Article
Chemistry, Multidisciplinary
Subir Paul, Arindam Banerjee
Summary: This study demonstrates the visible light induced continuous tuning of the fluorescence of carbon nanodots from yellow to cyan within two hours. The carbon dots are well characterized and have shown solid state fluorescence of different wavelengths, with a very low band gap. Additionally, the yellow emissive C-dots have been successfully utilized as a photocathode in metal free photo-electrochemical hydrogen evolution from water.
NANOSCALE ADVANCES
(2021)
Review
Chemistry, Multidisciplinary
Md Moniruzzaman, Jongsung Kim
Summary: Carbon dots (CDs) with unique and tunable multicolor photoluminescence (PL) emission have received great attention in recent years for their potential applications in the biomedical and optoelectronic fields. This review focuses on the advancement of synthesis and post-synthesis techniques for achieving tunable multicolor emission. Various synthesis strategies and post synthesis strategies have been discussed, including the selection of benzenoid precursor, acid/base treatment, optimization of reaction conditions, solvent engineering, and chemical doping. Furthermore, the need for a concise review article focusing on systematic synthesis and post synthesis strategies with PL mechanism elucidation is highlighted.
Article
Chemistry, Multidisciplinary
Run Wang, Hengyang Xiang, Siyuan Tu, Yan Li, Yihui Zhou, Haibo Zeng
Summary: Micro/mini displays play a significant role in the modern information society and have promising applications. In this study, passive-matrix and active-matrix mini-quantum dot light-emitting diodes (PM/AM-m-QLEDs) based on heavy-metal-free blue ZnTeSe/ZnS QDs were successfully fabricated using a full solution process. The m-QLEDs achieved high pixels per inch (PPI) suitable for televisions, computers, and mobile phones, and patterned display applications on both flexible and solid substrates. The low-cost advantage of solution-processed QDs could pave the way for low-cost displays.
Article
Chemistry, Physical
Mattia Salomone, Michele Re Fiorentin, Giancarlo Cicero, Francesca Risplendi
Summary: The study analyzes the stability and electronic properties of an InSe monolayer with point defects, showing the presence of deep defect states within the band gap. It predicts that Ge as a substitution impurity of Se could be a promising material for single-photon emitters due to its optical properties and strongly peaked spectrum in the near-infrared.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Analytical
Juan Yang, Dongmiao Qin, Na Wang, Yusheng Wu, Kanjun Fang, Biyang Deng
Summary: A novel sandwich electrochemiluminescence biosensor was developed for the sensitive detection of Afl42 using aggregation-induced electrochemiluminescence resonance energy transfer. The biosensor utilized silver nanoparticle-functionalized zinc metal-organic framework as the ECL donor and gold nanoparticle-functionalized zirconium organic framework as the acceptor. The method exhibited a linear detection range of 10 fg/mL to 100 ng/mL and a detection limit of 2.4 fg/mL. It also demonstrated good stability, repeatability, and specificity, making it a promising tool for disease biomarker detection.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Yamei Ding, Ping He, Shaohan Li, Bo Chang, Shengli Zhang, Zhehan Wang, Jiayi Chen, Jin Yu, Sanxie Wu, Haibo Zeng, Li Tao
Summary: The research has successfully achieved full-color emission from hexagonal boron nitride quantum dots by doping different amino ligands in different solvents, with the quantum yield reaching a record high of 32.27%.
Article
Chemistry, Analytical
Xinlu Li, Tongtong Zhu, Yuwei Du, Haiyang Yan, Ruhong Yan, Wen-Fei Dong, Li Li
Summary: Beta-carotene is a natural antioxidant with important effects on human growth and immunity. N-doped carbon quantum dots (O-CDs) were prepared for intracellular and in vitro detection of beta-carotene through co-heating carbonization. O-CDs showed good linear relationship with beta-carotene and exhibited targeting of lysosomes in cell imaging.
Article
Optics
Yaoyao Yang, Kangliang Peng, Yakun Deng, Youjun Zhao, Jinshui Ai, Xiao Min, Mengzhu Hu, Shuai Huang, Lixin Yu
Summary: This article successfully synthesized full-color-emission carbon quantum dots and found that the alterations of photoluminescence emission were mainly ascribed to surface states rather than particle size.
