Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

(2010) V. Conter et al.   BLOOD

Positioning of bone marrow hematopoietic and stromal cells relative to blood flow in vivo: serially reconstituting hematopoietic stem cells reside in distinct nonperfused niches

(2010) I. G. Winkler et al.   BLOOD

The endosteal ‘osteoblastic’ niche and its role in hematopoietic stem cell homing and mobilization

(2010) J-P Lévesque et al.   LEUKEMIA

Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with  9 1 and  4 1 integrins

(2009) J. Grassinger et al.   BLOOD

Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML

(2009) J. A. Powell et al.   BLOOD

Communications between bone cells and hematopoietic stem cells

(2008) R.L. Porter et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study

(2008) M. J. Borowitz et al.   BLOOD

Marrow osteopontin level as a prognostic factor in acute myeloid leukaemia

(2008) Cheng-Yeh Lee et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

In vivo osteopontin-induced macrophage accumulation is dependent on CD44 expression

(2008) Maria Cecilia G. Marcondes et al.   CELLULAR IMMUNOLOGY

RNA Aptamer Blockade of Osteopontin Inhibits Growth and Metastasis of MDA-MB231 Breast Cancer Cells

(2008) Zhiyong Mi et al.   MOLECULAR THERAPY

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE