Article
Chemistry, Medicinal
Xiaofei Mo, Tianyun Zhao, Jinghui Chen, Xiang Li, Jun Liu, Cuiyi Xu, Xingrong Song
Summary: Programmed intermittent epidural bolus provides more effective pain relief and less motor block after cesarean section, without an increased risk of urinary retention and blood pressure instability.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Pharmacology & Pharmacy
Fangfang Miao, Kunpeng Feng, Xuexin Feng, Long Fan, Yu Lang, Qingfang Duan, Ruixue Hou, Di Jin, Tianlong Wang
Summary: This study investigated the optimal concentrations of ropivacaine and sufentanil for controlling postoperative pain after cesarean section. The results showed that the combination of 0.15% ropivacaine and 0.5 mu g/ml sufentanil administered epidurally led to lower pain scores, improved patient satisfaction, and shorter time to first flatus, but also increased the incidence of pruritus and numbness.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Pharmacology & Pharmacy
Liang Sun, Shuo Guan, Dou Dou, Yi Feng, Hong Zhang, Haiyan An
Summary: This study aimed to evaluate the impact of different doses of epidural morphine plus ropivacaine on maternal outcomes. The results showed that compared with 6mg morphine, epidural 3mg morphine plus 0.1% ropivacaine can provide equal efficacy and have a lower incidence of urinary retention after cesarean section.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Medicine, General & Internal
Malia S. Q. Murphy, Robin Ducharme, Steven Hawken, Daniel J. Corsi, William Petrcich, Darine El-Chaar, Lise Bisnaire, Daniel I. McIsaac, Deshayne B. Fell, Shi Wu Wen, Mark C. Walker
Summary: This study found that intrapartum epidural analgesia was associated with a small increase in the risk of ASD in offspring. However, the biological plausibility of this association remains unclear, and caution should be exercised when interpreting the findings.
Article
Medicine, General & Internal
Go Otao, Toyoaki Maruta, Isao Tsuneyoshi
Summary: The study showed that combining fentanyl 10 mcg/h after single morphine administration or using local anesthetic alone post-operatively is generally effective for patient-controlled epidural analgesia (PCEA) after cesarean section, while combining fentanyl 20 mcg/h is more suitable for conventional epidural analgesia.
Article
Obstetrics & Gynecology
Chan Shen, Lin Chen, Chengjin Yue, Jing Cheng
Summary: This study investigated the effectiveness of extending epidural analgesia for intrapartum cesarean section. The results showed that using a well-functioning epidural catheter for extending epidural analgesia may be a reliable and effective anesthetic method.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
(2022)
Article
Medicine, General & Internal
Zhang Jian, Ran Longqing, Wei Dayuan, Jia Fei, Liu Bo, Zhang Gang, Zhu Siying, Gao Yan
Summary: This study summarizes the process of converting epidural labour analgesia to anaesthesia for caesarean delivery and explores the relationship between the duration of labour analgesia and conversion failure. The results show that prolonged duration of epidural labour analgesia is an independent risk factor for conversion failure, especially when it exceeds 8 hours.
ANNALS OF MEDICINE
(2022)
Article
Statistics & Probability
Matthew Blackwell, Nicole E. Pashley
Summary: This article introduces a new methodology for analyzing factorial experiments with treatment noncompliance using the potential outcomes framework. The methodology extends the existing literature on instrumental variables and factorial experiments by defining new quantities of interest, generalizing instrumental variables assumptions, and conducting inference from both finite-population and superpopulation perspectives. It also provides an easy-to-use, open-source software for implementation.
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
(2023)
Article
Clinical Neurology
Jingwen Zhuang, Qianmin Chen, Chao Liu, Ronghua Zuo, Yuhan Zhang, Jingjing Dang, Zhiping Wang
Summary: This study aimed to investigate the association between maternal childbirth intention, labor epidural analgesia (LEA), and postpartum depression (PPD), as well as risk factors related to PPD. The results showed no significant association between childbirth intention, LEA, and PPD, while chronic pain affecting daily life, prenatal EPDS, SAS, SSRS score, family accompaniment during labor, and 1-day NRS score were significantly associated with PPD.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Medicine, General & Internal
Miha Lucovnik, Ivan Verdenik, Tatjana Stopar Pintaric
Summary: In this study, the associations between the types of labor analgesia and the outcomes of singleton breech and twin vaginal births were examined. It was found that there were no significant differences in the outcomes between epidural analgesia and remifentanil patient-controlled analgesia.
MEDICINA-LITHUANIA
(2023)
Article
Chemistry, Medicinal
Lini Wang, Yiting Wang, Yumei Ma, Xiaoxiao Mu, Zhen Zhang, Huan Wang, Ziyu Zheng, Huang Nie
Summary: Compared with sufentanil alone, the combination of sufentanil and nalbuphine for patient-controlled intravenous analgesia (PCIA) after cesarean section (CS) provided better pain relief in parturient women. The combination group had lower pain scores at rest and with movement at 24 and 48 hours after CS. Additionally, the PCIA bolus times were lower and the rates of bradycardia and respiratory depression were lower in the combination group.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Article
Surgery
Ju Tang, Zhiguo Zheng, Qijun Ran, Feng Zhao, Yao Wang, Feng Hu, Chao Yang, Xiaoyong Tan
Summary: The aim of this study was to examine whether the addition of esketamine to morphine could improve postoperative analgesia after cesarean section. The results showed that patients who received 0.25 mg/kg esketamine plus 2 mg morphine through the epidural catheters had significantly lower pain scores at rest and with movement compared to the other groups, and they also required fewer rescue analgesics. Additionally, the addition of esketamine did not increase the incidence of adverse events.
