Article
Biochemistry & Molecular Biology
Amit Kumar Sharma, Ankita Dhiman, Amit Kumar Nayak, Rishabh Mishra, Garima Agrawal
Summary: In this study, gelatin/kappa-carrageenan crosslinked polyacrylic acid hydrogel and graphene oxide incorporated hydrogel nanocomposite were synthesized and characterized. The adsorption performance of these hydrogel materials was investigated, and they showed good adsorption capacity for dyes removal.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Medicine, Research & Experimental
Mona H. Zohny, Simona Cavalu, Mahmoud E. Youssef, Mohamed M. Y. Kaddah, Ahmed A. E. Mourad, Ahmed Gaafar Ahmed Gaafar, Eman El-Ahwany, Noha A. Amin, Heba M. Arakeep, Ahmed Shata, Safaa Saleh, Mohamed M. Hafez, Sara T. Elazab, Rasha Abdelhady, Rehab Mohamed El Shahat, Galal Yahya, Sameh Saber
Summary: CBBG effectively inhibited pulmonary fibrosis and inflammation in a rat model. It exerted lung-protective effects by inactivating NLRP3 inflammasome and NF-kappa B, suggesting its potential clinical applications in the treatment of pulmonary fibrosis.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Engineering, Chemical
Hongbo Wang, Huaran Xing, Kuangqi Yan, Duiwen Han, Jingdi Chen
Summary: Discharging of dyestuff is a significant cause of water pollution. In this study, hydroxyapatite microspheres prepared from oyster shell wastes were used to mimic the removal of Coomassie brilliant blue (CBB) in wastewater. Factors such as solution pH, initial CBB concentration, and temperature were investigated to determine their effects on the adsorption capacity. The results showed that the hydroxyapatite microspheres exhibited strong adsorption capacity for CBB and could be reused effectively.
ADVANCED POWDER TECHNOLOGY
(2022)
Article
Chemistry, Physical
Umit Ecer, Sakir Yilmaz, Tekin Sahan
Summary: In this study, silver nanoparticles (AgNPs) supported on mercapto-functionalized clay were used for the decolorization of Coomassie brilliant blue (CBB). The effects of four parameters (NaBH4 amount, CBB concentration, time, and catalyst amount) on the decolorization efficiency and the optimization of the process were investigated. Under the optimum conditions, a decolorization efficiency of 97.73% for CBB was achieved. The kinetic and thermodynamic results indicated that the decolorization rate increased with temperature and the process was endothermic and favorable.
CHEMICAL PHYSICS LETTERS
(2023)
Article
Engineering, Environmental
Azhan Ahmad, Monali Priyadarshini, Shraddha Yadav, Makarand M. Ghangrekar, Rao Y. Surampalli
Summary: In this study, a waste medicine wrapper made of aluminium metal was used in the electrocoagulation (W-EC) process to treat Coomassie brilliant blue (CBB) dye wastewater. The results showed that under optimal conditions, including a current density of 2.1 mA/cm2, pH of 7.0, 1 g/L of NaCl, charge loading of 129.6 C/L, and electrode gap of 1.5 cm, a decolourization efficiency of 96.7 ± 2.2% for 25 mg/L of CBB dye was achieved during a 15-minute electrolysis period. The removal of dye followed first-order rate kinetics with a rate constant of 0.35 min-1 and an electrical energy consumption of 0.15 kWh/m3. Additionally, significant removals of chemical oxygen demand and total organic carbon were also observed. The utilization of waste medicine wrappers as electrodes in the EC process not only provides a sustainable solution for waste management but also reduces treatment costs.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Jiangpeng Hu, Bo Teng, Zhipeng Xu, Yuanye Wan, Guofan Jin
Summary: Four distinct fluorescence complexes were created using isorhamnetin and Coomassie brilliant blue G250 as raw materials, effectively addressing the issue of isorhamnetin's low solubility. These complexes demonstrated good biocompatibility and strong anti-tumor properties, with FC-1 showing high selectivity and accurate infiltration into tumor cells.
