期刊
BIOSENSORS & BIOELECTRONICS
卷 59, 期 -, 页码 134-139出版社
ELSEVIER ADVANCED TECHNOLOGY
DOI: 10.1016/j.bios.2014.03.029
关键词
Naringin-copper; Superoxide; Electrochemical sensor; Platinum electrode; Non-enzymatic sensor
类别
资金
- Department of Science & Technology, Government of India [SR/SO/BB-35/2004, DST/TSG/PT/2008/28]
- DST inspire fellowship [DST/IF/120812]
Flavonoid-metal ion complexes are a new class of molecules that have generated considerable interest due to their superior anti-oxidant and pharmacological activities. The metal ion present in these complexes can participate in redox reactions by toggling between different oxidation states. This property can be invaluable for sensing applications. But, the use of flavonoid-metal ion complexes as sensors remains an unexplored facet. The present work attempts to develop a non-enzymatic superoxide sensor using naringin-copper complex. Detection of superoxide has been mainly based on enzymes and cytochromes. However, these sensors are limited by their poor structural stability and high cost. The naringin-copper based non-enzymatic sensor exhibits good sensitivity in a range of 02-4.2 mu M with a response time of < 1 s. The performance of the sensor is not affected by pH and common interferents. (C) 2014 Elsevier B.V. All rights reserved.
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