Editorial Material
Multidisciplinary Sciences
Felicia Kuperwaser, Itai Yanai
Summary: A comprehensive cell atlas of gene expression and regulation in human embryos has provided a unique opportunity for innovative investigation of development through multi-organ and multi-modal analysis.
Editorial Material
Multidisciplinary Sciences
Fahad Rashid, James Berger
Summary: High-resolution structures of bacterial Rho protein in complex with an RNA polymerase enzyme and partner proteins confirm the long-held model of Rho's role in gene transcription termination.
Editorial Material
Multidisciplinary Sciences
Pavel V. Baranov, John F. Atkins
Summary: Messenger RNA has 64 possible codons, three of which usually stop protein synthesis. However, certain organisms can utilize all codons to determine amino acids, partially due to an unexpected characteristic of transfer RNA.
Review
Food Science & Technology
Mingqi Zhao, Miao Wang, Xiaoguang Zhang, Yongan Zhu, Jing Cao, Yongxin She, Zhen Cao, Guangyue Li, Jing Wang, A. M. Abd El-Aty
Summary: Excessive use of pesticides poses a serious threat to the environment and human health. Rapid detection of pesticide residues in food is crucial, and recognition elements play a key role in sensors and testing methods. Improper recognition elements can lead to method defects. Molecular biological techniques provide an effective strategy for addressing these challenges. This review summarizes the molecular biological methods for five specific recognition elements and discusses their application in conjunction with biosensors and immunoassays.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Editorial Material
Multidisciplinary Sciences
Ronald Cutler, Jan Vijg
Summary: The study has shown that radiation-damaged paternal DNA causes embryos of the second generation of nematode worms, but not the first, to die. The proposed mechanisms explain why this effect is not observed in humans.
Editorial Material
Multidisciplinary Sciences
Alexander Goedel, Fredrik Lanner
Summary: The molecular mechanisms involved in human gastrulation, a crucial stage in early embryonic development, have been largely elusive, but gene-expression data from a gastrulating human embryo shed light on this process.
Editorial Material
Multidisciplinary Sciences
Orsolya Barabas, Phoebe A. A. Rice
Summary: CRISPR-Cas is a bacterial defense system that can either protect host cells by attacking invading DNA or assist in the safe insertion of DNA into the genome. The structures of this specific type of CRISPR-Cas system have been successfully visualized.
Review
Biotechnology & Applied Microbiology
Sha Liu, Kaixuan Zhao, Meiyuan Huang, Meimei Zeng, Yan Deng, Song Li, Hui Chen, Wen Li, Zhu Chen
Summary: The global burden of foodborne disease is significant, with foodborne pathogens being the primary cause. The detection of foodborne pathogenic bacteria has rapidly developed in recent years, with methods such as immunoassay, molecular biology, microfluidic chip, metabolism, biosensor, and mass spectrometry being the main techniques. This study provides a comprehensive review of various rapid detection methods and discusses their limitations, advantages, and future development direction for accurate and rapid diagnosis and control of diseases in point-of-care testing (POCT) applications.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Editorial Material
Multidisciplinary Sciences
Leonid A. Mirny
Summary: The study reveals that loop extrusion, essential for chromosome folding and function, also plays a crucial part in repairing double-strand DNA breaks.
Editorial Material
Multidisciplinary Sciences
Maggie P. Lauria Sneideman, Victoria H. Meller
Summary: A protein that upregulates gene expression of the X chromosome has been discovered in male mosquitoes, which is crucial for equalizing gene expression between sexes in organisms with X and Y chromosomes.
Editorial Material
Multidisciplinary Sciences
David Lara-Astiaso, Brian J. P. Huntly
Summary: UTX protein regulates chromatin by condensing into liquid-like droplets, thereby suppressing tumor growth.
Editorial Material
Multidisciplinary Sciences
Alison Abbott
Summary: Researchers are interested in understanding the reasons behind cell secretion of vesicles and the functions of these vesicles during delivery.
Review
Microbiology
Wen-Feng Cao, Er-Ling Leng, Shi-Min Liu, Yong-Liang Zhou, Chao-Qun Luo, Zheng-Bing Xiang, Wen Cai, Wei Rao, Fan Hu, Ping Zhang, An Wen
Summary: Tuberculous meningitis is the most common and deadly type of central nervous system tuberculosis. Early diagnosis is crucial for patient prognosis, but laboratory diagnosis is challenging. This review summarizes the latest research in microbiological and molecular diagnostics for tuberculous meningitis and discusses issues related to diagnostic effectiveness, laboratory infrastructure, testing costs, and clinical expertise.
FRONTIERS IN MICROBIOLOGY
(2023)
Review
Chemistry, Applied
Yuanmiao Wei, Ling Li, Yao Liu, Shuna Xiang, Hanyue Zhang, Lunzhao Yi, Ying Shang, Wentao Xu
Summary: Edible fungi have great potential but confusion and food-borne diseases are common due to misidentification. Different detection methods based on substances in edible fungi include sensory identification, instrumental analysis, and molecular biology identification methods. Understanding the principles and applications of these techniques is crucial for accurate identification and food safety.
Editorial Material
Multidisciplinary Sciences
Marina. G. G. Guenza
Summary: Many biological processes rely on protein aggregates that have dynamic behaviors spanning different scales. A clever combination of spectroscopy and simulation can be used to investigate these diverse dynamics.
