The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia

Inactivation of LEF1 in T-cell acute lymphoblastic leukemia

(2010) A. Gutierrez et al.   BLOOD

Absence of Biallelic TCRγ Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia

(2010) Alejandro Gutierrez et al.   JOURNAL OF CLINICAL ONCOLOGY

ATM-deficient thymic lymphoma is associated with aberranttcrdrearrangement and gene amplification

(2010) Shan Zha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The TLX1 oncogene drives aneuploidy in T cell transformation

(2010) Kim De Keersmaecker et al.   NATURE MEDICINE

Reprogramming of T Cells to Natural Killer-Like Cells upon Bcl11b Deletion

(2010) P. Li et al.   SCIENCE

An Early T Cell Lineage Commitment Checkpoint Dependent on the Transcription Factor Bcl11b

(2010) L. Li et al.   SCIENCE

An Essential Developmental Checkpoint for Production of the T Cell Lineage

(2010) T. Ikawa et al.   SCIENCE

High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

(2009) A. Gutierrez et al.   BLOOD

Haploinsufficiency and acquired loss ofBcl11bandH2AXinduces blast crisis of chronic myelogenous leukemia in a transgenic mouse model

(2009) Akiko Nagamachi et al.   CANCER SCIENCE

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

(2009) Elaine Coustan-Smith et al.   LANCET ONCOLOGY

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

(2008) Pieter Van Vlierberghe et al.   BRITISH JOURNAL OF HAEMATOLOGY

Cooperative genetic defects in TLX3 rearranged pediatric T-ALL

(2008) P Van Vlierberghe et al.   LEUKEMIA