Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P)

Does size matter in platelet production?

(2012) J. N. Thon et al.   BLOOD

Dasatinib: From Treatment of Imatinib-Resistant or -Intolerant Patients With Chronic Myeloid Leukemia to Treatment of Patients With Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia

(2012) Brian L. Abbott   CLINICAL THERAPEUTICS

A novel role of sphingosine 1-phosphate receptor S1pr1 in mouse thrombopoiesis

(2012) Lin Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Microtubule and cortical forces determine platelet size during vascular platelet production

(2012) Jonathan N Thon et al.   Nature Communications

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

(2011) A. Mazharian et al.   BLOOD

Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: 2-year follow-up from a randomized phase 3 trial (DASISION)

(2011) H. M. Kantarjian et al.   BLOOD

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

(2011) Emma C. Josefsson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Critical role of Src-Syk-PLC 2 signaling in megakaryocyte migration and thrombopoiesis

(2010) A. Mazharian et al.   BLOOD

A Role for S1P and S1P1 in Immature-B Cell Egress from Mouse Bone Marrow

(2010) João Pedro Pereira et al.   PLoS One

Platelet Formation

(2010) Jonathan N. Thon et al.   SEMINARS IN HEMATOLOGY

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE

T-bet–dependent S1P5expression in NK cells promotes egress from lymph nodes and bone marrow

(2009) Craig N. Jenne et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors

(2008) M. Ouyang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA