Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells

Epigenetic Silencing of the Proapoptotic Gene BIM in Anaplastic Large Cell Lymphoma through an MeCP2/SIN3a Deacetylating Complex

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Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigating molecular mechanisms of drug resistance

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Cell and Molecular Determinants of In Vivo Efficacy of the BH3 Mimetic ABT-263 against Pediatric Acute Lymphoblastic Leukemia Xenografts

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CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

(2013) D. Beck et al.   BLOOD

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

(2013) E. Diffner et al.   BLOOD

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

(2013) Lisa C Watson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BloodChIP: a database of comparative genome-wide transcription factor binding profiles in human blood cells

(2013) Diego Chacon et al.   NUCLEIC ACIDS RESEARCH

A 50-Year Journey to Cure Childhood Acute Lymphoblastic Leukemia

(2013) Ching-Hon Pui et al.   SEMINARS IN HEMATOLOGY

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Erg and AP-1 as determinants of glucocorticoid response in acute lymphoblastic leukemia

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FOXO3 Is a Glucocorticoid Receptor Target and Regulates LKB1 and Its Own Expression Based on Cellular AMP Levels via a Positive Autoregulatory Loop

(2012) Nicolas Lützner et al.   PLoS One

Structures of KIX domain of CBP in complex with two FOXO3a transactivation domains reveal promiscuity and plasticity in coactivator recruitment

(2012) F. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glucocorticoid-mediated BIM induction and apoptosis are regulated by Runx2 and c-Jun in leukemia cells

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Regulation of mitochondrial metabolism: yet another facet in the biology of the oncoprotein Bcl-2

(2011) Shefali Krishna et al.   BIOCHEMICAL JOURNAL

Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia

(2011) Vivek A Bhadri et al.   BMC GENOMICS

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition

(2010) P. S. Bachmann et al.   BLOOD

Glucocorticoid use in acute lymphoblastic leukaemia

(2010) Hiroto Inaba et al.   LANCET ONCOLOGY

Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions

(2010) Ville Paakinaho et al.   MOLECULAR ENDOCRINOLOGY

Glucocorticoid Receptor Activation of theCiz1-Lcn2Locus by Long Range Interactions

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Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

(2008) J. E. Pimanda et al.   BLOOD

Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95

(2008) A. Moricke et al.   BLOOD

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia

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Chromatin Remodeling Complexes Interact Dynamically with a Glucocorticoid Receptor–regulated Promoter

(2008) Thomas A. Johnson et al.   MOLECULAR BIOLOGY OF THE CELL

Interaction of the Glucocorticoid Receptor with the Chromatin Landscape

(2008) Sam John et al.   MOLECULAR CELL