Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α

14-3-3 Proteins Interact with a Hybrid Prenyl-Phosphorylation Motif to Inhibit G Proteins

(2013) Philippe Riou et al.   CELL

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response

(2011) Maruf M U Ali et al.   EMBO JOURNAL

Potent and Selective Inhibitors of the Inositol-requiring Enzyme 1 Endoribonuclease

(2011) Kori Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Attenuation of yeast UPR is essential for survival and is mediated byIRE1kinase

(2011) Aditi Chawla et al.   JOURNAL OF CELL BIOLOGY

Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response

(2011) B. M. Gardner et al.   SCIENCE

XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

(2010) T. Bagratuni et al.   BLOOD

The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27

(2010) Ziguo Zhang et al.   EMBO JOURNAL

Inositol-requiring enzyme 1  is a key regulator of angiogenesis and invasion in malignant glioma

(2010) G. Auf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering

(2010) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of mammalian IRE1α upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins

(2009) Daisuke Oikawa et al.   EXPERIMENTAL CELL RESEARCH

Structure of the Dual Enzyme Ire1 Reveals the Basis for Catalysis and Regulation in Nonconventional RNA Splicing

(2008) Kenneth P.K. Lee et al.   CELL

The unfolded protein response signals through high-order assembly of Ire1

(2008) Alexei V. Korennykh et al.   NATURE