FRONTIERS IN SURGERY
(2023)
Article
Medicine, General & Internal
Mi Roung Jun, Moon Ok Lee, Haeng Seon Shim, Jeong Won Park, Jeong Yeon Kim, Sungbo Shim, Jihoon Lee
Summary: This study retrospectively reviewed the records of 632 patients undergoing cesarean section and prescribed IVPCA. The study found that setting an appropriate initial IVA regimen with a basal rate infusion significantly reduced the rate of second prescription, but increased the incidence of complications. Therefore, for postoperative pain management in cesarean section patients, it is important to properly set the initial IVA regimen.
Article
Medicine, General & Internal
Chun-Yu Chang, Yu-Kang Tu, Ming-Chang Kao, Ping-Cheng Shih, I-Min Su, Han-Yu Lin, Yung-Jiun Chien, Meng-Yu Wu, Chih-Hao Chen, Chu-Ting Chen
Summary: This study aimed to evaluate the analgesic and adverse effects of opioids administered via IVPCA or PCEA in parturients who have undergone caesarean section. The findings showed that PCEA fentanyl had better analgesic effects and lower odds of developing nausea/vomiting and sedation/drowsiness compared to IVPCA morphine. However, PCEA fentanyl may be more likely to cause pruritus.
Article
Multidisciplinary Sciences
Wisdom Klutse Azanu, Joseph Osarfo, Roderick Emil Larsen-Reindorf, Evans Kofi Agbeno, Edward Dassah, Anthony Ofori Amanfo, Anthony Kwame Dah, Gifty Ampofo
Summary: Inadequate pain control was found in post-caesarean section women within the first 12 hours, potentially impacting early mother-child interaction. Some participants did not receive analgesics as prescribed. Exploration of adjunct pain control measures is recommended, and healthcare workers should pay more attention to patients' pain relief needs.
Review
Gastroenterology & Hepatology
Joel E. Richter, Ambuj Kumar, Seth Lipka, Branko Miladinovic, Vic Velanovich
Letter
Obstetrics & Gynecology
Sarah Pont, Kathryn Austin, Ibinabo Ibiebele, Siranda Torvaldsen, Jillian Patterson, Jane Ford
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2019)
Article
Obstetrics & Gynecology
Ibinabo Ibiebele, Jennifer R. Bowen, Tanya A. Nippita, Jonathan M. Morris, Jane B. Ford
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2019)
Article
Obstetrics & Gynecology
Sarah Pont, Kathryn Austin, Ibinabo Ibiebele, Siranda Torvaldsen, Jillian Patterson, Jane Ford
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2019)
Review
Environmental Sciences
Shannon M. Melody, Jane Ford, Karen Wills, Alison Venn, Fay H. Johnston
ENVIRONMENTAL POLLUTION
(2019)
Article
Obstetrics & Gynecology
Jillian A. Patterson, Siranda Torvaldsen, Tanya A. Nippita, Jane B. Ford, Jonathan M. Morris
AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY
(2020)
Article
Public, Environmental & Occupational Health
Edward Jegasothy, Deborah A. Randall, Jane B. Ford, Tanya A. Nippita, Geoffrey G. Morgan
Summary: Exposure to high temperatures increases the risk of preterm birth, especially for women with pre-existing health conditions and who smoke during pregnancy.
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY
(2022)
Meeting Abstract
Oncology
Howard M. Sandler, Stephen J. Freedland, Neal D. Shore, Matthew Raymond Smith, Rosamerlinda S. Rosales, Sabine D. Brookman-May, David P. Dearnaley, Adam P. Dicker, Michael R. McKenzie, Alberto Bossi, Anders Widmark, Thomas Wiegel, Jason L. Martin, Branko Miladinovic, Jennifer Anne Whalen, Marika Ciprotti, Sharon McCarthy, Suneel Mundle, Bertrand F. Tombal, Felix Y. Feng
JOURNAL OF CLINICAL ONCOLOGY
(2022)
Meeting Abstract
Oncology
Rahul Raj Aggarwal, Joshi J. Alumkal, Russell Zelig Szmulewitz, Celestia S. Higano, Alan Haruo Bryce, Angela Lopez-Gitlitz, Sharon Anne McCarthy, Branko Miladinovic, Kelly McQuarrie, Shibu Thomas, Eric Jay Small
JOURNAL OF CLINICAL ONCOLOGY
(2020)
Article
Surgery
Tambi Jarmi, Nirav Patel, Sadaf Aslam, George Makdisi, Elias Doumit, Rahul Mhaskar, Branko Miladinovic, Mark Weston
ANNALS OF TRANSPLANTATION
(2018)
Review
Medicine, General & Internal
Rahul Mhaskar, Ambuj Kumar, Branko Miladinovic, Benjamin Djulbegovic
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2017)
Meeting Abstract
Obstetrics & Gynecology
Lindsay Maggio, Branko Miladinovic, Douglas Slain, Omar M. Young, Joshua D. Dahlke, Michael Stitely, Michael Sweet, Raman Venkataramanan, Steve Caritis, David P. Nicolau, Brenna L. Hughes
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2017)
Article
Obstetrics & Gynecology
Heather J. Baldwin, Jillian A. Patterson, Tanya A. Nippita, Siranda Torvaldsen, Ibinabo Ibiebele, Judy M. Simpson, Jane B. Ford
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2017)
Article
Obstetrics & Gynecology
Yu Sun Bin, Jane B. Ford, Michael C. Nicholl, Christine L. Roberts
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2017)
Article
Urology & Nephrology
Gabriela E. Halder, Lauren Scott, Allison Wyman, Nelsi Mora, Branko Miladinovic, Renee Bassaly, Lennox Hoyte
INVESTIGATIVE AND CLINICAL UROLOGY
(2017)