Article
Biochemical Research Methods
Wenhan Zhao, Xiaopeng Shang, Boran Zhang, Dan Yuan, Binh Thi Thanh Nguyen, Wenshuai Wu, Jing Bo Zhang, Niancai Peng, Ai Qun Liu, Fei Duan, Lip Ket Chin
Summary: This study systematically investigates the flow transition process in the hydrodynamic focusing mechanism, revealing the transition from the squeezed focusing state to the over-squeezed anti-focusing state. The recovery rate of cell analysis can be maintained by limiting the Reynolds number below 30. These findings provide new insights into microfluidic cytometric analyses with various applications in food safety, water monitoring, and healthcare sectors.
Article
Engineering, Electrical & Electronic
Yogesh M. Patel, Ritika Malik, Kedar Khare, Supreet Singh Bahga
Summary: We propose a microfluidic holographic cytometry technique that uses three-dimensional hydrodynamic focusing to accurately visualize, classify, and quantify cells and particles in a mixture. This technique achieves high-resolution holographic imaging without the need for computationally-expensive numerical refocusing used in existing methods. It also prevents cell clustering and can be fabricated at a low cost. The technique shows promise for label-free classification and quantification of infected cells in various applications.
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
(2023)
Review
Chemistry, Analytical
Sheng Yan, Dan Yuan
Summary: The development of microfluidic technologies, particularly microflow cytometry with 3D focusing capabilities, has shown great promise in single-cell analysis, offering a wide range of applications in biology and medicine.
Article
Pharmacology & Pharmacy
Roni Sverdlov Arzi, Asaf Kay, Yulia Raychman, Alejandro Sosnik
Summary: Nanoprecipitation and microfluidics technology are effective methods for producing pure drug nanoparticles and optimizing product performance. The use of specific microfluidic devices can lead to the production of rounded, optimized nanoparticles.
Article
Nanoscience & Nanotechnology
Xiaofei Yuan, Andrew Glidle, Hitoshi Furusho, Huabing Yin
Summary: Traditional two-dimensional fluid control strategies in microfluidic cell sorting have limitations in terms of precision and purity, while devices based on three-dimensional hydrodynamics offer better flow-focusing characteristics but are restricted by arbitrary sample positioning. The 3D hydrodynamic focusing sorting platform designed in this study has advantages in precisely controlling sample velocity and position, showing potential for high-accuracy Raman activated sorting.
MICROFLUIDICS AND NANOFLUIDICS
(2021)
Article
Mechanics
M. Lopez, M. G. Cabezas, J. M. Montanero, M. A. Herrada
Summary: In this study, the stability of hydrodynamic focusing to produce microemulsions is investigated experimentally and numerically. It is found that the distance between the feeding capillary and the focusing orifice affects the liquid ejection stability. Confined selective withdrawal enhances the stability of the microdripping mode. Surfactants stabilize the meniscus and promote the transition from microdripping to jetting. The global stability analysis accurately predicts the critical flow rate ratio and the droplet emission frequency.
JOURNAL OF FLUID MECHANICS
(2022)
Article
Chemistry, Analytical
Chengxin Wu, Xing Wei, Xue Men, Yulong Xu, Junjie Bai, Yu Wang, Lei Zhou, Yong-Liang Yu, Zhang-Run Xu, Ming-Li Chen, Jian-Hua Wang
Summary: We constructed an open and low-cost flow cytometer that integrates single cell aligning and fluorescence detection functions. The hardware cost for the LIF detection unit and 3D focusing device is $3200 and $400 respectively. The flow cytometer showed favorable assay precision and accuracy, and was successfully applied for evaluating ROS generation in single HepG2 cells.
Article
Chemistry, Analytical
Dayananda Desagani, Shani Kleiman, Teddy Zagardan, Hadar Ben-Yoav
Summary: Three-dimensional-printed lab-on-a-chip (LOC) devices offer cost-efficient and easy-to-handle solutions for particle analysis, allowing for remote diagnosis and monitoring of medical conditions such as inflammation.
