Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

The HBS1L-MYB intergenic interval associated with elevated HbF levels shows characteristics of a distal regulatory region in erythroid cells

(2009) K. Wahlberg et al.   BLOOD

BCL11A represses HBG transcription in K562 cells

(2009) Zhiyi Chen et al.   BLOOD CELLS MOLECULES AND DISEASES

Genetic architecture of hemoglobin F control

(2009) Stephan Menzel et al.   CURRENT OPINION IN HEMATOLOGY

Variation and heritability of Hb F and F-cells among β-thalassemia heterozygotes in Hong Kong

(2008) Geoffrey T. Gibney et al.   AMERICAN JOURNAL OF HEMATOLOGY

Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease

(2008) A. E. Ashley-Koch et al.   BLOOD

BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

(2008) Amanda E. Sedgewick et al.   BLOOD CELLS MOLECULES AND DISEASES

Locus control region mediated regulation of adult β-globin gene expression

(2008) Shermi Liang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of  -thalassemia

(2008) M. Uda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTCF-dependent enhancer-blocking by alternative chromatin loop formation

(2008) C. Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific RepressorBCL11A

(2008) Vijay G. Sankaran et al.   SCIENCE

Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations

(2007) Paola Sebastiani et al.   AMERICAN JOURNAL OF HEMATOLOGY