Article
Nanoscience & Nanotechnology
Devi Wahyuningtyas, Wen-Hao Chen, Ruei-Yu He, Yung-An Huang, Chia-Kang Tsao, Yu-Jung He, Chu-Yi Yu, Po-Chao Lu, Yu-Cai Chen, Sheng-Hann Wang, Ka Chon Ng, Bryan Po-Wen Chen, Pei-Kuen Wei, Jiun-Jie Shie, Chun-Hong Kuo, Y. Henry Sun, Joseph Jen-Tse Huang
Summary: The researchers designed and synthesized a polyglutamine-specific gold nanoparticle complex that targeted mHtt and alleviated its toxicity. The complex was able to disassociate fibrillary aggregates from polyQ peptides and reduce beta-sheet content in a concentration-dependent manner. Additionally, the complex was shown to penetrate cells, bind to cytosolic mHtt proteins, dissociate mHtt inclusions, reduce mHtt oligomers, and ameliorate mHtt-induced toxicity, suggesting potential therapeutic strategies against Huntington's disease.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Biochemical Research Methods
Renfei Ma, Shangfu Li, Luca Parisi, Wenshuo Li, Hsien-Da Huang, Tzong-Yi Lee
Summary: Phosphorylation is a crucial mechanism for regulating protein activities, but experimental determination of kinase-specific phosphorylation sites is time-consuming and expensive. This study aims to create predictive models for understudied kinases by leveraging relevant sources of similarities. Results demonstrate that 82 out of 116 understudied kinases were predicted with adequate performance, proving the reliability of web-like predictive networks in capturing patterns in such kinases.
BRIEFINGS IN BIOINFORMATICS
(2023)
Article
Biochemistry & Molecular Biology
Yangjun Feng, Xiaolin Li, Dongsheng Ji, Jialei Tian, Qian Peng, Yuzhen Shen, Yuliang Xiao
Summary: The purpose of this study was to develop a transmembrane peptide-chondroitin sulphate-gold nanoparticle (TAT-CS@Au) delivery system for an anti-Alzheimer's disease (AD) drug. TAT-CS@Au demonstrated excellent cellular uptake, inhibited A beta 1-40 accumulation, reduced oxidative stress damage and aberrant tau phosphorylation, and suppressed the expression of inflammatory factors. These findings suggest that TAT-CS@Au could be a promising multi-target anti-AD drug with good cell permeability.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mohammad Khavani, Aliyeh Mehranfar, Mohammad R. K. Mofrad
Summary: The interactions between 10 short peptides and gold nanoparticles of different diameters have been studied using molecular dynamics simulations. The results show that gold nanoparticles significantly affect the stability and conformational properties of the peptides. The size of the gold nanoparticles and the amino acid sequences of the peptides play important roles in the stability of the peptide-gold nanoparticle complexes. The study provides new insight into peptide interaction with gold nanoparticles from a molecular viewpoint, which can be valuable for designing biomaterials based on peptides and gold nanoparticles.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Engineering, Biomedical
Masayoshi Tanaka, Mirei Hayashi, Lucien Roach, Yuka Kiriki, Tetsuya Kadonosono, Takahiro Nomoto, Nobuhiro Nishiyama, Jonghoon Choi, Kevin Critchley, Stephen D. Evans, Mina Okochi
Summary: The study explored the synthesis of triangular gold nanoplates using peptides, demonstrating control over nanoplate size and properties by adjusting peptide concentration. These nanoplates showed promising potential as photothermal therapeutic agents and indicated the feasibility of synthesizing circular gold nanoplates using peptides.
ACTA BIOMATERIALIA
(2021)
Review
Chemistry, Physical
Wenchao Yang, Qiuxiang Yin, Chun-Long Chen
Summary: The review discusses the relationship between biomineralization and inorganic crystal formation, as well as the research progress in using peptoids to control the formation of inorganic crystals. The focus is on correlating the side chain chemistry of peptoids with the morphological and kinetic control of inorganic (nano)crystals.