Review
Chemistry, Analytical
Zhao Zhang, Xiaowen Huang, Ke Liu, Tiancong Lan, Zixin Wang, Zhen Zhu
Summary: Cellular heterogeneity is important in cell-based assays, and electrical impedance sensing technology allows for rapid, non-invasive acquisition of single cell electrical parameters. These parameters are closely related to cellular properties and activities, and devices such as impedance flow cytometry and electrical impedance spectroscopy are used for cell recognition, counting, viability detection, phenotypic assay, and other cell detection. Impedance sensing technology shows promise in single-cell analysis.
Article
Chemistry, Analytical
Anita Banyai, Eszter Leelossyne Toth, Mate Varga, Peter Furjes
Summary: This study investigates the inertial focusing phenomenon and its application in sample preparation and target manipulation in particulate suspensions. The asymmetric channel geometry is designed to promote sheathless focusing or size-dependent sorting. Experimental results are compared to simulation models to characterize the focusing behavior of particles with sizes close to blood cells and bacteria.
Article
Mechanics
Giridar Vishwanathan, Gabriel Juarez
Summary: Oscillatory flows have the potential to overcome limitations of using steady flows for inertial focusing due to low particle Reynolds numbers. Unsteady inertial forces on inertial focusing have not been thoroughly examined. Experimental and theoretical studies show that oscillatory flows are remarkably efficient for inertial focusing, even at low particle Reynolds numbers.
JOURNAL OF FLUID MECHANICS
(2021)
Article
Environmental Sciences
Carlos A. S. Araujo, Claude Belzile, Jean-Eric Tremblay, Simon Belanger
Summary: This study investigated the seasonal and spatial variability of surface phytoplankton assemblages and associated environmental niches in a human-impacted subarctic coastal bay in Quebec, Canada. The results showed that the phytoplankton assemblages in the Bay of Sept-iles were more diverse than in the central portion of the St. Lawrence Estuary. The temporal distribution of the phytoplankton assemblages reflected the major seasonal signal of the nearshore subarctic environment.
FRONTIERS IN MARINE SCIENCE
(2022)
Article
Chemistry, Analytical
Diwakar M. Awate, Cicero C. Pola, Erica Shumaker, Carmen L. Gomes, Jaime J. Juarez
Summary: Despite the limitations of flow cytometers, a 3D-printed imaging platform (3DPIP) has been developed to accurately count particles and conduct fluorescence microscopy efficiently. The 3DPIP utilizes a custom particle counter code and machine vision-based algorithm to identify and count particles, showing comparable accuracy to commercial particle counters. Additionally, the platform can perform static experiments and flow-through experiments effectively, making it a promising tool for use in resource-limited clinical environments.
Article
Optics
Daniele Pirone, Massimiliano Maria Villone, Pasquale Memmolo, Zhe Wang, Volodymyr Tkachenko, Wen Xiao, Leiping Che, Lu Xin, Xiaoping Li, Feng Pan, Pietro Ferraro, Pier Luca Maffettone
Summary: In the application of digital holography (DH) for lab on chip, cells passing through the microscope's field of view can be detected and analyzed even if they are flowing at different depths. This is achieved by retrieving in-focus imaging of each cell through DH. The preferred configuration for DH in flow-cytometry mode involves the rotation of cells along the microfluidic channel, allowing for the retrieval of 3D refractive index maps of flowing cells. Hydrodynamic interactions were investigated and found to have a quantitative effect on cell rotation but not on cell deformation, with the effect being negligible in terms of tomogram recovery.
OPTICS AND LASERS IN ENGINEERING
(2022)
Article
Mechanics
Xinyu Mao, Irmgard Bischofberger, A. E. Hosoi
Summary: The influence of surface roughness on transition to turbulence in a Mach 4.5 boundary layer is investigated. It is found that the shape and location of the localized roughness have a significant impact on the amplification of instability waves. A protruding roughness acts destabilizing upstream of the synchronization point and stabilizing downstream.
JOURNAL OF FLUID MECHANICS
(2023)
Article
Nanoscience & Nanotechnology
Alex H. Wrede, Jie Luo, Reza Montazami, Anumantha Kanthasamy, Nicole N. Hashemi
Summary: Reactive astrocytes play a vital role in the brain's response to traumatic brain injuries. Cavitation in the skull during TBI can have detrimental effects, with upregulated harmful genes linked to neurodegenerative diseases. Studying the genetic expression of astrocytes in response to cavitation can help optimize treatment methods and understand the potential implications of cranial cavitation in TBI.
