Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes

Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy

(2011) H. Wang et al.   BLOOD

Double-Stranded DNA Activates Glomerular Endothelial Cells and Enhances Albumin Permeability via a Toll-Like Receptor-Independent Cytosolic DNA Recognition Pathway

(2009) Holger Hägele et al.   AMERICAN JOURNAL OF PATHOLOGY

Hypercoagulability Inhibits Monocyte Transendothelial Migration Through Protease-Activated Receptor-1-, Phospholipase-Cβ-, Phosphoinositide 3-Kinase-, and Nitric Oxide-Dependent Signaling in Monocytes and Promotes Plaque Stability

(2009) Stefanie Seehaus et al.   CIRCULATION

Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1

(2009) Akanksha Gupta et al.   CURRENT DRUG TARGETS

Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity

(2009) Huang Guo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells

(2009) Zhihui Zhong et al.   JOURNAL OF CLINICAL INVESTIGATION

Proteases Display Biased Agonism at Protease-Activated Receptors: Location matters!

(2009) A. Russo et al.   MOLECULAR INTERVENTIONS

The protease-activated receptor-3 (PAR-3) can signal autonomously to induce interleukin-8 release

(2008) E. Ostrowska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipid raft localization regulates the cleavage specificity of protease activated receptor 1 in endothelial cells

(2008) J.-S. BAE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The actin cytoskeleton of kidney podocytes is a direct target of the antiproteinuric effect of cyclosporine A

(2008) Christian Faul et al.   NATURE MEDICINE

Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells

(2008) X. V. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA