Loss of SPARC protects hematopoietic stem cells from chemotherapy toxicity by accelerating their return to quiescence

SPARC promotes leukemic cell growth and predicts acute myeloid leukemia outcome

(2014) Houda Alachkar et al.   JOURNAL OF CLINICAL INVESTIGATION

Kit Regulates Maintenance of Quiescent Hematopoietic Stem Cells

(2014) L. A. Thoren et al.   JOURNAL OF IMMUNOLOGY

Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization

(2013) Melania Tesio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

(2013) Fabienne Brenet et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stromal SPARC contributes to the detrimental fibrotic changes associated with myeloproliferation whereas its deficiency favors myeloid cell expansion

(2012) C. Tripodo et al.   BLOOD

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration

(2012) Dongsu Park et al.   Cell Stem Cell

SPARC promotes the development of erythroid progenitors

(2012) Zhen Luo et al.   EXPERIMENTAL HEMATOLOGY

SPARC is dispensable for murine hematopoiesis, despite its suspected pathophysiological role in 5q-myelodysplastic syndrome

(2012) K Siva et al.   LEUKEMIA

Endothelial and perivascular cells maintain haematopoietic stem cells

(2012) Lei Ding et al.   NATURE

Nonmyelinating Schwann Cells Maintain Hematopoietic Stem Cell Hibernation in the Bone Marrow Niche

(2011) Satoshi Yamazaki et al.   CELL

The regulatory function of SPARC in vascular biology

(2011) Lee B. Rivera et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity

(2011) Lee B. Rivera et al.   JOURNAL OF CELL BIOLOGY

The bone marrow stem cell niche grows up: mesenchymal stem cells and macrophages move in

(2011) Armin Ehninger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD81 Is Essential for the Re-entry of Hematopoietic Stem Cells to Quiescence following Stress-Induced Proliferation Via Deactivation of the Akt Pathway

(2011) Kuanyin K. Lin et al.   PLOS BIOLOGY

The Stromal Cell Marker SPARC Predicts for Survival in Patients With Diffuse Large B-Cell Lymphoma Treated With Rituximab

(2010) Paul N. Meyer et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Persistent Activation of the Fyn/ERK Kinase Signaling Axis Mediates Imatinib Resistance in Chronic Myelogenous Leukemia Cells through Upregulation of Intracellular SPARC

(2010) N. Fenouille et al.   CANCER RESEARCH

Quiescent haematopoietic stem cells are activated by IFN-γ in response to chronic infection

(2010) Megan T. Baldridge et al.   NATURE

IFNα activates dormant haematopoietic stem cells in vivo

(2009) Marieke A. G. Essers et al.   NATURE

Anti-SPARC oligopeptide inhibits laser-induced CNV in mice

(2009) Hironori Uehara et al.   VISION RESEARCH

TGF-  as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation

(2008) S. Yamazaki et al.   BLOOD

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

SPARC in cancer biology: Its role in cancer progression and potential for therapy

(2008) Isabella T. Tai et al.   DRUG RESISTANCE UPDATES

Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells

(2008) Adlen Foudi et al.   NATURE BIOTECHNOLOGY