Article
Biochemical Research Methods
Yan Liu, Ke Wang, Xiaohao Sun, Deyong Chen, Junbo Wang, Jian Chen
Summary: This study presented a microfluidic platform that characterizes single-cell biomechanical and bioelectrical parameters simultaneously, enabling classification of different cell types and quantification of multiple cell parameters for the first time.
Article
Chemistry, Analytical
Takayuki Kawai, Yasuhiro Mihara, Makiko Morita, Masahiko Ohkubo, Taiji Asami, Tomonobu M. Watanabe
Summary: Cyclic peptides (CPs) are considered next-generation drugs due to their cell-permeable potential and specific affinity, and single-cell cytoplasm mass spectrometry (SCC-MS) is a promising method for assessing their intracellular retention and transmembrane permeability.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Shengjie Chen, Shengsen Zhang, Rong Zhu
Summary: Fast and precise measurements of live single-cell biophysical properties are crucial for disease diagnosis and cytopathologic analysis. A computer vision method is proposed to track cell dielectrophoretic movements on a microchip, enabling efficient and accurate measurement of biophysical parameters and in situ extraction of cell texture features. The method achieves high measurement accuracy and efficiency, as well as high classification accuracies for various cell types.
ANALYTICAL CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Leland B. Hyman, Clare R. Christopher, Philip A. Romero
Summary: Experimental methods focusing on individual properties of single cells have highlighted the significance of cell-to-cell variability in biological processes. SNAPD, a technology for single-cell nucleic acid profiling in droplets, provides a rapid, high-throughput approach for analyzing transcriptional markers in cell populations, allowing for cell classification and quantification in heterogeneous samples.
NUCLEIC ACIDS RESEARCH
(2021)
Article
Nanoscience & Nanotechnology
Ting Deng, Xiaoyuan Shi, Wei Zhang, Zizhun Wang, Weitao Zheng
Summary: By introducing a template-growth strategy, the specific and areal capacitances of Metal Organic Frameworks (MOFs) as electrode materials for supercapacitors can be enhanced, leading to improved electrochemical performance.
Review
Genetics & Heredity
Siyuan Chen, Weibo Jiang, Yanhui Du, Manshi Yang, Yihan Pan, Huan Li, Mengying Cui
Summary: Single-cell sequencing technology is revolutionizing our understanding of cellular components, functions, and interactions by avoiding heterogeneity-related noise. It can characterize multiple cell types and uncover the mechanisms of gene regulatory networks, transcription dynamics, and proteomic profiling.
FRONTIERS IN GENETICS
(2023)
Article
Chemistry, Analytical
Shide Bakhtiari, Mohammad K. D. Manshadi, Mehmet Candas, Ali Beskok
Summary: The composition of the plasma membrane affects its biophysical properties, and changes in these properties can occur when new entities, such as drug molecules, are present. Assessing the effects of drugs on the biophysical properties of the cell membrane is crucial for understanding their specific and non-specific actions. This study discusses the potential application of a non-invasive technique for real-time characterization of cellular dielectric properties in assessing the biophysical properties of the cell membrane in response to interaction with different drugs.
Review
Biochemical Research Methods
Shimshon Belkin, Ji-Yen Cheng
Summary: Relying on living cells' biological responses and activity, bioluminescent whole-cell biosensors generate an optical signal in response to target compounds. The miniaturization of low-light detectors and their integration with microfluidics has enabled the development of portable devices for sensitive imaging and quantification of these signals. This review focuses on the integration of bioluminescence-based whole-cell biosensors with handheld optical detectors, particularly emphasizing the utilization of modern smartphones' low-light imaging capability. State-of-the-art miniaturization techniques applied to incorporating living cells into diverse hardware platforms and recording biologically generated photons are highlighted. The integration of sample introduction, host-cell activity maintenance, luminescence acquisition, data processing/presentation, and portability are also discussed.
