T-cell receptor gene transfer exclusively to human CD8+ cells enhances tumor cell killing

CD8+ T Cells: Foot Soldiers of the Immune System

(2011) Nu Zhang et al.   IMMUNITY

A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis

(2011) Navin Varadarajan et al.   JOURNAL OF CLINICAL INVESTIGATION

Opposite Effects of Endogenous Peptide-MHC Class I on T Cell Activity in the Presence and Absence of CD8

(2011) J. D. Stone et al.   JOURNAL OF IMMUNOLOGY

Anti-CD8 Antibodies Can Trigger CD8+ T Cell Effector Function in the Absence of TCR Engagement and Improve Peptide-MHCI Tetramer Staining

(2011) M. Clement et al.   JOURNAL OF IMMUNOLOGY

DARPins: An Efficient Targeting Domain for Lentiviral Vectors

(2011) Robert C Münch et al.   MOLECULAR THERAPY

Ex vivo gene transfer and correction for cell-based therapies

(2011) Luigi Naldini   NATURE REVIEWS GENETICS

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resting lymphocyte transduction with measles virus glycoprotein pseudotyped lentiviral vectors relies on CD46 and SLAM

(2011) Qi Zhou et al.   VIROLOGY

CD4+ T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8+ T Lymphocytes

(2010) R. Bos et al.   CANCER RESEARCH

Enhanced T cell receptor gene therapy for cancer

(2010) Elisa Kieback et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer

(2010) M Perro et al.   GENE THERAPY

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors

(2010) Brigitte Anliker et al.   NATURE METHODS

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional avidity

(2009) S. Wilde et al.   BLOOD

Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity

(2009) J. R. Almeida et al.   BLOOD

Immunity to Murine Prostatic Tumors: Continuous Provision of T-Cell Help Prevents CD8 T-Cell Tolerance and Activates Tumor-Infiltrating Dendritic Cells

(2009) K. A. Shafer-Weaver et al.   CANCER RESEARCH

Pseudotyping lentiviral vectors with the wild-type measles virus glycoproteins improves titer and selectivity

(2009) S Funke et al.   GENE THERAPY

Lentiviral Vector Design for Optimal T Cell Receptor Gene Expression in the Transduction of Peripheral Blood Lymphocytes and Tumor-Infiltrating Lymphocytes

(2009) Stephanie Jones et al.   HUMAN GENE THERAPY

A Single TCR -Chain with Dominant Peptide Recognition in the Allorestricted HER2/neu-Specific T Cell Repertoire

(2009) X. Liang et al.   JOURNAL OF IMMUNOLOGY

Cell Type-Specific Targeting with Surface-Engineered Lentiviral Vectors Co-displaying OKT3 Antibody and Fusogenic Molecule

(2009) Haiguang Yang et al.   PHARMACEUTICAL RESEARCH

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

(2008) B. G. Till et al.   BLOOD

Stable transduction of quiescent T cells without induction of cycle progression by a novel lentiviral vector pseudotyped with measles virus glycoproteins

(2008) C. Frecha et al.   BLOOD

Targeted Cell Entry of Lentiviral Vectors

(2008) Sabrina Funke et al.   MOLECULAR THERAPY

Interferon-  and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells

(2008) S. H. Apte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA