Acid-sensing ion channels (ASICs): therapeutic targets for neurological diseases and their regulation

Neurosensory mechanotransduction through acid-sensing ion channels

(2013) Chih-Cheng Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Acid-Sensing Ion Channel-1a Is Not Required for Normal Hippocampal LTP and Spatial Memory

(2013) P.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Acid-sensing ion channels: trafficking and synaptic function

(2013) Xiang-ming Zha   Molecular Brain

AMP-activated protein kinase: implications on ischemic diseases

(2012) Yong-Joo Ahn et al.   BMB Reports

Impact of Recovery from Desensitization on Acid-sensing Ion Channel-1a (ASIC1a) Current and Response to High Frequency Stimulation

(2012) Tianbo Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subtype-specific Modulation of Acid-sensing Ion Channel (ASIC) Function by 2-Guanidine-4-methylquinazoline

(2012) Omar Alijevic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PI3-kinase/Akt Pathway-Regulated Membrane Insertion of Acid-Sensing Ion Channel 1a Underlies BDNF-Induced Pain Hypersensitivity

(2012) B. Duan et al.   JOURNAL OF NEUROSCIENCE

Black mamba venom peptides target acid-sensing ion channels to abolish pain

(2012) Sylvie Diochot et al.   NATURE

Potentiation of acid-sensing ion channel activity by the activation of 5-HT2 receptors in rat dorsal root ganglion neurons

(2012) Fang Qiu et al.   NEUROPHARMACOLOGY

Cannabinoids Inhibit Acid-Sensing Ion Channel Currents in Rat Dorsal Root Ganglion Neurons

(2012) Yu-Qiang Liu et al.   PLoS One

Detecting activity-evoked pH changes in human brain

(2012) V. A. Magnotta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nonproton Ligand Sensing Domain Is Required for Paradoxical Stimulation of Acid-sensing Ion Channel 3 (ASIC3) Channels by Amiloride

(2011) Wei-Guang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Serotonin Receptor 5-HT2B Mediates Serotonin-Induced Mechanical Hyperalgesia

(2011) S.-Y. Lin et al.   JOURNAL OF NEUROSCIENCE

Heteromeric Acid-Sensing Ion Channels (ASICs) Composed of ASIC2b and ASIC1a Display Novel Channel Properties and Contribute to Acidosis-Induced Neuronal Death

(2011) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

Extracellular Spermine Exacerbates Ischemic Neuronal Injury through Sensitization of ASIC1a Channels to Extracellular Acidosis

(2011) B. Duan et al.   JOURNAL OF NEUROSCIENCE

A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain

(2011) Christopher J. Bohlen et al.   NATURE

An antinociceptive role for substance P in acid-induced chronic muscle pain

(2011) C.-C. J. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Calcium Permeable Human Acid-sensing Ion Channel 1 Transcript Variant

(2010) Erin N. Hoagland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Nonproton Ligand Sensor in the Acid-Sensing Ion Channel

(2010) Ye Yu et al.   NEURON

Modulation of High-Voltage Activated Ca2+ Channels by Membrane Phosphatidylinositol 4,5-Bisphosphate

(2010) Byung-Chang Suh et al.   NEURON

Current perspectives on acid-sensing ion channels: new advances and therapeutic implications

(2010) Jacques Noël et al.   Expert Review of Clinical Pharmacology

Cellular and Molecular Mechanisms of Pain

(2009) Allan I. Basbaum et al.   CELL

Native and recombinant ASIC1a receptors conduct negligible Ca2+ entry

(2009) Damien S.K. Samways et al.   CELL CALCIUM

Identification of Protein Domains That Control Proton and Calcium Sensitivity of ASIC1a

(2009) Thomas Sherwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynorphin Opioid Peptides Enhance Acid-Sensing Ion Channel 1a Activity and Acidosis-Induced Neuronal Death

(2009) T. W. Sherwood et al.   JOURNAL OF NEUROSCIENCE

ASIC2 Subunits Target Acid-Sensing Ion Channels to the Synapse via an Association with PSD-95

(2009) X.-m. Zha et al.   JOURNAL OF NEUROSCIENCE

ASIC1 and ASIC3 Play Different Roles in the Development of Hyperalgesia After Inflammatory Muscle Injury

(2009) Roxanne Y. Walder et al.   JOURNAL OF PAIN

The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation

(2009) Yongjun Lu et al.   NEURON

Muscarinic M1 modulation of acid-sensing ion channels

(2009) Natalia A. Dorofeeva et al.   NEUROREPORT

PIP2 Is a Necessary Cofactor for Ion Channel Function: How and Why?

(2008) Byung-Chang Suh et al.   Annual Review of Biophysics

Arachidonic acid and ion channels: an update

(2008) H Meves   BRITISH JOURNAL OF PHARMACOLOGY

ASIC3, a sensor of acidic and primary inflammatory pain

(2008) Emmanuel Deval et al.   EMBO JOURNAL

Acid Sensing Ion Channels in Dorsal Spinal Cord Neurons

(2008) A. Baron et al.   JOURNAL OF NEUROSCIENCE

Seizure termination by acidosis depends on ASIC1a

(2008) Adam E Ziemann et al.   NATURE NEUROSCIENCE

Role of ASIC3 in the primary and secondary hyperalgesia produced by joint inflammation in mice

(2008) M. Ikeuchi et al.   PAIN

Acid-sensing ion channels (ASICs) as pharmacological targets for neurodegenerative diseases

(2007) Z XIONG et al.   CURRENT OPINION IN PHARMACOLOGY