Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model

Loss of the wild-type allele contributes to myeloid expansion and disease aggressiveness in FLT3/ITD knockin mice

(2011) L. Li et al.   BLOOD

Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation

(2011) S. Kharazi et al.   BLOOD

NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern

(2011) I. H. I. M. Hollink et al.   BLOOD

Backtracking to birth of the NUP98-HOXD13 gene fusion in an infant acute myeloid leukemia

(2011) M Emerenciano et al.   LEUKEMIA

High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes

(2010) T Taketani et al.   LEUKEMIA

Acute myeloid leukemia with NUP98–HOXC13 fusion and FLT3 internal tandem duplication mutation: case report and literature review

(2009) Nataša Tos̆ić et al.   CANCER GENETICS AND CYTOGENETICS

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model

(2008) L. Li et al.   BLOOD

Myelodysplastic syndromes

(2008) S. D. Nimer   BLOOD

Mutant FLT3: A Direct Target of Sorafenib in Acute Myelogenous Leukemia

(2008) Weiguo Zhang et al.   JNCI-Journal of the National Cancer Institute