JOURNAL OF LUMINESCENCE
(2022)
Article
Chemistry, Multidisciplinary
Nan Li, Xuezhe Dong, Xugui Lv, Yunfei Li, Qingyu Ma, Ruifang Guan, Zheng Xie
Summary: We synthesized sulfur and nitrogen co-doped carbon dots with tunable fluorescence in both solutions and solid matrices, controlled by surface state. Furthermore, it can be used for trace water detection in various organic solvents, particularly in acetone, with a low limit of detection of 0.042%.
CHEMICAL COMMUNICATIONS
(2023)
Article
Multidisciplinary Sciences
Artem N. Abramov, Igor Y. Chestnov, Ekaterina S. Alimova, Tatiana Ivanova, Ivan S. Mukhin, Dmitry N. Krizhanovskii, Ivan A. Shelykh, Ivan V. Iorsh, Vasily Kravtsov
Summary: By using local deformation of monolayer WSe2, we have successfully created high-purity single-photon emitters. Through nanoindentation and atomic force microscopy, we have identified the single-photon emitting sites and reconstructed the details of the surrounding local strain potential. The experimental results suggest that the single-photon emission is likely due to strain-induced spectral shift of dark excitonic states and their hybridization with localized states of individual defects.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Saptarshi Mandal, Shakkira Erimban, Subhrajeet Banerjee, Snehasis Daschakraborty, Prolay Das
Summary: Through experiments and molecular dynamics studies, we found that the relationship between solvents and carbon dots has a significant impact on their red fluorescence. By controlling the solvent, we can achieve persistent red emission of carbon dots, which is of great significance for various applications.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Physics, Multidisciplinary
H. Wu, R. Richaud, J. -M. Raimond, M. Brune, S. Gleyzes
Summary: Circular Rydberg states have large mutual interactions and long lifetimes, but these lifetimes are cancelled by blackbody radiation-induced transfers at room temperature. In this study, we demonstrate a room-temperature lifetime of over 1 millisecond for a circular state with a principal quantum number of 60 in a laser-cooled atomic sample. This is achieved by using a simple plane-parallel capacitor that efficiently inhibits the blackbody radiation-induced transfers and provides large optical access to the atoms.
PHYSICAL REVIEW LETTERS
(2023)
Article
Chemistry, Physical
Francesco Maddalena, Aozhen Xie, Xin Yu Chin, Raihana Begum, Marcin E. Witkowski, Michal Makowski, Benoit Mahler, Winicjusz Drozdowski, Stuart Victor Springham, Rajdeep Singh Rawat, Nripan Mathews, Christophe Dujardin, Muhammad Danang Birowosuto, Cuong Dang
Summary: This study investigates the potential of lead halide perovskite nanocrystals in X-ray imaging applications, with CsPbBr3 NCs showing the best performance and being particularly suitable for fast-timing applications or particle detectors in high-energy physics.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Analytical
Yun Shu, Linyan Sun, Yan Wang, Dangqin Jin, Qin Xu, Xiaoya Hu
Summary: Through the synergistic effects of polymer surface ligand and silica encapsulation, highly stable and enhanced aqueous fluorescent CsPbBr3-mPEG@SiO2 NCs were synthesized, serving as a novel on-off-on fluorescent probe for highly sensitive and selective detection of mercury ions and glutathione in aqueous solutions. The fluorescent probe exhibits low detection limits, fast response time, and high accuracy, showing great potential in environmental and biological sensing.
Article
Materials Science, Multidisciplinary
Sam Masha, Oluwatobi Samuel Oluwafemi
Summary: In this study, blue and green emitting carbon-based quantum dots were successfully synthesized with good photoluminescence and high quantum yield. Structural characterizations revealed small, spherical, and highly crystalline materials, showing concentration dependent biocompatibility against mouse colon carcinoma and mouse bladder carcinoma cells.
