Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

(2010) Áine C. Murphy et al.   BRAIN BEHAVIOR AND IMMUNITY

Peripheral Neuropathy in Chronic Obstructııve Pulmonary Dıısease

(2010) Çağğatay Öncel et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Kinase inhibitors: a new approach to rheumatoid arthritis treatment

(2010) Stanley Cohen et al.   CURRENT OPINION IN RHEUMATOLOGY

KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase

(2010) Antonio Garrido Montalban et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Kinetics of IL-17- and interferon-γ-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice

(2010) Harald H. Hofstetter et al.   NEUROSCIENCE LETTERS

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

Efficacy and safety of pamapimod in patients with active rheumatoid arthritis receiving stable methotrexate therapy

(2009) R E Alten et al.   ANNALS OF THE RHEUMATIC DISEASES

Efficacy, pharmacodynamics, and safety of VX-702, a novel p38 MAPK inhibitor, in rheumatoid arthritis: Results of two randomized, double-blind, placebo-controlled clinical studies

(2009) Nemanja Damjanov et al.   ARTHRITIS AND RHEUMATISM

T Cell Receptor-mediated Activation of p38α by Mono-phosphorylation of the Activation Loop Results in Altered Substrate Specificity

(2009) Paul R. Mittelstadt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Randomized, Placebo-Controlled Study of the Effects of the p38 MAPK Inhibitor SB-681323 on Blood Biomarkers of Inflammation in COPD Patients

(2009) Dave Singh et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Genetic disruption of p38  Tyr323 phosphorylation prevents T-cell receptor-mediated p38  activation and impairs interferon-  production

(2008) L. Jirmanova et al.   BLOOD

Systematic review to establish the safety profiles for direct and indirect inhibitors of p38 Mitogen-activated protein kinases for treatment of cancer

(2008) J. Kay Noel et al.   MEDICAL ONCOLOGY

Epigallocatechin-3-gallate suppresses TNF-α -induced production of MMP-1 and -3 in rheumatoid arthritis synovial fibroblasts

(2008) Hee-Jin Yun et al.   RHEUMATOLOGY INTERNATIONAL

The identification of a small molecule inhibitor that specifically reduces T cell-mediated adaptive but not LPS-mediated innate immunity by T cell membrane–monocyte contact bioassay

(2007) Yi-Yang Yvonne Li et al.   IMMUNOLOGY LETTERS