Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells

(2011) S. Solito et al.   BLOOD

Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia

(2011) B. J. Frisch et al.   BLOOD

A modified EBMT risk score predicts the outcome of patients with acute myeloid leukemia receiving allogeneic stem cell transplants

(2011) Philipp G. Hemmati et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Molecular Genetics of Adult Acute Myeloid Leukemia: Prognostic and Therapeutic Implications

(2011) Guido Marcucci et al.   JOURNAL OF CLINICAL ONCOLOGY

Bone marrow CD169+macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

(2011) Andrew Chow et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dendritic Cell-Specific ICAM-3-Grabbing Nonintegrin Expression on M2-Polarized and Tumor-Associated Macrophages Is Macrophage-CSF Dependent and Enhanced by Tumor-Derived IL-6 and IL-10

(2011) A. Dominguez-Soto et al.   JOURNAL OF IMMUNOLOGY

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

(2011) Claire S. Whyte et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth

(2011) T J Standiford et al.   ONCOGENE

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

(2010) Christian Steidl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Androgen-Regulated Expression of Arginase 1, Arginase 2 and Interleukin-8 in Human Prostate Cancer

(2010) Philippe O. Gannon et al.   PLoS One

Arginase I–Producing Myeloid-Derived Suppressor Cells in Renal Cell Carcinoma Are a Subpopulation of Activated Granulocytes

(2009) Paulo C. Rodriguez et al.   CANCER RESEARCH

Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine

(2009) M. K. Srivastava et al.   CANCER RESEARCH

Myeloid-derived suppressor cell activation by combined LPS and IFN-γ treatment impairs DC development

(2009) Verena Greifenberg et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CCL2 and Interleukin-6 Promote Survival of Human CD11b+Peripheral Blood Mononuclear Cells and Induce M2-type Macrophage Polarization

(2009) Hernan Roca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uric acid decreases NO production and increases arginase activity in cultured pulmonary artery endothelial cells

(2008) Sergey Zharikov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY