Identification of HIF2  as an important STAT5 target gene in human hematopoietic stem cells

Down-regulation of GATA1 uncouples STAT5-induced erythroid differentiation from stem/progenitor cell proliferation

(2010) A. T. J. Wierenga et al.   BLOOD

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Hypoxia-inducible proto-oncogene Pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma

(2010) Carolin Reiser-Erkan et al.   CANCER BIOLOGY & THERAPY

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

(2010) Tugba Simsek et al.   Cell Stem Cell

Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells

(2010) Keiyo Takubo et al.   Cell Stem Cell

Hypoxia-Mediated Up-Regulation of Pim-1 Contributes to Solid Tumor Formation

(2009) Jian Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis

(2009) A. Kimura et al.   BLOOD

Conditional deletion of STAT5 in adult mouse hematopoietic stem cells causes loss of quiescence and permits efficient nonablative stem cell replacement

(2009) Z. Wang et al.   BLOOD

Hierarchical Maintenance of MLL Myeloid Leukemia Stem Cells Employs a Transcriptional Program Shared with Embryonic Rather Than Adult Stem Cells

(2009) Tim C.P. Somervaille et al.   Cell Stem Cell

ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

(2009) Yifang Hu et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

(2009) Lina Han et al.   PLoS One

Human cancers converge at the HIF-2α oncogenic axis

(2009) Aleksandra Franovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Malignant Transformation Initiated by Mll-AF9: Gene Dosage and Critical Target Cells

(2008) Weili Chen et al.   CANCER CELL

Regulation of gene expression by hypoxia: Integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element

(2008) Stefan Kaluz et al.   CLINICA CHIMICA ACTA

Cancer induction by restriction of oncogene expression to the stem cell compartment

(2008) María Pérez-Caro et al.   EMBO JOURNAL

Mucin1 expression is enriched in the human stem cell fraction of cord blood and is upregulated in majority of the AML cases

(2008) Szabolcs Fatrai et al.   EXPERIMENTAL HEMATOLOGY

Maximal STAT5-Induced Proliferation and Self-Renewal at Intermediate STAT5 Activity Levels

(2008) A. T. J. Wierenga et al.   MOLECULAR AND CELLULAR BIOLOGY