Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1-expressing myeloma cells

Endogenous Noxa Determines the Strong Proapoptotic Synergism of the BH3-Mimetic ABT-737 with Chemotherapeutic Agents in Human Melanoma Cells

(2014) Arnim Weber et al.   Translational Oncology

BH3 response profiles from neuroblastoma mitochondria predict activity of small molecule Bcl-2 family antagonists

(2009) K C Goldsmith et al.   CELL DEATH AND DIFFERENTIATION

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins

(2009) Delphine Mérino et al.   JOURNAL OF CELL BIOLOGY

Bim Upregulation by Histone Deacetylase Inhibitors Mediates Interactions with the Bcl-2 Antagonist ABT-737: Evidence for Distinct Roles for Bcl-2, Bcl-xL, and Mcl-1

(2009) S. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Alterations in the Noxa/Mcl-1 axis determine sensitivity of small cell lung cancer to the BH3 mimetic ABT-737

(2009) P. Hauck et al.   MOLECULAR CANCER THERAPEUTICS

ABT-737 Synergizes with Chemotherapy to Kill Head and Neck Squamous Cell Carcinoma Cells via a Noxa-Mediated Pathway

(2009) R. Li et al.   MOLECULAR PHARMACOLOGY

Mimicking the BH3 domain to kill cancer cells

(2009) T Ni Chonghaile et al.   ONCOGENE

RNA Silencing of Mcl-1 Enhances ABT-737-Mediated Apoptosis in Melanoma: Role for a Caspase-8-Dependent Pathway

(2009) Angela M. Keuling et al.   PLoS One

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

(2008) A. A. Morales et al.   BLOOD

Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors

(2008) K. F. Whitecross et al.   BLOOD

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

Therapeutic Efficacy of ABT-737, a Selective Inhibitor of BCL-2, in Small Cell Lung Cancer

(2008) C. L. Hann et al.   CANCER RESEARCH

Induction of Noxa Sensitizes Human Colorectal Cancer Cells Expressing Mcl-1 to the Small-Molecule Bcl-2/Bcl-xL Inhibitor, ABT-737

(2008) K. Okumura et al.   CLINICAL CANCER RESEARCH

Involvement of BH3-only proteins in hematologic malignancies

(2008) Junya Kuroda et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Identification of the Major Phosphorylation Site in Bcl-xL Induced by Microtubule Inhibitors and Analysis of Its Functional Significance

(2008) Meenakshi Upreti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Converting cell lines representing hematological malignancies from glucocorticoid-resistant to glucocorticoid-sensitive: Signaling pathway interactions

(2008) Anna S. Garza et al.   LEUKEMIA RESEARCH

Multisite Phosphorylation Regulates Bim Stability and Apoptotic Activity

(2008) Anette Hübner et al.   MOLECULAR CELL