FRONTIERS IN CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Marwa S. Salem, Ahmed R. Wassel, M. Fedawy, A. Shaker, Amal H. Al-Bagawia, Ghada Mohamed Aleid, Ahmed M. El-Mahalawy
Summary: This study systematically investigated the structural, morphological, and optical properties of solution-processed coomassie brilliant blue (CBB) thin films for photodetection applications, revealing promising performance and stability. The fabricated heterojunction showed good figures of merit and stable response behavior, making it a potential candidate for photodetection applications.
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
(2022)
Article
Chemistry, Applied
Jingke Xu, Leina Dou, Sijie Liu, Lihong Su, Xuechi Yin, Jing Ren, Huilan Hu, Daohong Zhang, Jing Sun, Zhanhui Wang, Jianlong Wang
Summary: A novel method was developed for detecting FZD, utilizing the CBB-LFIA strategy which is simple, stable, and cost-effective. It can rapidly detect AOZ with a high detection limit, showing great practical application and utilization potential in the related field.
Article
Environmental Sciences
Jilda Sofiana Buhani, Jilda Sofiana Dewi, Nadya Syarifatul Fajriyah, Mita Z. Rilyanti, Suharso, Sumadi, Khalid Elwakeel
Summary: This study modified carbon derived from rubber fruit shells, resulting in nAC-RFs-S through the use of a silane agent called 3-Aminopropyl-Triethoxysilane (APTES). The adsorbent was characterized using Infrared Spectrometer (IR) and Scanning Electron Microscopy-Energy Dispersive-X-ray (SEM-EDX). Batch adsorption experiments showed that nAC-RFs-S had optimal conditions for adsorbing Coomassie Brilliant Blue (CBB) and Methylene Blue (MB) dyes. The nAC-RFs-S adsorbent demonstrated remarkable effectiveness in adsorbing CBB and MB in solution, with the ability to be reused for multiple cycles.
WATER AIR AND SOIL POLLUTION
(2023)
Article
Engineering, Chemical
Jin Zhao, Qing-Xi Wu, Xiao-Du Cheng, Ting Su, Xiao-Hui Wang, Wen-Na Zhang, Yong-Ming Lu, Yan Chen
Summary: The mycelia of Lactarius deliciosus showed excellent capability in decolorizing CBB, with high removal rates and good re-usability. Enzymes involved in the degradation process were verified, and toxicity assessments indicated minimal impact on seed germination and bacterial growth. The removal of CBB was achieved through a synergistic process of adsorption and biodegradation.
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Mingjun Yang, Dongxiang Shi, Yonggang Wang, Abdol Ghaffar Ebadi, Mohsen Toughani
Summary: The study investigated the interaction of CBBG-250 with BSA through multispectroscopic methods. It was found that the two can form a stable complex through hydrogen bonds and Van der Waals forces. The diphenylamine structure in CBBG-250 and the amino acid residues play a significant role in the interaction.
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2021)
Article
Chemistry, Analytical
Liliya Gimadutdinova, Guzel Ziyatdinova, Rustam Davletshin
Summary: The study developed a sensing platform for the electrochemical detection of synthetic dyes, tartrazine and brilliant blue FCF, using a glassy carbon electrode modified with MnO2 nanorods. The sensor showed high selectivity and stability, allowing simultaneous quantification of the dyes in various samples. The determined concentrations of the dyes in soft and isotonic sports drinks were close to those obtained using chromatography.
Article
Chemistry, Analytical
Kenichiro Nagata, Ryo Ashikaga, Wakako Mori, Tamotsu Zako, Youji Shimazaki
Summary: Researchers have developed a method for separating and evaluating lysozyme fibrils and their enzymatic degradation products, which can be applied to investigate the enzymatic degradation process of amyloid fibrils.
