Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Initial HIV-1 Antigen-Specific CD8+ T Cells in Acute HIV-1 Infection Inhibit Transmitted/Founder Virus Replication

(2012) S. A. Freel et al.   JOURNAL OF VIROLOGY

Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

(2011) T. Yamamoto et al.   BLOOD

Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development

(2011) Gerritje J.W. van der Windt et al.   IMMUNITY

A high-throughput single-cell analysis of human CD8+ T cell functions reveals discordance for cytokine secretion and cytolysis

(2011) Navin Varadarajan et al.   JOURNAL OF CLINICAL INVESTIGATION

Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells

(2011) Florentin-Martial Mbitikon-Kobo et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Clonotype and Repertoire Changes Drive the Functional Improvement of HIV-Specific CD8 T Cell Populations under Conditions of Limited Antigenic Stimulation

(2011) L. Janbazian et al.   JOURNAL OF IMMUNOLOGY

Why Don't CD8+ T Cells Reduce the Lifespan of SIV-Infected Cells In Vivo?

(2011) Marjet Elemans et al.   PLoS Computational Biology

Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection

(2011) Guido Ferrari et al.   PLoS Pathogens

Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival

(2010) T. W. Hand et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

(2010) Nichole R. Klatt et al.   PLoS Pathogens

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

(2009) Nilu Goonetilleke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunologic and Virologic Events in Early HIV Infection Predict Subsequent Rate of Progression

(2009) Anuradha Ganesan et al.   JOURNAL OF INFECTIOUS DISEASES

Metabolic control of T cell activation and death in SLE

(2008) David Fernandez et al.   AUTOIMMUNITY REVIEWS

Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses

(2008) Denis Gaucher et al.   JOURNAL OF EXPERIMENTAL MEDICINE