Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc −/+ ice

Silibinin Suppresses Growth of Human Colorectal Carcinoma SW480 Cells in Culture and Xenograft through Down-regulation of β-Catenin-Dependent Signaling

(2015) Manjinder Kaur et al.   NEOPLASIA

Silibinin triggers apoptotic signaling pathways and autophagic survival response in human colon adenocarcinoma cells and their derived metastatic cells

(2011) Henriette Kauntz et al.   APOPTOSIS

Effect of silibinin in human colorectal cancer cells: Targeting the activation of NF-κB signaling

(2011) Komal Raina et al.   MOLECULAR CARCINOGENESIS

Chemoprevention of Intestinal Tumorigenesis in APCmin/+ Mice by Silibinin

(2010) S. Rajamanickam et al.   CANCER RESEARCH

Establishment of human dental epithelial cell lines expressing ameloblastin and enamelin by transfection of hTERT and cdk4 cDNAs

(2010) Setsuko Hatakeyama et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Molecular mechanisms for chemoprevention of colorectal cancer by natural dietary compounds

(2010) Min-Hsiung Pan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Induction of G1 and G2/M cell cycle arrests by the dietary compound 3,3'-diindolylmethane in HT-29 human colon cancer cells

(2009) Hyun Ju Choi et al.   BMC GASTROENTEROLOGY

Quercetin Inhibit Human SW480 Colon Cancer Growth in Association with Inhibition of Cyclin D1and Survivin Expression through Wnt/β-Catenin Signaling Pathway

(2009) Bao-En Shan et al.   CANCER INVESTIGATION

Silibinin modulates biotransforming microbial enzymes and prevents 1,2-dimethylhydrazine-induced preneoplastic changes in experimental colon cancer

(2009) Nagarajan Sangeetha et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

Overexpression of Reg3α increases cell growth and the levels of cyclin D1 and CDK4 in insulinoma cells

(2009) Wei Cui et al.   GROWTH FACTORS

Silibinin suppresses growth and induces apoptotic death of human colorectal carcinoma LoVo cells in culture and tumor xenograft

(2009) M. Kaur et al.   MOLECULAR CANCER THERAPEUTICS

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

Inhibition of Azoxymethane-Induced Colonic Aberrant Crypt Foci Formation by Silibinin in Male Fisher 344 Rats

(2008) B. Velmurugan et al.   Cancer Prevention Research

C-Myc Is a Critical Mediator of the Phenotypes of Apc Loss in the Intestine

(2008) J. A. Wilkins et al.   CANCER RESEARCH

Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide

(2008) Ming-Der Shi et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chemoprevention of Colorectal Neoplasia: The Potential for Personalized Medicine

(2008) Nadir Arber et al.   GASTROENTEROLOGY