ANALYTICAL SCIENCES
(2023)
Article
Ophthalmology
Kaku Itoh
Summary: This study evaluated the stainability of several acrylic intraocular lenses (IOLs) with Brilliant Blue G (BBG) in vitro. The results showed that all acrylic IOLs can be stained with BBG, with hydrophilic IOLs being more susceptible to staining. Precautions should be taken in surgeries requiring the use of BBG staining, and efforts should be made to ensure sufficient intraoperative washing of the dye.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Nikson Fatt-Ming Chong, Hasnain Hussain, Nur Ezzati Hamdin, David Hong-Sheng Wee, Mehvish Nisar, Wei-Jie Yan, Benjamin Yii Chung Lau, Norasfaliza Rahmad
Summary: This article describes an improved colloidal CBB-G staining method that enhances the resolution of protein bands by adding a fixation step. The modification is fast, flexible, and improves protein visualization in SDS-PAGE.
CHEMICAL AND BIOLOGICAL TECHNOLOGIES IN AGRICULTURE
(2022)
Article
Biochemistry & Molecular Biology
Dimitrios N. Zisimopoulos, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, Nikolaos T. Panagopoulos, Georgios Salahas, Christos D. Georgiou
Summary: The study introduces a new method for quantification of 2-hydroxyethidium, showcasing innovations in efficient extraction and sensitive quantification protocols. This method can be applied to most biological systems for accurate detection.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Panagiotis Svarnas, Michael Poupouzas, Konstantia Papalexopoulou, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, Athina Varemmenou, Evangelos Giannakopoulos, Christos D. Georgiou, Stavroula Georga, Christoforos Krontiras
Summary: This work focuses on the treatment of unbuffered and buffered water using atmospheric pressure cold plasma. The activation of these liquids by plasma-induced chemistry has potential applications in various fields. The study measures various properties of the treated liquids and investigates the reactions occurring in the plasma. The experimental results are compared with previous studies in a concise review.
APPLIED SCIENCES-BASEL
(2022)
Article
Biochemistry & Molecular Biology
George I. Habeos, Fotini Filippopoulou, Evagelia E. Habeos, Electra Kalaitzopoulou, Marianna Skipitari, Polyxeni Papadea, George Lagoumintzis, Athanasios Niarchos, Christos D. Georgiou, Dionysios V. Chartoumpekis
Summary: This study found that calorie restriction during pregnancy can induce the expression of antioxidant genes in the fetal liver, and this induction is at least partially dependent on the Nrf2 signaling pathway. This finding highlights the importance of further investigating the physiological significance of this phenomenon.
Article
Medicine, General & Internal
Polyxeni Papadea, Marianna Skipitari, Electra Kalaitzopoulou, Athina Varemmenou, Maria Spiliopoulou, Marios Papasotiriou, Evangelos Papachristou, Dimitrios Goumenos, Anny Onoufriou, Eleftheria Rosmaraki, Irene Margiolaki, Christos D. Georgiou
Summary: The present study uses simple, innovative methods to isolate, characterize, and fractionate LDL in its main components for the study of specific oxidations on them. It aims to understand the oxidized low-density lipoprotein (oxLDL) status and its relation to cardiovascular disease (CVD) risk assessment. The study provides protocols for LDL isolation, purity verification, fractionation, and measurement of specific LDL component oxidative modifications, which can help in studying atherosclerosis and developing CVD prevention strategies.