CHEMISTRY OF MATERIALS
(2021)
Article
Nanoscience & Nanotechnology
Mohammad Akrami, Shabnam Samimi, Mohsen Alipour, Hassan Bardania, Sorour Ramezanpour, Niayesh Najafi, Saman Hosseinkhani, Mojtaba Kamankesh, Ismaeil Haririan, Fatemeh Hassanshahi
Summary: The study successfully developed a cancer-targeting nanoparticle platform with higher affinity to breast cancer cells by combining peptides with AuNPs, showing improved uptake and anti-tumor efficiency in vivo.
Article
Biophysics
McKenzie B. Riley, Evan Strandquist, Christopher S. Weitzel, Jeremy D. Driskell
Summary: Research shows that the thiolated analog of a protein has a greater affinity for gold nanoparticles (AuNPs) and is able to form a robust hard corona, maintaining structure and function, compared to the unmodified protein which denatures with prolonged exposure to AuNPs resulting in loss of enzymatic function.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Multidisciplinary Sciences
Fang Zheng, Elena Lian, Gaby Ramirez, Carley McAlister, Shuo Zhou, Wen Zhang, Chunming Liu, Rushika Perera, Chang-Guo Zhan
Summary: In this study, cytotoxicity assays were performed to examine the potential cytoprotective activity of nicotine against SARS-CoV-2 infection. The results demonstrated that nicotine had no significant cytoprotective activity against SARS-CoV-2 infection in these cells.
Article
Multidisciplinary Sciences
Fang Zheng, Elena Lian, Gaby Ramirez, Carley McAlister, Shuo Zhou, Wen Zhang, Chunming Liu, Rushika Perera, Chang-Guo Zhan
Summary: This study conducted cytotoxicity assays in Vero E6 cells to examine the potential cytoprotective activity of nicotine against SARS-CoV-2 infection. The results demonstrated for the first time that nicotine had no significant cytoprotective activity against SARS-CoV-2 infection in these cells.
Article
Chemistry, Analytical
Hanie Safarpour, Hasan Majdi, Ali Masjedi, Abdol Sattar Pagheh, Maria de Lourdes Pereira, Sonia M. Rodrigues Oliveira, Ehsan Ahmadpour
Summary: The study introduces a novel enhanced immuno-dot-blot assay for diagnosing cystic echinococcosis, utilizing a sandwich complex of a gold nanoprobe and hydatid cyst antigen. This method provides a simple and rapid diagnostic technique without the need for expensive equipment.
Article
Chemistry, Multidisciplinary
Peter R. Christenson, Manci Li, Gage Rowden, Peter A. Larsen, Sang-Hyun Oh
Summary: Misfolded proteins associated with neurodegenerative diseases can accumulate in tissues or circulate in biological fluids before the onset of clinical symptoms, making them ideal diagnostic targets. Adding nanoparticles to the RT-QuIC assay improves its speed and sensitivity, which is crucial for diagnostic application.
Article
Chemistry, Multidisciplinary
Karolina Majsterkiewicz, Artur P. Biela, Sourav Maity, Mohit Sharma, Bernard M. A. G. Piette, Agnieszka Kowalczyk, Szymon Gawel, Soumyananda Chakraborti, Wouter H. Roos, Jonathan G. Heddle
Summary: The structure of an artificial protein cage triggered by gold nanoparticles was successfully predicted, and it was discovered that each cage contains gold nanoparticles, which can be used to achieve regular arrangement of the nanoparticles.
Article
Chemistry, Medicinal
Christian Borgo, Luca Cesaro, Tsuyoshi Hirota, Keiko Kuwata, Claudio D'Amore, Thomas Ruppert, Renata Blatnik, Mauro Salvi, Lorenzo A. Pinna
Summary: CK2, a protein kinase with pleiotropic functions, is implicated in global human pathologies, particularly cancer. Selective inhibitors like CX4945 and GO289 show promise in controlling the CK2-dependent phosphoproteome.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Veronika M. Shoba, Dhanushka N. P. Munkanatta Godage, Santosh K. Chaudhary, Arghya Deb, Sachini U. Siriwardena, Amit Choudhary
Summary: Phosphorylation-inducing chimeric small molecules (PHICS) can enable protein kinase C (PKC) to have new activities, such as inducing inhibitory neo-phosphorylations on a variant and phosphorylating cytosol-based neo-substrates. PKC with PHICS can also induce death of chronic myeloid leukemia cells. Synthetic chemistry has the power to expand the chemical and functional diversity of proteins in cells using bifunctional molecules.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Riki Toita, Eiko Shimizu, Masaharu Murata, Jeong-Hun Kang
Summary: The study suggests that phosphatidylserine-containing liposomes can promote the generation of M2-like macrophages to protect against pressure ulcer formation and accelerate healing. Older animals demonstrate slower wound healing, but PSL treatment significantly accelerates wound closure.
