Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood

(2011) H. E. Broxmeyer et al.   BLOOD

Superoxide flashes, reactive oxygen species, and the mitochondrial permeability transition pore: potential implications for hematopoietic stem cell function

(2011) Charlie Mantel et al.   CURRENT OPINION IN HEMATOLOGY

Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein

(2011) Michel Bernier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial-targeted Signal Transducer and Activator of Transcription 3 (STAT3) Protects against Ischemia-induced Changes in the Electron Transport Chain and the Generation of Reactive Oxygen Species

(2011) Karol Szczepanek et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Long-term follow-up of patients with portal vein thrombosis and myeloproliferative neoplasms

(2011) J. HOEKSTRA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Low Level of c-Kit Expression Marks Deeply Quiescent Murine Hematopoietic Stem Cells

(2011) Yoshikazu Matsuoka et al.   STEM CELLS

Inhibition of permeability transition pore opening by mitochondrial STAT3 and its role in myocardial ischemia/reperfusion

(2010) Kerstin Boengler et al.   BASIC RESEARCH IN CARDIOLOGY

STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells

(2010) I. Hazan-Halevy et al.   BLOOD

Could STAT3 provide a link between respiration and cell cycle progression?

(2010) Peter E. Shaw   CELL CYCLE

Upregulation of nascent mitochondrial biogenesis in mouse hematopoietic stem cells parallels upregulation of CD34 and loss of pluripotency: A potential strategy for reducing oxidative risk in stem cells

(2010) Charlie Mantel et al.   CELL CYCLE

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Stoichiometry of STAT3 and Mitochondrial Proteins

(2010) Darci Phillips et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolism and the leukemic stem cell: Figure 1.

(2010) Omar Abdel-Wahab et al.   JOURNAL OF EXPERIMENTAL MEDICINE

JAK2V617F and beyond: role of genetics and aberrant signaling in the pathogenesis of myeloproliferative neoplasms

(2010) Stephen T Oh et al.   Expert Review of Hematology

Quantitative Microplate-Based Respirometry with Correction for Oxygen Diffusion

(2009) Akos A. Gerencser et al.   ANALYTICAL CHEMISTRY

CELL BIOLOGY: Moonlighting in Mitochondria

(2009) M. G. Myers Jr.   SCIENCE

Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

(2009) D. J. Gough et al.   SCIENCE

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE

STAT3 Revs Up the Powerhouse

(2009) N. C. Reich   Science Signaling

SIRT1 Regulates Apoptosis and Nanog Expression in Mouse Embryonic Stem Cells by Controlling p53 Subcellular Localization

(2008) Myung-Kwan Han et al.   Cell Stem Cell

A method for measuring mitochondrial mass and activity

(2008) Maria Agnello et al.   CYTOTECHNOLOGY