CURRENT OPINION IN BIOTECHNOLOGY
(2023)
Review
Biotechnology & Applied Microbiology
Carmen Moccia, Kristina Haase
Summary: Breast cancer is the second leading cause of death among women worldwide. Different subtypes have different treatment strategies, and personalized treatments targeting components of the tumor microenvironment may help slow breast cancer progression, particularly for triple negative subtypes.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Review
Biotechnology & Applied Microbiology
Bixuan Li, Xi Ma, Jianghong Cheng, Tian Tian, Jiao Guo, Yang Wang, Long Pang
Summary: Cells are the building blocks of living organisms, and studying their growth, differentiation, apoptosis, and interactions can unravel the mysteries of life systems. However, cells exhibit considerable heterogeneity, even within the same cluster. Droplet microfluidics technology enables high-throughput, precise single-cell analysis by generating monodisperse droplets that serve as micro-laboratories. These droplets can be manipulated for single-cell screening and other studies. This review provides an overview of the design, generation, and control of droplet microfluidics, and its applications in single-cell culture, screening, detection, as well as tumor research.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Zengnan Wu, Ling Lin
Summary: Single-cell analysis is crucial for cell biology, drug discovery, and medical treatment. Conventional methods fail to analyze the real-time and continuous data of individual cells, while nanofluidics-based biochemical analysis offers advantages in sample processing and is widely used in single-cell capture, separation, and detection.
CHINESE CHEMICAL LETTERS
(2022)
Article
Biochemical Research Methods
Mei Jiang, Xiaojie Wang, Xiaoting Zhao, Yu Teng, Jian Chen, Junbo Wang, Wentao Yue
Summary: This study found that specific membrane capacitance and cytoplasmic conductivity can be used to classify tumor subtypes. By measuring the electrical properties of thousands of single tumor cells, significant differences were observed between cells with different phenotypes or genotypes.
Article
Engineering, Electrical & Electronic
Gilles Oudebrouckx, Daniel Nieder, Thijs Vandenryt, Seppe Bormans, Hildegard Mobius, Ronald Thoelen
Summary: The study introduces a novel method and prototype device for measuring the thermal conductivity of liquids under flow conditions, which demonstrates reliability and accuracy through proof-of-principle experiments.
SENSORS AND ACTUATORS A-PHYSICAL
(2021)
Article
Biochemistry & Molecular Biology
Hiroki Ide, Taiki Aoshi, Masato Saito, Wilfred Villariza Espulgar, Jonathan Campos Briones, Masahito Hosokawa, Hiroko Matsunaga, Koji Arikawa, Haruko Takeyama, Shohei Koyama, Hyota Takamatsu, Eiichi Tamiya
Summary: A new non-invasive screening method has been developed to determine the activation state of T-cells at the single-cell level. By examining the intracellular Ca2+ flux and motility of T-cells interacting with Antigen Presenting Cells, this method can efficiently identify activated T-cells with good specificity and stable proliferation, which is crucial for the development of adoptive immunotherapy.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
Ik Sung Cho, Prerak Gupta, Nima Mostafazadeh, Sing Wan Wong, Saiumamaheswari Saichellappa, Stephen Lenzini, Zhangli Peng, Jae-Won Shin
Summary: The researchers developed a microfluidic approach to create single cells in compartmentalized 3D hydrogel matrices with tunable ligand presentation. They found that cells elongate with asymmetric presentation of integrin adhesion ligands, while they expand isotropically with symmetric presentation. Furthermore, they discovered that asymmetric ligand presentation influences the lineage commitment of stem cells. This study demonstrates the potential of precisely controlling 3D ligand presentation to direct cell polarity in regenerative engineering and medicine.
Article
Engineering, Chemical
Jaylene Martinez, Masoud Aghajani, Yinan Lu, Adrienne K. Blevins, Shouhong Fan, Mengyuan Wang, Jason P. Killgore, Stefano Berti Perez, Jaivin Patel, Christina Carbrello, Sean Foley, Ryan Sylvia, Rong Long, Robert Castro, Yifu Ding
Summary: This study investigated the kinetics of capillary infiltration of viscous polypropylene in polyethersulfone membranes with different hydrophilicities, finding that infiltration dynamics are influenced by various factors. The mechanical integrity of the bonded films decreases slightly with increasing infiltration depth, as quantified by a modified T-peel test.