FRONTIERS IN MEDICINE
(2023)
Article
Environmental Sciences
Katie O'Rourke, Christina Virgiliou, Georgios Theodoridis, Helen Gika, Konstantinos Grintzalis
Summary: Pharmaceuticals are considered emerging contaminants in the aquatic ecosystem due to increased use and improper disposal. These compounds have been detected in surface waters worldwide and have detrimental effects on non-target organisms. Analytical approaches for detecting pharmaceutical pollution are limited by sensitivity and coverage, but effect-based methods provide mechanistic insight. This study evaluated the acute effects of antibiotics, estrogens, and other common pharmaceutical pollutants on daphnids in freshwater ecosystems, finding distinct patterns in biological responses. Enzyme changes and metabolite up-regulation were observed following exposure to certain pharmaceuticals.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
(2023)
Article
Surgery
Apostolos Angelis, Ioannis D. Kostakis, Konstantinos Lilimpakis, Electra Kalaitzopoulou, Polyxeni Papadea, Marianna Skipitari, Christos D. Georgiou, Costas Vagianos
Summary: This study investigated the effects of obstructive jaundice on intestinal permeability and markers of oxidative stress in blood and intestinal mucosa. The results showed that obstructive jaundice increases oxidative stress and alters liver function. These findings provide insight into the pathophysiology of obstructive jaundice.
EUROPEAN SURGICAL RESEARCH
(2023)
Article
Biochemistry & Molecular Biology
N. Arul Manikandan, Ronan McCann, Dimitrios Kakavas, Keith D. Rochfort, Sithara P. Sreenilayam, Godze Alkan, Tom Stornetta, Allan Robert McGivern, Konstantinos Grintzalis, Bernd Friedrich, Greg Foley, Dermot Brabazon, Brian Freeland
Summary: Food spoilage leads to increased carbon dioxide emissions and food processing demand. This study developed anti-bacterial coatings using inkjet printing of silver nano-inks on food-grade polymer packaging, aiming to enhance food safety and reduce spoilage. Silver nanoparticles were synthesized and characterized, and all silver nanoparticles showed strong antibacterial activity against E. coli. The printed silver nano-inks on polymer reduced the bacterial cell population, and the bactericidal performance was comparable to penicillin-coated polymer. Ecotoxicity testing on daphniids showed the impact on freshwater environment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Katie O'Rourke, Beatrice Engelmann, Rolf Altenburger, Ulrike Rolle-Kampczyk, Konstantinos Grintzalis
Summary: Pharmaceutical compounds, along with pesticides, heavy metals, and personal care products, are emerging contaminants that pose a major concern for aquatic ecosystems. The presence of pharmaceuticals can affect both freshwater organisms and human health through non-target effects and contamination of drinking water sources. This study explored the molecular and phenotypic alterations of commonly found pharmaceuticals in aquatic environments in daphnids, finding changes in enzyme activities and metabolic perturbations. Chronic exposure to low concentrations of pharmaceuticals resulted in significant alterations in metabolic and physiological endpoints.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Anna Michalaki, Konstantinos Grintzalis
Summary: This study assessed the impact of two commonly prescribed non-steroidal anti-inflammatory drugs on Daphnia magna, a species commonly found in freshwater ecosystems. It found that exposure to these drugs affected feeding behavior and key enzyme activities in the daphnids, and the effects were more pronounced in the transgenerational exposures. The study suggests that combining molecular and phenotypic markers of physiology in transgenerational studies is an effective way to understand the impact of pharmaceutical stressors.
Article
Biology
Yongda Li, David A. Collins, Konstantinos Grintzalis
Summary: The search for life on other planets relies on the detection of biosignatures of life. Many macromolecules have been suggested as potential targets, among which are proteins that are considered vital components of life. The study optimized a Bradford-based assay to quantify protein extracted from a Martian soil simulant, achieving high sensitivity and reproducibility. The method's applicability was explored, including the stability of the reagent, making it possible for future planetary exploration missions.
Article
Biochemical Research Methods
Anna Michalaki, Konstantinos Grintzalis
Summary: Medicinal and herbal plants are rich sources of biologically active phytochemicals, but comprehensive methods to accurately assess their composition and antioxidant properties are lacking. This study developed a multiparametric protocol with eight assays to quantify major phytochemical categories and their antioxidant potential. The protocol offers advantages of higher sensitivity and lower cost compared to commercial kits. Testing on herbal and medicinal plants demonstrated its effectiveness in characterising phytochemical composition. The modular design allows adaptation to different spectrophotometric instruments and the assays are simple to follow with minimal steps.
