标题
SRC is a signaling mediator in FLT3-ITD- but not in FLT3-TKD-positive AML
作者
关键词
-
出版物
BLOOD
Volume 119, Issue 17, Pages 4026-4033
出版商
American Society of Hematology
发表日期
2012-03-13
DOI
10.1182/blood-2011-07-365726
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL-driven leukemogenesis
- (2011) C. Albers et al. BLOOD
- Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways
- (2011) Siyuan Zhang et al. NATURE MEDICINE
- SRC hits the mark
- (2011) Darren J. Burgess NATURE REVIEWS DRUG DISCOVERY
- Oncogenic JAK2V617F requires an intact SH2-like domain for constitutive activation and induction of a myeloproliferative disease in mice
- (2010) S. P. Gorantla et al. BLOOD
- FLT3 as a therapeutic target in AML: still challenging after all these years
- (2010) T. Kindler et al. BLOOD
- Phase I/II Study of Combination Therapy With Sorafenib, Idarubicin, and Cytarabine in Younger Patients With Acute Myeloid Leukemia
- (2010) Farhad Ravandi et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-Risk Myelodysplastic Syndrome With Either Wild-Type or Mutated FLT3
- (2010) Thomas Fischer et al. JOURNAL OF CLINICAL ONCOLOGY
- Insertion of FLT3 internal tandem duplication in the tyrosine kinase domain-1 is associated with resistance to chemotherapy and inferior outcome
- (2009) S. Kayser et al. BLOOD
- AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)
- (2009) P. P. Zarrinkar et al. BLOOD
- Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality
- (2009) D. Schmidt-Arras et al. BLOOD
- Oncogenic signaling from the hematopoietic growth factor receptors c-Kit and Flt3
- (2009) Kristina Masson et al. CELLULAR SIGNALLING
- Oncogenic Flt3 receptors display different specificity and kinetics of autophosphorylation
- (2009) Elena Razumovskaya et al. EXPERIMENTAL HEMATOLOGY
- Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration
- (2009) Rebekka Grundler et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes
- (2009) Chunaram Choudhary et al. MOLECULAR CELL
- Flow cytometric determination of Src phosphorylation in pediatric patients treated with dasatinib
- (2009) Bella S. Guerrouahen et al. PEDIATRIC BLOOD & CANCER
- Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor
- (2008) F. Breitenbuecher et al. BLOOD
- Transformation by Oncogenic Mutants and Ligand-Dependent Activation of FLT3 Wild-type Requires the Tyrosine Residues 589 and 591
- (2008) S. Vempati et al. CLINICAL CANCER RESEARCH
- Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors
- (2008) H Konig et al. LEUKEMIA
- Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia
- (2008) Richard F. Schlenk et al. NEW ENGLAND JOURNAL OF MEDICINE
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now