JOURNAL OF MEMBRANE SCIENCE
(2022)
Article
Public, Environmental & Occupational Health
Wentao Yue, Enjie Zhang, Ruixia Liu, Yue Zhang, Chengrong Wang, Shen Gao, Shaofei Su, Xiao Gao, Qingqing Wu, Xiaokui Yang, Aris T. Papageorghiou, Chenghong Yin
Summary: The China Birth Cohort Study is a national study aiming to investigate risk factors for birth defects and develop strategies for their reduction. The study has completed two phases of recruitment and has collected biological samples from participants. The study aims to recruit 500,000 participants by December 2021.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Engineering, Mechanical
Mahyar Afshar-Mohajer, Xingwei Yang, Rong Long, Min Zou
Summary: This study investigates the friction and deformation behavior of micro/nano-hierarchical textures, revealing a coupling between micropillar deformation and nanohair height. Furthermore, it is found that the bending of long nanohairs can provide assistive sliding forces, and lateral force can develop even before sliding due to the buckling of longer nanohairs.
TRIBOLOGY INTERNATIONAL
(2022)
Article
Cell Biology
Hongyu Zhao, Yan Gao, Jinwei Miao, Suwen Chen, Jie Li, Zhefeng Li, Chenghong Yin, Wentao Yue
Summary: The study explored the heterogeneity of ovarian cancer through single-cell RNA-seq and identified a subtype associated with poor survival and clinical response. Utilizing specific gene profiles, four phenotypes with different survival and response to immunotherapy were identified, advancing the understanding of OC pathogenesis and leading to promising therapeutic strategies.
CELL DEATH & DISEASE
(2021)
Article
Engineering, Mechanical
Yinan Lu, Yuan Qi, Michely Tenardi, Rong Long
Summary: This experimental study investigates mixed-mode crack propagation in thin sheet specimens of a soft silicone elastomer. The crack propagation trajectories and energy release rate were influenced by the inclined angle, showing that fracture toughness was approximately mode independent. The tangent direction of the crack trajectory was perpendicular to the direction of maximum principal stretch in the reference configuration.
EXTREME MECHANICS LETTERS
(2021)
Article
Engineering, Mechanical
Chenghai Li, Zhijian Wang, Yang Wang, Qiguang He, Rong Long, Shengqiang Cai
Summary: The polymer network structures and topologies in hydrogels play a significant role in determining their mechanical properties. Research shows that the initial monomer concentration during synthesis can influence the elasticity, stretchability, and fracture properties of hydrogels. These findings provide important insights for synthesizing hydrogels with tailorable mechanical properties.
EXTREME MECHANICS LETTERS
(2021)
Article
Materials Science, Multidisciplinary
Luxia Yu, Zepeng Lei, Xiaohao Sun, Peiran Ding, Aaron Wesche, Yinghua Jin, Wei Zhang, Rong Long
Summary: Polyimine is a covalent adaptable network with dynamic imine bonds, suitable for recycling, reprocessing, and repair. Through a powder-based compression molding method, carbon fiber-reinforced polyimine composites can be rapidly fabricated with mechanical properties similar to those produced through traditional methods. Additionally, in situ, mold-free repair of polyimine composites at low temperature and pressure was demonstrated, showcasing the malleability, weldability, and full recyclability of the material.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
XiaoHao Sun, Ke Wang, HengAn Wu, Jian Chen, Rong Long
Summary: The finite element method is widely used to simulate the process of cells entering narrow channels. This study focuses on the effects of frictional boundary conditions in these simulations. By continuously updating the boundary conditions according to the contact status, the researchers study how pressure boundary conditions and friction coefficient affect the simulated cell entry process. The results show that different pressure boundary conditions produce the same result under frictionless contact but considerably different results under frictional contact. Furthermore, a larger friction coefficient can significantly reduce the entry length under a prescribed pressure or a certain entry time.
MECHANICS OF MATERIALS
(2022)
Article
Engineering, Chemical
Brodie K. Hoyer, Rong Long, Mark E. Rentschler
Summary: Rolling contact experimentation is a useful method for studying adhesive contact between surfaces. The researchers have designed a tribometric device to capture forces between a rolling indenter and substrate, and validated its effectiveness through experiments. This device can facilitate investigations of rolling contact mechanics in medical robotics.
Article
Engineering, Mechanical
Karl Johannes, Kristin Calahan, Leah Bowen, Emily Zuetell, Rong Long, Mark Rentschler
Summary: This study investigates the adhesion modulation of an elastomeric micro-patterned surface with both rigid and soft materials by applying equibiaxial tensile strain. Experimental results show that the applied strain substantially influences the adhesion behavior of the surface with both types of probes, with a different underlying mechanism for each.
EXTREME MECHANICS LETTERS
(2022)
Article
Multidisciplinary Sciences
Kristin N. Calahan, Yuan Qi, Karl G. Johannes, Mark E. Rentschler, Rong Long
Summary: The study found that micropatterned surfaces can generate enhanced shear traction on soft tissue-like materials, thereby improving the anchoring performance of medical devices on tissue. By experimentally measuring microscale three-dimensional deformation, it was revealed that lateral contact between pillar arrays and soft hydrogel substrates plays a key role in shear response.
Article
Engineering, Mechanical
Qiang Guo, Julien Caillard, Davide Colombo, Rong Long
Summary: In this study, a scaling theory is developed to understand the dynamic effect of crack growth in viscoelastic solids under cyclic loading. The coupling between cyclic loading, crack growth, and viscoelastic creep is found to govern the viscoelastic dissipation. A simple integral equation is derived to predict the crack growth velocity under different cyclic loading frequencies.
EXTREME MECHANICS LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Zepeng Lei, Hongxuan Chen, Chaoqian Luo, Yicheng Rong, Yiming Hu, Yinghua Jin, Rong Long, Kai Yu, Wei Zhang
Summary: Chemical recycling of polymers is crucial for improving the circular economy and sustainability of plastics. This study demonstrates the possibility of recycling traditional polycyanurate thermosets by activating dormant covalent bonds. By redirecting the synthetic route and creating a reversible synthetic pathway, previously inaccessible alkyl-polycyanurate thermosets with high recyclability and reprocessing capability were successfully synthesized.
Article
Polymer Science
Jaylene Martinez, Shouhong Fan, Salil Rabade, Adrienne K. Blevins, Kieran Fung, Jason P. Killgore, Stefano Berti Perez, Kathy Youngbear, Christina Carbrello, Sean Foley, Xiaoyun Ding, Rong Long, Robert Castro, Yifu Ding
Summary: This study systematically examines the capillary infiltration of polypropylene within polyethersulfone membranes and identifies the significant influence of asymmetric pore structure on the infiltration kinetics. The Cai model successfully captures the accelerated infiltration rate over time. Chemical modification only affects the initial infiltration rate and has no significant impact on the later stage. Mechanical integrity tests reveal complex debonding behaviors, with the peel force corresponding to membrane failure being larger. The presence of PP nanofibers pulled out during debonding highlights the weak mechanical interlocking due to low surface porosity.
Article
Medicine, Research & Experimental
Jiahao Guo, Xiaoyang Han, Jie Li, Zhefeng Li, Junjie Yi, Yan Gao, Xiaoting Zhao, Wentao Yue
Summary: By integrating single-cell sequencing data, researchers discovered a cell subcluster closely associated with metastasis in ovarian cancer and identified RAB13 as its key marker. Experimental results showed that downregulation of RAB13 expression can reduce migration and invasion of ovarian cancer cells, and several potential drugs that may inhibit RAB13 were predicted. This study provides new insights and potential therapeutic targets for the research on ovarian cancer metastasis.
JOURNAL OF TRANSLATIONAL MEDICINE
(2023)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
