Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation

Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome

(2013) Daniel Kotlarz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Membrane-bound interleukin-21 and CD137 ligand induce functional human natural killer cells from peripheral blood mononuclear cells through STAT-3 activation

(2012) X. Wang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Targeting the Interleukin-6/Jak/Stat Pathway in Human Malignancies

(2012) Pasquale Sansone et al.   JOURNAL OF CLINICAL ONCOLOGY

Natural Killer Cell Functional Defects in Pediatric Patients With Severe and Recurrent Herpesvirus Infections

(2012) Bradley W. Ornstein et al.   JOURNAL OF INFECTIOUS DISEASES

Membrane-Bound IL-21 Promotes Sustained Ex Vivo Proliferation of Human Natural Killer Cells

(2012) Cecele J. Denman et al.   PLoS One

Signal Transducer and Activator of Transcription 3 (STAT3) and Suppressor of Cytokine Signaling (SOCS3) Balance Controls Cytotoxicity and IL-10 Expression in Decidual-Like Natural Killer Cell Line NK-92

(2011) Anne Braunschweig et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the  c cytokines and TGF- 1

(2011) Y. P. Park et al.   BLOOD

A Critical Role for STAT3 Transcription Factor Signaling in the Development and Maintenance of Human T Cell Memory

(2011) Andrea M. Siegel et al.   IMMUNITY

STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction

(2010) H. Nguyen-Jackson et al.   BLOOD

Natural-killer cell amplification for adoptive leukemia relapse immunotherapy: Comparison of three cytokines, IL-2, IL-15, or IL-7 and impact on NKG2D, KIR2DL1, and KIR2DL2 expression

(2010) Véronique Decot et al.   EXPERIMENTAL HEMATOLOGY

Diffuse Large B Cell Lymphoma in Hyper-IgE Syndrome Due To STAT3 Mutation

(2010) Attila Kumánovics et al.   JOURNAL OF CLINICAL IMMUNOLOGY

In-vitro IL-2 or IFN-α-induced NKG2D and CD161 NK cell receptor expression indicates novel aspects of NK cell activation in metastatic melanoma patients

(2010) Gordana Konjević et al.   MELANOMA RESEARCH

Interleukin-10: new perspectives on an old cytokine

(2009) David M. Mosser et al.   IMMUNOLOGICAL REVIEWS

A Programmed Switch from IL-15- to IL-2-Dependent Activation in Human NK Cells

(2009) Anne-Hélène Pillet et al.   JOURNAL OF IMMUNOLOGY

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

NK cells and cancer immunosurveillance

(2008) I Waldhauer et al.   ONCOGENE

The function of Stat3 in tumor cells and their microenvironment

(2008) Bernd Groner et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The NKG2D receptor: sensing stressed cells

(2008) Carlos López-Larrea et al.   TRENDS IN MOLECULAR MEDICINE

Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

(2007) Kresten Skak et al.   IMMUNOLOGY