Review
Chemistry, Analytical
Gabriel A. Clarke, Brenna X. Hartse, Amir Ehsan Niaraki Asli, Mehrnoosh Taghavimehr, Niloofar Hashemi, Mehran Abbasi Shirsavar, Reza Montazami, Nima Alimoradi, Vahid Nasirian, Lionel J. Ouedraogo, Nicole N. Hashemi
Summary: Organ-on-chip devices have brought hope to pharmaceutical and tissue engineering fields, but their limitations in real-time monitoring and sensing capabilities have been realized. By integrating sensors into these devices, the gap in understanding between lab research and the natural world can be bridged.
Review
Green & Sustainable Science & Technology
Reihaneh Jamshidi, Mehrnoosh Taghavimehr, Yuanfen Chen, Nicole Hashemi, Reza Montazami
Summary: Transient technology plays an important role in sustainable system design and implementation, widely used in medical implants, environmental sensors, and hardware-secured devices; Controlled disintegration of systems without harsh solvents is a step towards achieving green and sustainable electronics.
ADVANCED SUSTAINABLE SYSTEMS
(2022)
Article
Engineering, Biomedical
Saurabh S. Aykar, Nima Alimoradi, Mehrnoosh Taghavimehr, Reza Montazami, Nicole N. Hashemi
Summary: This study presents a microfluidic-based method for cell seeding inside alginate hollow microfibers, where mouse astrocytes are passively seeded. The addition of collagen I and poly-d-lysine enhances cell attachment and viability compared to nonadditive-based hollow microfibers.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Biophysics
Mehran Abbasi Shirsavar, Mehrnoosh Taghavimehr, Lionel J. Ouedraogo, Mojan Javaheripi, Nicole N. Hashemi, Farinaz Koushanfar, Reza Montazami
Summary: This study investigates the impact of key parameters on the conductivity of E-jet printed circuits and develops a machine learning model using collected experimental data to predict the characteristics of the printed circuits. Results show that the K-NN model and random forest are the best methods for classifying electrode conductivity.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Engineering, Manufacturing
Vahid Nasirian, Amir Ehsan Niaraki-Asli, Saurabh S. Aykar, Mehrnoosh Taghavimehr, Reza Montazami, Nicole N. Hashemi
Summary: Carbon-modified fibrous structures with high biocompatibility have attracted attention for their low cost, sustainability, abundance, and excellent electrical properties. This study introduces a microfluidic-based technique to produce alginate hollow microfibers incorporated with water dispersed modified graphene. The addition of graphene enhances the conductivity without changing the inner dimension of the hollow region. The improved electrochemical performance makes these microfibers suitable for developing flexible capacitors for smart health electronics.
3D PRINTING AND ADDITIVE MANUFACTURING
(2022)
Article
Biophysics
Amir Niaraki, Mehran Abbasi Shirsavar, Saurabh S. Aykar, Mehrnoosh Taghavimehr, Reza Montazami, Nicole N. Hashemi
Summary: Real-time and high-throughput monitoring of neural cells exposed to injury mechanisms using microelectrode arrays and electrical impedance spectroscopy is demonstrated in this study. Aqueous graphene is used for microelectrode fabrication, and the surface morphology and electrical properties of the electrodes are characterized. The attachment and impedance changes of the neural population on the graphene microelectrodes are quantified, and the impact of UV exposure on neural detachment is monitored.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biochemical Research Methods
Tannaz Tavari, Saber Meamardoost, Naserodin Sepehry, Pooria Akbarzadeh, Mostafa Nazari, Nicole N. Hashemi, Mohsen Nazari
Summary: A comprehensive systematic optimization framework for accurately predicting an efficient electrode geometry is currently unavailable. In this study, different geometries, including 3D step electrodes, were designed to fabricate AC electroosmosis micro-pumps. Optimization of both geometrical and nongeometrical parameters was essential for achieving optimal performance. Numerical simulation and fabrication of a microchip validated the effectiveness of the proposed geometry in outperforming state-of-the-art micro-pumps in terms of fluid velocity, electrode density, and channel length.
