The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via  2 integrins (CD11/CD18)

Hematopoietic progenitor kinase 1 (HPK1) is required for LFA-1-mediated neutrophil recruitment during the acute inflammatory response

(2013) S. M. Jakob et al.   BLOOD

Intraluminal crawling versus interstitial neutrophil migration during inflammation

(2013) Robert Pick et al.   MOLECULAR IMMUNOLOGY

Midkine acts as proangiogenic cytokine in hypoxia-induced angiogenesis

(2012) Ludwig T. Weckbach et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation

(2012) C. T. Lefort et al.   BLOOD

The Mammalian Actin-Binding Protein 1 Is Critical for Spreading and Intraluminal Crawling of Neutrophils under Flow Conditions

(2012) I. Hepper et al.   JOURNAL OF IMMUNOLOGY

The integrin LFA-1 signals through ZAP-70 to regulate expression of high-affinity LFA-1 on T lymphocytes

(2011) R. Evans et al.   BLOOD

Reconstruction of integrin activation

(2011) F. Ye et al.   BLOOD

Notch Signaling Activated by Replication Stress-Induced Expression of Midkine Drives Epithelial-Mesenchymal Transition and Chemoresistance in Pancreatic Cancer

(2011) C. Gungor et al.   CANCER RESEARCH

Molecular Basis for the Interaction of Low Density Lipoprotein Receptor-related Protein 1 (LRP1) with Integrin αMβ2

(2011) Sripriya Ranganathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Cytokine Midkine and Its Receptor RPTP  Regulate B Cell Survival in a Pathway Induced by CD74

(2011) S. Cohen et al.   JOURNAL OF IMMUNOLOGY

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

(2010) D. Frommhold et al.   BLOOD

A chemotactic gradient sequestered on endothelial heparan sulfate induces directional intraluminal crawling of neutrophils

(2010) S. Massena et al.   BLOOD

Immobilized Chemokine Fields and Soluble Chemokine Gradients Cooperatively Shape Migration Patterns of Dendritic Cells

(2010) Kathrin Schumann et al.   IMMUNITY

Trapped versus Soluble Chemokines: Functions in Leukocyte Adhesion and Motility

(2010) Ronen Alon   IMMUNITY

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

A fundamental role of mAbp1 in neutrophils: impact on  2 integrin-mediated phagocytosis and adhesion in vivo

(2009) J. Schymeinsky et al.   BLOOD

Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation

(2008) David Frommhold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of midkine alleviates experimental autoimmune encephalomyelitis through the expansion of regulatory T cell population

(2008) J. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA