Article
Biochemical Research Methods
Majid Arvand, Hoda Ilkhani, Mohamad Reza Ganjali, Akram Pourhabib
Summary: A new Tb complex Tb(QS)3 was used to investigate the interaction between the complex and double-stranded DNA, leading to the design of a new DNA biosensor. The interaction mechanism, primarily intercalative interaction, was elucidated using electrochemical methods such as cyclic voltammetry and differential pulse voltammetry.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Chemistry, Analytical
Yao Chen, Yu Zhong, Ji-Xing Ye, Yun Lei, Ai-Lin Liu
Summary: In this study, a sensitive and selective electrochemical DNA biosensor was developed for the determination of a osteosarcoma-related survivin gene. The proposed strategy used a simple and low-cost working electrode, with no need for other substances for electrode or DNA functionalization. The mode of interaction between celestine blue (CB) and DNA was studied, and it was found that the possible mode was intercalation with a binding number of 2 and a binding constant beta of 10(12.87). The label-free electrochemical DNA biosensor showed a good linear relationship towards the target gene and had a low detection limit of 0.046 nM.
Article
Chemistry, Analytical
Rokhsareh Abedi, Jahan Bakhsh Raoof, Ayemeh Bagheri Hashkavayi, Maryam Asghary
Summary: The label-free electrochemical DNA hybridization biosensor developed based on gold nanocubes modified graphite screen-printed electrodes is able to effectively detect the interaction between epirubicin and short sequence DNA of prostate cancer gene, with a linear detection range from 0.04 to 20.0 mu M and a detection limit of 0.01 mu M. The biosensor exhibits good selectivity and demonstrated applicability in human serum samples, serving as a reproducible and stable device for EPI determination.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Esmaeel Alipour, Sheida Norouzi, Shokoufeh Moradi
Summary: An electrochemical DNA biosensor using quercetin as an electroactive indicator was developed for specific target DNA detection, achieving a detection limit of 83 pM with a relative standard deviation of 4.6%. The biosensor was successfully applied for the detection of short sequences of hepatitis C virus and showed selective response to the target DNA.
ANALYTICAL METHODS
(2021)
Article
Nanoscience & Nanotechnology
Niamat Khuda, Subramaniam Somasundaram, Ajay B. Urgunde, Christopher J. Easley
Summary: A variety of EC biosensors are critical in disease diagnostics, with DNA-based EC sensors showing promise in detecting different analyte classes. This study used methylene blue-labeled DNA strands to monitor the kinetics of DNA hybridization at the electrode surface. By varying the position of the DNA segment relative to the electrode surface and the ionic strength of the solution, interference with DNA hybridization was observed closer to the surface, with greater interference at lower ionic strength. This work highlights the importance of salt concentration and DNA hybridization site in designing DNA-based EC sensors that directly measure hybridization at the electrode surface.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Ying Liu, Lingqi Kong, Zeshuai Han, Ruo Yuan, Yaqin Chai
Summary: A novel 3D DNA nanostructure with high loading capacity of methylene blue (MB) was used to fabricate an electrochemical biosensor for ultrasensitive detection of Pb2+. The DNA nanostructure was constructed through hybridization chain reaction (HCR) triggered by mimic targets generated from Pb2+-dependent DNAzyme cleavage cycling. The 3D DNA nanostructure showed excellent carrying capacity of MB and generated a remarkable electrochemical signal. The proposed strategy provides a promising approach for ultrasensitive detection of biomarkers in diseases diagnosis and environmental monitoring.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Huahui Gao, Jianglong Yao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: This study developed a sensitive electrochemical aptamer sensor for the detection of ochratoxin A (OTA), one of the most toxic mycotoxins in food. The sensor showed high sensitivity, selectivity, and potential for monitoring OTA in real samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Zhen Song, Rong Li, Xiqin Yang, Zhanhua Zhang, Xiliang Luo
Summary: This study developed an electrochemical biosensing platform with enhanced antifouling abilities by immobilizing DNA-peptide conjugates onto an electrode. The biosensor exhibited enhanced antifouling properties and was capable of detecting low fouling proteins directly in complex biological samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Analytical
Fengzhen Li, Delun Chen, Wang He, Juan Peng, Yang Cao, Jinchun Tu, Xiaohong Wang
Summary: An electrochemical biosensor based on competitive single-stranded DNA modification was established to detect Scrub typhus, with a wide linear detection range achieved by combining nano-flower NiFe layered double hydroxide (NiFe-LDH) with gold nanoparticles. The competitive relationship between beacon DNA (B-DNA) and Scrub typhus DNA (T-DNA) reduced experimental procedures and response time, enabling fast electrochemical detection of DNA, providing a promising avenue for disease diagnosis.
Article
Chemistry, Analytical
Dongmei Wang, Huan Zhou, Fei Liu, Yongxin Li
Summary: This paper presents a robust and highly integrated DNA bipedal walker based electrochemical biosensor for ultrasensitive miRNA-21 detection. Using click chemistry, enzyme-free target recycling amplification strategy and programmed catalysis hairpin assembly, the biosensor demonstrated high analysis performance with wide detection range, low detection limit, and high selectivity. The nanosensor, with proximity-dependent hybridization and programmed catalysis hairpin assembly, offers a promising approach for miRNA biomarker expression in cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Riham Zayani, Amal Rabti, Sami Ben Aoun, Noureddine Raouafi
Summary: The study introduces a novel method for sensitive detection of miRNAs levels using a dual signal readout system involving competitive hybridization of miR-21 target and its biotinylated analog. The bioplatform demonstrates low detection limits, wide linear calibration range, excellent selectivity towards non-complementary miRs, and acceptable distinction with single nucleotide mismatched sequences. Furthermore, the method was successfully used to determine miR-21 expression levels in blood sera from breast cancer patients.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Shan-Shan Shi, Li-Ping Jia, Wei Zhang, Rong-Na Ma, Lei Shang, Xiao-Jian Li, Huai-Qing Zhao, Huai-Sheng Wang
Summary: A label-free electrochemical aptasensor with Bi-Sb alloy materials (Bi-Sb AMs) was developed for ultrasensitive detection of HER-2, a prognostic biomarker for breast cancer. The aptasensor performance was greatly enhanced by the introduction of high conductivity Bi-Sb AMs. Integration of the aptasensor with the Sensit Smart U-disk electrochemical analyzer enabled point-of-care testing (POCT) for HER-2, with a wide linear response range and low detection limit.
Article
Biophysics
Feng Qiu, Xiaoyan Gan, Jianglong Yao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a sensitive detection method for nuclear factor-kappa B p50 (NF-KB p50) was proposed by integrating hybridization chain reaction (HCR)-activated Cas12a enzyme with bio-responsive DNA hydrogels. The method achieved highly enhanced electrochemical signals for detecting target molecules at a low detection limit and successfully detected NF-KB p50 in lysate of HeLa cells.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
HuanWen Han, Kazuyuki Nobusawa, Ichiro Yamashita
Summary: The DNA intercalator [Ru(bpy)(2)DPPZ](2+) was found to significantly increase charge transfer in electrochemical impedance spectroscopy (EIS), making it a promising candidate for applications in dsDNA detection or PCR monitoring. Future developments may lead to EIS sensors that do not require specific electrode modifications.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Skomantas Serapinas, Justina Gineityte, Marius Butkevicius, Rapolas Danilevicius, Marius Dagys, Dalius Ratautas
Summary: This paper presents a new bioelectronic device for the detection of nuclease activity in various fluids. The developed sensor enables rapid and sensitive determination of DNase activity, with high accuracy and reproducibility demonstrated in real human saliva samples. The technology has the potential to improve nuclease quality control processes in the pharmaceutical/biotechnology industry and provide new insights into the importance of nucleases for medical applications.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Feng Gao, Yaru Chu, Yijing Ai, Weiqiang Yang, Zhenyu Lin, Qingxiang Wang
Summary: A label-free and sensitive electrochemical biosensing strategy has been proposed for detecting the hepatocellular carcinoma biomarker miRNA-122 based on the ion-barrier effect. The hybridization reaction induced ion-barrier effect enables the monitoring of miRNA-122, with the capability to analyze it within a certain concentration range.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Analytical
Weiqiang Yang, Guiyun Zhang, Jiancong Ni, Qingxiang Wang, Zhenyu Lin
Summary: A magnetic graphene oxide (M-GO) assisted homogeneous electrochemiluminescence (ECL) aptasensor was developed for the highly sensitive detection of okadaic acid (OA). The composite ECL probe achieved high sensitivity by adsorbing aptamer and Ru(bpy)(3)(2+) in M-GO, allowing proportional release of Ru(bpy)(3)(2+) to generate the ECL signal upon dissociation of OA aptamer.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Qinghua Wang, Tiantian Liu, Yingyu Chen, Qingxiang Wang
Summary: The study describes the synthesis of a nanocomposite with heterostructure of metallic nickel and nickel sulfide, which exhibits excellent energy storage capabilities in both supercapacitors and zinc ion batteries.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Xinyi Liang, Xu Du, Ao Liu, Zhixiong Cai, Jingwen Li, Maosheng Zhang, Qingxiang Wang, Jingbin Zeng
Summary: This study proposes a plasmonic nanosenosr for the detection of mercury(II) in natural samples. The sensor shows high selectivity and feasibility, making it suitable for analyzing complex matrices directly.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Physical
Yun Ling, Ya-ru Chu, Feng Gao, Qing-yun Feng, Hui-qi Xie, Yong Shao, Qing-xiang Wang
Summary: Metal-organic frameworks (MOFs) have promising applications in electrochemical sensing, and this study developed a novel label-free electrochemical sensing strategy for detecting cardiac troponin I (cTnI) using Cu-MOF-74. The electrochemical assay demonstrated that the immunoaffinity reaction between cTnI and anticTnI effectively inhibited the electrochemical signal of Cu-MOF-74, indicating the potential of Cu-MOF-74-based interface in label-free cTnI analysis.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Biophysics
Feng Gao, Fengping Zhan, Songling Li, Philip Antwi-Mensah, Li Niu, Qingxiang Wang
Summary: Dual signal interface was achieved by in-situ grafting signal tags on Pb2+-binding aptamer and Hg2+-binding aptamer immobilized on gold electrode, enabling simultaneous detection of Pb2+ and Hg2+. The sensor showed low detection limits and was successfully applied for determination of Pb2+ and Hg2+ in real water samples.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Analytical
Zhiping Song, Juan Song, Feng Gao, Xiaoping Chen, Qinghua Wang, Yanan Zhao, Xuguang Huang, Chaoyong Yang, Qingxiang Wang
Summary: In this study, a novel electrochemical aptasensor was developed for the rapid and accurate determination of cardiac troponin I. The sensor exhibited ultra-low detection limit and a wide linear range.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Environmental
Manli Wang, Xuan Zheng, Yi Li, Zehua Zou, Yun Ling, Qingxiang Wang
Summary: Developing bifunctional electrocatalysts with abundant reserves and efficient performance is crucial for alkaline water electrolysis. In this study, antiperovskite nitride (FexCu1-x)4N particles anchored on Cu2O nanosheets were synthesized via one-step solution combustion synthesis using KCl. The assembly of (FexCu1-x)4N and Cu2O promotes charge transfer and increases reaction kinetics and active sites. The optimized (Fe1xCux)4N-Cu2O heterostructure exhibits superior bifunctional performance for water electrolysis compared to precious metal couples.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Electrochemistry
Qinghua Wang, Limei Zheng, Yun Ling, Philip Antwi-Mensah, Qingxiang Wang
Summary: The facile and low-cost technology for the fabrication of high-performance electrode material for supercapacitors is crucial for green energy storage. By utilizing thermal treatment and potentiostatic oxidation, the capacitance of commercial carbon cloth is significantly increased, resulting in a high-performance self-standing cathode. This research has a significant impact on energy storage technology.
ELECTROCHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Zehao Wang, Ningning Gao, Zhenmao Chen, Feng Gao, Qingxiang Wang
Summary: An electroactive metal-organic coordination polymer was prepared for immobilizing the bioprobe and constructing label-free biosensors. The biosensor was characterized using AFM, ATR-FTIR, and electrochemical methods. The aptasensor showed high sensitivity and selectivity for thrombin detection in complex samples.
Article
Nanoscience & Nanotechnology
Zhenmao Chen, Yijing Ai, Weiqiang Yang, Li Niu, Qingxiang Wang, Feng Gao
Summary: A novel immobilization-and label-free electrochemical strategy has been developed for the detection of miRNA let-7a using magnetic Fe3O4@hydroxyapatite (Fe3O4@HAP) and the specific adsorption of a duplex structure. With the introduction of the label-free signal molecule Nile blue (NB) and its intercalation into the pDNA-miRNA duplex, a strong sensing signal is achieved without the need for nuclease-assisted cyclic amplification. The sensing system shows a wide linear range (1.0 fM to 100 nM) and a low detection limit (0.051 fM) for miRNA let-7a analysis, and exhibits high specificity.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Zehao Wang, Yangyi Wu, Philip Antwi-Mensah, Zhenmao Chen, Weiqiang Yang, Li Niu, Feng Gao, Qingxiang Wang
Summary: The construction of an anti-fouling biosensing interface with inherent electroactivity is advantageous for improving the practicality of electrochemical biosensors. In this study, an electroactive biosensing interface with excellent biofouling resistance ability was developed using a hybrid membrane of Ce3+-poly(dopamine) (PDA) and Prussian blue (PB). The hybrid film not only enhances the hydrophilicity and biofouling resistance ability of the interface, but also acts as the immobilization matrix for the detection of miRNA Let-7a. The biosensor was capable of detecting miRNA Let-7a in human serum samples within a wide concentration range.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Yun Ling, Qingyun Feng, Huiqi Xie, Xuan Zheng, Xiaoping Chen, Zehua Zou, Aifen Liu, Jing Tang, Yi Li, Qingxiang Wang
Summary: A phase-transition engineering strategy is developed to regulate oxygen vacancy and metal doping on the surface of M-TiO2, promoting both the selectivity and activity of the nitrogen reduction reaction (NRR). The strategy features simple synthesis process, high phase-transition efficiency, cost-effective materials, and scalability. Experimental results and density functional theory calculations show that surface oxygen vacancies and doping Fe atoms play crucial roles in the NRR, resulting in high NH3 yield and Faradaic efficiency.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Analytical
Fengping Zhan, Yanan Zhao, Xiaohui Dai, Jingbin Zeng, Qingxiang Wang
Summary: The development of a new method for rapid screening of antibiotics residues in food is important for food safety. A nanocomposite of polyaniline@copper-1,3,5-benzenetricarboxylic acid was directly prepared on an electrode surface, and a tetracycline aptamer was assembled onto the electrode to create an electrochemical aptasensor for tetracycline detection. The aptasensor showed high sensitivity and a wide detection range.
MICROCHEMICAL JOURNAL
(2024)
Article
Chemistry, Applied
Chenxin Chen, Suqi He, Kamran Dastafkan, Zehua Zou, Qingxiang Wang, Chuan Zhao
Summary: Sea urchin-like NiMoO4 nanorod arrays demonstrate efficient catalytic activity and stability for urea oxidation and hydrogen evolution. The difference in electrocatalytic activity and selectivity is attributed to the variation in lattice oxygen content. This material shows great potential for energy conversion.
CHINESE JOURNAL OF CATALYSIS
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