METHODS AND PROTOCOLS
(2023)
Article
Astronomy & Astrophysics
Christos D. Georgiou, Christopher McKay, Jean-Louis Reymond
Summary: In this study, a nearly ideal life detection instrument based on catalytic activity is proposed, which has high sensitivity but is insensitive to abiotic processes and can detect life with alternate molecular structures. The advantages of catalysis as an agnostic life detection method are demonstrated, including not requiring culturing/growing the alien life and large amplification by catalysis even in dead biomass. A hydrolytic catalysis detection instrument using chromogenic assay-based detection of various hydrolytic catalytic activities is specifically proposed, which can be used to detect activity in samples of extraterrestrial organic material from unknown life.
Article
Engineering, Environmental
Konstantinos Panagiotidis, Beatrice Engelmann, Martin Krauss, Ulrike E. Rolle-Kampczyk, Rolf Altenburger, Keith D. Rochfort, Konstantinos Grintzalis
Summary: Plastic waste poses a significant threat to terrestrial, marine, and freshwater ecosystems. The ingestion of microplastic particles resulting from plastic degradation can have serious health effects on organisms. This study investigated the effect of amine and carboxy functionalized polystyrene microparticles on the physiology of daphnids. The findings suggest that these microparticles can hinder organism performance and highlight the importance of using holistic and physiological endpoints for pollution assessment.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Polyxeni Papadea, Electra Kalaitzopoulou, Marianna Skipitari, Athina Varemmenou, Marios Papasotiriou, Evangelos Papachristou, Dimitrios Goumenos, Tilman Grune, Christos D. Georgiou
Summary: Maintenance peritoneal dialysis (PD) is associated with cardiovascular diseases (CVDs), assessed via LDL-C. This study measures six novel oxLDL markers in atherosclerosis-prone PD patients, chronic kidney disease patients under hemodialysis (HD) and healthy controls. The levels of all oxLDL lipid-OOH markers were significantly elevated in PD patients versus control, while the levels of cholesteryl ester-/triglyceride-/free cholesterol-OOH were significantly elevated in PD versus HD patients. The study suggests the potential prognostic value of oxLDL regarding CVD risk assessment.
Article
Biology
Yongda Li, Keith D. Rochfort, David Collins, Konstantinos Grintzalis
Summary: The study presents a comparison of optimized protocols for the quantification of DNA using common intercalator dyes, allowing for fast and accurate detection. The methods were successfully applied to DNA detection in soil samples.
Article
Biochemical Research Methods
Saranya Krishnan, Shina Sasi, Preshobha Kodakkattumannil, Salima Al Senaani, Geetha Lekshmi, Martin Kottackal, Khaled M. A. Amiri
Summary: This study aimed to develop an efficient DNA extraction protocol suitable for diverse plant species and tissues. A reliable and consistent protocol was described for the extraction of high-quality DNA from difficult-to-extract plant species. The optimized protocol was successful in extracting high-quality DNA from various plant species and tissues, making it useful for genomic studies of recalcitrant plants.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Eisaku Hokazono, Saori Fukumoto, Takeshi Uchiumi, Susumu Osawa
Summary: This study proposes a method for detecting nucleic acid amplification using pyrophosphate, which requires only two reagents and an automated analyzer. The technique has high sensitivity and reproducibility, and can detect pyrophosphate within 10 minutes. Therefore, this method has the potential to be a new, rapid, and simple detection technique for amplified nucleic acids.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Drew S. Sowersby, L. Kevin Lewis
Summary: SURE electrophoresis is a new method for concentrating samples in gels, which allows efficient detection of highly dilute DNA samples. This approach generates single bands with enhanced signal intensities and minimal band broadening.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Hongyi Liang, Guoliang Yin, Guangxi Shi, Zhiyong Liu, Xiaofei Liu, Jingwei Li
Summary: The mechanism of Echinacoside (ECH) in treating breast cancer (BC) was explored through network pharmacology and experimental validation. It was found that ECH plays an important role in anti-BC by regulating the PI3K/AKT/HIF-1 alpha/VEGF signaling pathway, and it exhibits multi-target and multi-pathway effects.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Daniel S. Kantner, Emily Megill, Anna Bostwick, Vicky Yang, Carmen Bekeova, Alexandria Van Scoyk, Erin L. Seifert, Michael W. Deininger, Nathaniel W. Snyder
Summary: This study compared the results of different methods for measuring the amount of acetyl-Coenzyme A. The colorimetric ELISA kit did not produce interpretable results, while the fluorometric enzymatic kit showed comparable results to the LC-MS-based methods depending on the matrix and extraction conditions. LC-MS/MS and LC-HRMS methods produced well-aligned results, especially when using stable isotope-labeled internal standards.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Jingyan Xu, Hanying Tan, Xionghui Ma, Linjing Su, Zhi Zhang, Yuhao Xiong
Summary: This study investigates the co-catalytic capabilities of MoO3 nanosheets in enhancing the enzyme-like catalytic activity of a two-dimensional ultrathin Fe(III)-modified covalent triazine framework (Fe-CTF) under neutral pH conditions. The Fe-CTF/MoO3 co-catalytic system exhibits enzyme-mimicking activity and enables the development of a colorimetric method for glucose detection. Furthermore, a straightforward one-pot colorimetric method is established for screening XOD inhibitors.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Lichao Zhang, Kang Xiao, Xueting Wang, Liang Kong
Summary: A novel fusion technology was designed to identify FAD-binding sites, achieving the best results on two independent test datasets and outperforming existing methods significantly. The high performance and certainty of the method were demonstrated through statistical tests and cross-entropy loss analysis.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Abdulkadir Kilic, Mehmet Aslan, Abdulkadir Levent
Summary: This study developed a simple, rapid, sensitive, and selective voltammetric technique for the electrochemical characterization and detection of the highly risky drug Edoxaban. The optimized voltammetric method showed good analytical working range and was successfully applied to urine and tablet samples.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Su Hyun Kim, Nara Shin, Jong-Min Jeon, Jeong-Jun Yoon, Jeong Chan Joo, Hee Taek Kim, Shashi Kant Bhatia, Yung-Hun Yang
Summary: To address environmental issues caused by traditional plastics, bioplastics have gained attention as alternatives. Although bioplastics have better degradability, their degradation still takes longer than anticipated. This study proposes a novel screening method to identify bioplastic degraders faster, saving time and providing more quantitative data.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Irem Okman Kocoglu, Pinar Esra Erden, Esma Kilic
Summary: In this study, an electrochemical biosensor based on carbon nanofibers and ionic liquid modification was constructed for tyramine detection. The biosensor showed linear response, low detection limit, high sensitivity, and exhibited good reproducibility, stability, and anti-interference ability.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Liana U. Akhmetzianova, Timur M. Davletkulov, Assol R. Sakhabutdinova, Alexey Chemeris, Irek M. Gubaydullin, Ravil R. Garafutdinov
Summary: A new program called LAMPrimers iQ has been developed for high-quality LAMP primer design, and its advantages in providing higher specificity and reliable detection of viral RNA were validated using SARS-CoV-2 coronavirus RNA as a model target.
ANALYTICAL BIOCHEMISTRY
(2024)
Article
Biochemical Research Methods
Tommaso Pileri, Alberto Sinibaldi, Agostino Occhicone, Norbert Danz, Elena Giordani, Matteo Allegretti, Frank Sonntag, Peter Munzert, Patrizio Giacomini, Francesco Michelotti
Summary: This study developed a biosensing device based on one-dimensional photonic crystal to detect HER2 in breast cancer. The device combines label-free and fluorescence operation modes, allowing for real-time and accurate detection in less than 20 minutes. It offers a promising technique for combined label-free and fluorescence detection in disease diagnosis and therapeutic monitoring.
ANALYTICAL BIOCHEMISTRY
(2024)
