Article
Cardiac & Cardiovascular Systems
Weiqi Feng, Qiuji Wang, Chenxi Li, Jinlin Wu, Juntao Kuang, Jue Yang, Ruixin Fan
Summary: This study explores the relationship between admission D-dimer levels and in-hospital major adverse events (MAE) in patients with acute type A aortic dissection (ATAAD). The results indicate that increasing D-dimer levels are independently associated with MAE during hospitalization, suggesting that D-dimer can be used as a useful prognostic biomarker before surgery.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Yan Huo, Hui Zhang, Bo Li, Kun Zhang, Bin Li, Shao-Han Guo, Zhen-Jie Hu, Gui-Jun Zhu
Summary: The study explored the risk factors of postoperative mortality in patients with acute Stanford type A aortic dissection. Results indicated that a high BMI, high SOFA score, prolonged duration of cardiopulmonary bypass assistance, postoperative low cardiac output, and postoperative DIC were independent risk factors for death. Other factors such as intraoperative blood transfusion, postoperative hepatic failure, and AKI were associated with increased risk of death but not independent risk factors.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2021)
Article
Surgery
Xichun Qin, Yaxuan Gao, Yi Jiang, Feng Zhu, Wei Xie, Xinlong Tang, Yunxing Xue, Dongjin Wang, Hailong Cao
Summary: Identifying risk prognosis factors is crucial for the risk stratification of patients with Acute Stanford-A aortic dissection (AAAD). This study investigated the peripheral blood eosinophil (EOS) counts in AAAD patients and their potential biological implications. The findings suggest that the EOS counts may be involved in thrombosis and could serve as an effective indicator for the diagnosis, evaluation, and prognosis monitoring of AAAD patients.
FRONTIERS IN SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
Yansong Xu, Silei Liang, Zheng Liang, Cuiqing Huang, Yihuan Luo, Guanbiao Liang, Wei Wang
Summary: Inflammatory factors are well-established indicators for vascular disease. The D-dimer to lymphocyte count ratio (DLR) can be used to assess in-hospital mortality in patients with acute aortic dissection (AD). Higher DLR levels are associated with higher in-hospital mortality rates. DLR, heart rate (HR), and prothrombin time (PT) are independent predictors of in-hospital mortality.
BMC CARDIOVASCULAR DISORDERS
(2023)
Article
Multidisciplinary Sciences
Peng-fei Huang, Yun-jing Zhang, Xian-zhe Lou, Dong Ma, Yun-yan Wu, Yong-bo Zhao
Summary: Acute Stanford type A aortic dissection (ATAAD) is a life-threatening condition that requires urgent treatment. This study evaluated the prognostic value of CO2 combining power (CO2CP) combined with serum sodium levels in ATAAD patients. The combination of CO2CP and serum sodium showed a higher predictive value for death and adverse events in ATAAD patients compared to each single indicator. Patients with low CO2CP and high serum sodium had the worst prognosis. The combination of CO2CP and serum sodium can enhance the predictive value of prognosis in ATAAD patients.
SCIENTIFIC REPORTS
(2023)
Article
Cardiac & Cardiovascular Systems
Lin Yang, Yasong Wang, Xiaofeng He, Xuanze Liu, Honggang Sui, Xiaozeng Wang, Mengmeng Wang
Summary: This study aimed to identify risk factors and develop a prognostic dynamic nomogram for in-hospital mortality in patients with TBAD. Several variables were found to be associated with in-hospital mortality. The prediction model demonstrated good discrimination and clinical utility.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Junquan Chen, Yunpeng Bai, Hong Liu, Mingzhen Qin, Zhigang Guo
Summary: The study aimed to create a prediction model for in-hospital death in Chinese patients with acute type A aortic dissection (ATAAD). A retrospective derivation cohort of 340 patients from Tianjin and a retrospective validation cohort of 153 patients from Nanjing were used. Variable selection was done using least absolute shrinkage and selection operator analysis, and risk scoring was done using logistic regression coefficients. A risk classifier was established based on independent baseline data using a multivariable logistic model. The prediction performance was evaluated using the receiver operating characteristic curve (ROC). Individualized clinical decision-making was conducted using decision curve analysis (DCA). The risk prediction model showed good performance in predicting in-hospital death in ATAAD patients.
