Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
出版年份 2012 全文链接
标题
Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition
作者
关键词
-
出版物
BLOOD
Volume 120, Issue 17, Pages 3519-3529
出版商
American Society of Hematology
发表日期
2012-09-07
DOI
10.1182/blood-2012-03-416776
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- NAD depletion by FK866 induces autophagy
- (2014) Richard A. Billington et al. Autophagy
- Nicotinamide Phosphoribosyl Transferase/Pre-B Cell Colony-Enhancing Factor/Visfatin Is Required for Lymphocyte Development and Cellular Resistance to Genotoxic Stress
- (2014) A. Rongvaux et al. JOURNAL OF IMMUNOLOGY
- Guidelines for the use and interpretation of assays for monitoring autophagy
- (2012) Daniel J. Klionsky et al. Autophagy
- Targeting Autophagy Augments In Vitro and In Vivo Antimyeloma Activity of DNA-Damaging Chemotherapy
- (2011) Y. Pan et al. CLINICAL CANCER RESEARCH
- Principles and Current Strategies for Targeting Autophagy for Cancer Treatment
- (2011) R. K. Amaravadi et al. CLINICAL CANCER RESEARCH
- Synergistic Interactions between HDAC and Sirtuin Inhibitors in Human Leukemia Cells
- (2011) Michele Cea et al. PLoS One
- Compromising the Unfolded Protein Response Induces Autophagy-Mediated Cell Death in Multiple Myeloma Cells
- (2011) Anne-Sophie Michallet et al. PLoS One
- TFEB Links Autophagy to Lysosomal Biogenesis
- (2011) C. Settembre et al. SCIENCE
- A novel quantitative flow cytometry-based assay for autophagy
- (2010) Kai Er Eng et al. Autophagy
- Methods in Mammalian Autophagy Research
- (2010) Noboru Mizushima et al. CELL
- mTOR regulation of autophagy
- (2010) Chang Hwa Jung et al. FEBS LETTERS
- Dual Inhibition of Akt/Mammalian Target of Rapamycin Pathway byNanoparticle Albumin-Bound–Rapamycin and Perifosine Induces Antitumor Activity in Multiple Myeloma
- (2010) Diana Cirstea et al. MOLECULAR CANCER THERAPEUTICS
- Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity
- (2010) Douglas W McMillin et al. NATURE MEDICINE
- NAMPT overexpression in prostate cancer and its contribution to tumor cell survival and stress response
- (2010) B Wang et al. ONCOGENE
- Autophagy and Metabolism
- (2010) J. D. Rabinowitz et al. SCIENCE
- The NAD biosynthesis inhibitor APO866 has potent antitumor activity against hematologic malignancies
- (2009) A. Nahimana et al. BLOOD
- mTOR and cancer: many loops in one pathway
- (2009) Alejo Efeyan et al. CURRENT OPINION IN CELL BIOLOGY
- NAMPT is essential for the G-CSF–induced myeloid differentiation via a NAD+–sirtuin-1–dependent pathway
- (2009) Julia Skokowa et al. NATURE MEDICINE
- Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner
- (2009) Frédéric Van Gool et al. NATURE MEDICINE
- Catastrophic NAD+ Depletion in Activated T Lymphocytes through Nampt Inhibition Reduces Demyelination and Disability in EAE
- (2009) Santina Bruzzone et al. PLoS One
- Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1
- (2009) Y. Nakahata et al. SCIENCE
- Nicotinamide Adenine Dinucleotide Based Therapeutics
- (2008) K. Pankiewicz et al. CURRENT MEDICINAL CHEMISTRY
- Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
- (2008) Marcella Fulco et al. DEVELOPMENTAL CELL
- Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
- (2008) Michael Degtyarev et al. JOURNAL OF CELL BIOLOGY
- Nampt: linking NAD biology, metabolism and cancer
- (2008) Antje Garten et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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