The role of substrate binding pocket residues phenylalanine 176 and phenylalanine 196 onPseudomonassp. OX1 tolueneo-xylene monooxygenase activity and regiospecificity

Crystallographic Analysis of Active Site Contributions to Regiospecificity in the Diiron Enzyme Toluene 4-Monooxygenase

(2012) Lucas J. Bailey et al.   BIOCHEMISTRY

Biocatalyst development by directed evolution

(2012) Meng Wang et al.   BIORESOURCE TECHNOLOGY

Directed enzyme evolution: beyond the low-hanging fruit

(2012) Moshe Goldsmith et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

RECENT ADVANCES IN RATIONAL APPROACHES FOR ENZYME ENGINEERING

(2012) Kerstin Steiner et al.   Computational and Structural Biotechnology Journal

Tuning the Specificity of the Recombinant Multicomponent Tolueneo-Xylene Monooxygenase from Pseudomonas sp. Strain OX1 for the Biosynthesis of Tyrosol from 2-Phenylethanol

(2011) Eugenio Notomista et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Analysis of Substrate Access to Active Sites in Bacterial Multicomponent Monooxygenase Hydroxylases: X-ray Crystal Structure of Xenon-Pressurized Phenol Hydroxylase fromPseudomonassp. OX1

(2011) Michael S. McCormick et al.   BIOCHEMISTRY

Tracking a defined route for O2 migration in a dioxygen-activating diiron enzyme

(2011) W. J. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Beyond directed evolution—semi-rational protein engineering and design

(2010) Stefan Lutz   CURRENT OPINION IN BIOTECHNOLOGY

Protein engineering of microbial enzymes

(2010) Dominique Böttcher et al.   CURRENT OPINION IN MICROBIOLOGY

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

In the light of directed evolution: Pathways of adaptive protein evolution

(2009) J. D. Bloom et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Determinants of the Regioselectivity of Toluene/o-Xylene Monooxygenase from Pseudomonas sp. Strain OX1

(2008) E. Notomista et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Molecular approaches in bioremediation

(2008) Thomas K Wood   CURRENT OPINION IN BIOTECHNOLOGY