FRONTIERS IN PUBLIC HEALTH
(2023)
Review
Medicine, General & Internal
Hai-Yuan Liu, Shuai-Peng Zhang, Cheng-Xin Zhang, Qing-Yun Gao, Yu-Yong Liu, Sheng-Lin Ge
Summary: Surgical treatment is the preferred and reliable option for Stanford type A aortic dissection, but postoperative complications are relatively higher due to the complexity of the disease and its procedure. Hypoxemia is considered to play an important role in the clinical prognosis, and effective intervention is significant for the improved prognosis of patients with Stanford type A aortic dissection.
WORLD JOURNAL OF CLINICAL CASES
(2023)
Article
Multidisciplinary Sciences
Ming Li, Suochun Xu, Yang Yan, Haichen Wang, Jianjie Zheng, Yongxin Li, Yongjian Zhang, Junjun Hao, Chao Deng, Xinglong Zheng, Miaomiao Liu, Yang Gao, Xue Wang, Li Xue
Summary: This study analyzed the role of blood biomarkers in predicting postoperative in-hospital mortality of patients with type A acute aortic dissection, finding that preoperative D-dimer and white blood cell count were independent risk factors. Combining fibrinogen and platelet levels improved the accuracy of prediction.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Chen Yang, Peng Hou, Dongxu Wang, Zhenguo Wang, Weixun Duan, Jincheng Liu, Shiqiang Yu, Feng Fu, Zhenxiao Jin
Summary: The correlation between serum myoglobin and acute kidney injury in patients who underwent total aortic arch replacement with frozen elephant trunk implantation was investigated. It was found that elevated serum myoglobin levels were associated with increased risk of severe acute kidney injury. Serum myoglobin could improve the risk classification of postoperative acute kidney injury.
FRONTIERS IN MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Zhiwei Tang, Hong Liu, Yongfeng Shao
Summary: This study evaluated the efficacy of C-reactive protein (CRP) and D-dimer, as well as their combination, as prognostic indicators for patients with acute type A aortic dissection (ATAAD). The results showed that admission D-dimer, peak D-dimer, and admission CRP levels were all independently associated with in-hospital adverse outcomes. The combination of these three markers improved the predictive efficacy.
JOURNAL OF CARDIOTHORACIC SURGERY
(2022)
Article
Medical Laboratory Technology
Suwei Chen, Chenhan Zhang, Yongliang Zhong, Bing Tang, Qiang Xie, Rutao Guo, Zhiyu Qiao, Chengnan Li, Yipeng Ge, Junming Zhu
Summary: The study found a correlation between preoperative serum myoglobin concentrations and AKI after TAAD surgery, and high concentrations of serum myoglobin increased the risk of developing any-stage and severe AKI. This finding is significant for the prevention and treatment of AKI after TAAD surgery.
CLINICA CHIMICA ACTA
(2023)
Article
Endocrinology & Metabolism
Junbo Chuai, Dan Wu, Zipeng Li, Wei Chen, Chang Liu, Dawei Li, Chunfeng Zhang, Yang Zhou, Hai Tian
Summary: This study identified autophagy-related biomarkers and therapeutic targets for the diagnosis and treatment of patients susceptible to acute Stanford type A aortic dissection (ATAAD) through comprehensive analysis of GEO data.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2023)
Article
Cardiac & Cardiovascular Systems
Yosuke Inoue, Hitoshi Matsuda, Jiro Matsuo, Takayuki Shijo, Atsushi Omura, Yoshimasa Seike, Kyokun Uehara, Hiroaki Sasaki, Junjiro Kobayashi
Summary: Resection of a primary entry tear is essential for treating Stanford type A acute aortic dissection. The study found that entry exclusion through the use of new technologies like the frozen elephant trunk technique and TEVAR can help reduce dissection-related reoperations in patients with DeBakey type III retrograde-AAAD.
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Qiang Xie, Chengnan Li, Yongliang Zhong, Congcong Luo, Rutao Guo, Yongmin Liu, Jun Zheng, Yipeng Ge, Lizhong Sun, Junming Zhu
Summary: This study evaluated the impact of transfusing different blood products on postoperative mechanical ventilation time in patients with ATAAD. The study found that transfusion of pRBCs and PC, as well as age, were independent risk factors for prolonged mechanical ventilation after surgery.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)