ion Channels
- (2009) Stefan Alfred Gross et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
- (2009) Aimee L. Jackson et al. NATURE REVIEWS DRUG DISCOVERY
- Calmodulin modulates Akt activity in human breast cancer cell lines
- (2008) Christine M. Coticchia et al. BREAST CANCER RESEARCH AND TREATMENT
- A new non-disruptive strategy to target calcium indicator dyes to the endoplasmic reticulum
- (2008) Markus Rehberg et al. CELL CALCIUM
- Global public health: a scorecard
- (2008) Robert Beaglehole et al. LANCET
- Lung Cancer
- (2008) Roy S. Herbst et al. NEW ENGLAND JOURNAL OF MEDICINE
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