期刊
BLOOD PURIFICATION
卷 34, 期 1, 页码 58-66出版社
KARGER
DOI: 10.1159/000338184
关键词
Autonomic nerve function; Heart rate variability; Peritoneal dialysis; Residual renal function
资金
- National Natural Science Foundation of China [30900681]
- Beijing Municipal Science and Technology Commission [D09050704310905]
- Fund of Peking University Third Hospital [76496-02]
Background: The relationship between heart rate variability (HRV) and residual renal function (RRF) has not been elucidated previously. Methods: In this cross-sectional study, HRV was evaluated in 71 peritoneal dialysis patients. Patients were divided into RRF decline group, RRF stable group and anuric group. Results: RRF was negatively correlated with SDNN (r = -0.284, p = 0.017), TP (r = -0.247, p = 0.039), and HF (r = -0.238, p = 0.047). Significant sympathetic nerve activation was found in the RRF decline group (significantly lower SDNN, SDSD, RMSSD, pNN50, LF, HF, TP and higher LF/HF ratio) as compared to the RRF stable and anuric groups. Besides, significantly parasympathetic activation was found in the anuric group (the lowest LF/HF ratio as compared to the other groups (both p < 0.05). Multivariate stepwise regression analysis showed that the status of RRF was an independent factor associated with HRV parameters. Conclusion: This study showed autonomic nervous function in peritoneal dialysis patients was associated with a different status of RRF. Copyright (c) 2012 S. Karger AG, Basel
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