Article
Chemistry, Multidisciplinary
Yang Lv, Mingrou Ma, Yucheng Huang, Yunsheng Xia
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Multidisciplinary
Jinxia Sun, Rong Luo, Yunsheng Xia
CHINESE CHEMICAL LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Mingrou Ma, Hui Zhu, Jing Ling, Suqin Gong, Yin Zhang, Yunsheng Xia, Zhiyong Tang
Article
Chemistry, Multidisciplinary
Jing Ling, Suqin Gong, Yunsheng Xia
ADVANCED MATERIALS INTERFACES
(2020)
Article
Chemistry, Physical
Yi Wang, Ge Guo, Jialin Gao, Zhibin Li, Xueer Yin, Changqing Zhu, Yunsheng Xia
CHEMISTRY OF MATERIALS
(2020)
Article
Materials Science, Multidisciplinary
Chuchu Wang, Ge Guo, Yi Wang, Xueer Yin, Hui Zong, Yunsheng Xia
Summary: Understanding the photoluminescence mechanism of carbon dots (C-dots) has been a challenge due to their indeterminate constitution and complicated composition/structure. This study presents a processing system for the separation of C-dots, resulting in the successful separation of two minimalistic C-dots with similar structure and optical properties. By analyzing the separated C-dots, it is revealed that their photoluminescence originates from uniform surface polycyclic aromatic hydrocarbon units and is not dependent on size or oxygen content. These C-dots exhibit bright and stable photoluminescence with molecular level accuracy, combining the advantages of small molecule dyes and photoluminescent nanomaterials.
ADVANCED OPTICAL MATERIALS
(2022)
Article
Chemistry, Analytical
Yi Wang, Zhibin Li, Ge Guo, Yunsheng Xia
Summary: In this study, a new fluorescent probe UE-C-dots was proposed to monitor hypochlorous acid in liver injury. The probe specifically detects hypochlorous acid through an excited state oxidation mechanism, without interference from other reactive oxygen/nitrogen species. Real-time tomographic imaging revealed distinct temporal and spatial differences in hypochlorous acid bursts caused by different stimuli, substantially expanding our understanding of the relationship between hepatic oxidative stress and physiological/pathological behaviors.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Menglei Wang, Fulin Jia, Jianxiao Gong, Yunsheng Xia
Summary: This article presents an in situ decomposition-assembly strategy for the versatile fabrication of metal sulfide supraparticles (SPs), which have various applications in biomedical, catalysis, and battery materials. The strategy involves the reaction of cysteine molecules and metal cations to form coordination polymers, which are then decomposed to generate small-sized metal sulfide nanocrystals. These nanocrystals self-assemble each other driven by the elimination of high surface energy and van der Waals attraction, leading to the formation of SP products. The size of SPs can be easily tuned by adjusting the proportion of cysteine and metal ions, and different properties and hybrid structures can be achieved.
NANOSCALE ADVANCES
(2023)
Article
Chemistry, Analytical
Yi Wang, Zhibin Li, Ge Guo, Yunsheng Xia
Summary: We successfully monitor the oxidative stress processes in liver injury by using unit-emitting carbon dots (UE-C-dots) as fluorescent probes, which can specifically determine hypochlorous acid (HClO) molecules. Real-time tomographic imaging shows distinctly different HClO bursts in both temporal and spatial dimensionalities caused by different stimuli. The measurement and analysis of temporal information substantially extend our understanding on the relationships of hepatic oxidative stress and corresponding physiological/pathological behaviors.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Analytical
Zhu Hui, Xia Yun-Sheng
Summary: Supraparticles (SPs) are nano-agglomerates self-assembled by same or different kinds of individual inorganic nanocrystals, exhibiting collective properties and/or synergistic effects. With diverse shapes and devisable spatial structures, SPs provide multi-scale and multi-dimensional possibilities for interactions with various biological systems, showing a variety of application potentials in bio-sensing, bio-imaging, diagnosis, and therapy. This review summarizes the progress of SPs fabrication, properties, and their applications in the field of bioimaging in recent years, as well as discusses the main problems and future development in their fabrication and applications in bio-medicine.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Rong Luo, Yunsheng Xia
Summary: The study introduces a self-assembly strategy to fabricate fluorescent CdS supraparticles for mitochondria targeting applications. By manipulating the length of the cationic surfactant molecules, the localization capacity of the supraparticles in mitochondria can be enhanced.
JOURNAL OF ANALYSIS AND TESTING
(2021)
Review
Chemistry, Physical
Yunyun Ling, Yunsheng Xia
ACTA PHYSICO-CHIMICA SINICA
(2020)
Article
Materials Science, Biomaterials
Yue Wang, Yunsheng Xia
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Article
Chemistry, Multidisciplinary
Biao Wang, Ruirui Li, Ge Guo, Yunsheng Xia
CHEMICAL COMMUNICATIONS
(2020)
Article
Chemistry, Multidisciplinary
Yunyun Ling, Li Li, Xiurong Liang, Yunsheng Xia
CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE
(2020)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