Article
Education & Educational Research
Christopher T. Boyle, Nicole N. Hashemi
Summary: This study investigated the impact of an early learning assessment on students' motivation to improve their performance. It analyzed the effect of a first exam, with an average below a passing grade, on students' outcomes in a mechanical engineering course. The results showed that after the inadequate performance on the first exam, students were motivated to achieve higher grades in subsequent exams and assessments.
EDUCATION SCIENCES
(2023)
Article
Engineering, Multidisciplinary
Rajeendra L. Pemathilaka, Nicole N. Hashemi
Summary: In an effort to achieve sustainable drug discovery, a proof-of-concept study was conducted to examine the effects of pharmaceutical agents on neural cells transported across the placental barrier. The concerns regarding the potential impact of these agents on fetus necessitate further investigation. A placenta-on-a-chip model was utilized to study the transport of naltrexone (NTX) and its primary metabolite 6 beta-naltrexol. Neural cells exposed to the transported NTX/6 beta-naltrexol exhibited altered gene expression and reduced cell viability, indicating the significance of this study in understanding the consequences of pharmaceutical agent exposure on developing fetuses and premature brains.
INNOVATION AND EMERGING TECHNOLOGIES
(2023)
Article
Materials Science, Biomaterials
Lionel J. Ouedraogo, Mychal J. Trznadel, Mckayla Kling, Vahid Nasirian, Alexandra G. Borst, Mehran Abbasi Shirsavar, Andrew Makowski, Marilyn C. Mcnamara, Reza Montazami, Nicole N. Hashemi
Summary: The manufacturing of 3D cell scaffoldings provides advantages for modeling diseases and injuries. A triple-flow microfluidic device is developed to fabricate alginate/graphene hollow microfibers. These unique 3D hollow scaffolds can enhance the available surface area for nutrient transport and have higher electrical conductivity.
Article
Nanoscience & Nanotechnology
Rajeendra L. Pemathilaka, Nima Alimoradi, David E. Reynolds, Nicole N. Hashemi
Summary: In this study, a placental microsystem was developed to investigate the transport and effects of pharmaceutical agents on the developing fetus. The microsystem successfully replicated the structural and physiological characteristics of the placental barrier. It was found that fluid shear stress played a role in the formation of elongated microvilli. The concentration of pharmaceutical agents in the fetal channel differed from that in the maternal channel, indicating the presence of the placental barrier. Additionally, the study reported gene expression changes in epithelial and endothelial cells after exposure to pharmaceutical agents.
ACS APPLIED BIO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Nicole N. Hashemi, Rajeendra L. Pemathilaka, Nima Alimoradi, David E. Reynolds
Summary: A placental microsystem mimicking the structural phenotypes of a placental barrier was created to study the transport of pharmaceutical agents to the developing fetus. The formation of a continuous network of cell junctions and elongated microvilli under dynamic flow conditions was demonstrated, with fluid shear stress triggering microvilli formation. The concentrations of pharmaceutical agents in fetal channels were evaluated in coculture and control models, showing differences in drug concentrations between the two models. Gene expressions of epithelial and endothelial cells after drug administration and transport through the placental barrier were also reported.
ACS APPLIED BIO MATERIALS
(2022)
Article
Computer Science, Cybernetics
Ruisi Zhang, Jake J. Abbott
Summary: This paper characterizes the detection thresholds in six orthogonal modes of vibrotactile haptic display using a stylus. It is found that force signals and torque signals applied in different directions have different detection thresholds. Optimization techniques are used to determine models for describing frequency-dependent thresholds for styluses.
IEEE TRANSACTIONS ON HAPTICS
(2022)
Article
Nanoscience & Nanotechnology
Amir Niaraki, Marilyn C. McNamara, Reza Montazami, Nicole N. Hashemi
Summary: This study presents a graphene-based biosensor for real-time monitoring of dopaminergic neural cells. The biosensor characterizes cell adhesion and cytotoxicity factors through impedance spectroscopy. The results demonstrate the applicability of the impedance-based sensing for rapid screening of cytotoxic elements.
ACS APPLIED BIO MATERIALS
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