JOURNAL OF CONTROLLED RELEASE
(2021)
Article
Materials Science, Biomaterials
Chan Woo Kim, Riki Toita, Jeong-Hun Kang, Takeshi Mori, Akihiro Kishimura, Yoshiki Katayama
Summary: The study explores a protein kinase C alpha (PKC alpha)-responsive gene carrier that selectively responds to malfunctioning intracellular signaling in cancer cells, showing potential for cancer-specific gene delivery and therapy.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Takahito Kawano, Yoko Tachibana, Junichi Inokuchi, Jeong-Hun Kang, Masaharu Murata, Masatoshi Eto
Summary: This study aimed to investigate the presence of activated protein kinase C alpha (PKC alpha) in urine samples and the possibility of PKC alpha as a urinary biomarker for bladder cancer diagnosis. Results showed that activated PKC alpha was present at higher levels in bladder cancer tissues than in normal bladder tissues, and also observed at higher levels in urine samples collected from orthotopic xenograft mice carrying human bladder cancer cells. These findings suggest that activated PKC alpha can potentially serve as a urinary biomarker for diagnosing bladder cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Pharmacology & Pharmacy
Takahito Kawano, Junichi Inokuchi, Masatoshi Eto, Masaharu Murata, Jeong-Hun Kang
Summary: PKC is a family of important kinases classified into three subfamilies based on structural and activation characteristics, and used for understanding intracellular signaling pathways and treating related diseases. While PKC inhibitors in clinical trials for cancers did not show significant benefits, there is still potential for their application in research on other diseases.
Article
Chemistry, Multidisciplinary
Mai Shinohara, Yuya Ashikaga, Wei Xu, Sunnam Kim, Tuyoshi Fukaminato, Takuro Niidome, Seiji Kurihara
Summary: This study investigated the photochemical switching of cytotoxicity by using spiropyran compounds with pyridinium and alkyl groups. The results showed that the two isomers of SP6 (MC and SP) displayed different cytotoxicity under visible light irradiation at different concentrations, achieving the photochemical switching of cytotoxicity. These findings are important for the development of novel photochemotherapy drugs.
Article
Chemistry, Multidisciplinary
Emi Takeda, Wei Xu, Mitsuhiro Terakawa, Takuro Niidome
Summary: Research showed that triangular silver nanoparticles coated with silica exhibited strong antimicrobial activity under high laser power, but crystallization of the silica layer at moderate power levels led to decreased antimicrobial activity.
Article
Chemistry, Physical
Makoto Sasaki, Wei Xu, Yuki Koga, Yuki Okazawa, Akira Wada, Ichiro Shimizu, Takuro Niidome
Summary: The study found that coating the magnesium alloy stent with parylene C can improve its corrosion resistance, ensuring its stability in cell culture medium. This provides new possibilities for the development of bioresorbable magnesium alloy stents in clinical applications.
Article
Pharmacology & Pharmacy
Wei Xu, Makoto Sasaki, Takuro Niidome
Summary: Drug-eluting stents (DESs) are commonly used for the treatment of coronary artery disease. The evolution of the drug-eluting layer on the stent's surface is crucial for its functionality. Using biodegradable polymers is an attractive approach as it reduces the risk of late thrombosis after stent implantation. Understanding drug-release behavior from these polymers is important for improving the safety and efficacy of stent treatments.
Article
Chemistry, Multidisciplinary
Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Summary: Advances in drug delivery systems have allowed specific delivery of drugs to target cells. This study demonstrates the selective delivery of SubAB to macrophages and its anti-inflammatory effects by modifying it with PLGA nanoparticles. These findings provide a useful technique for protein delivery to macrophages and support the application of drug delivery systems in the treatment of inflammatory diseases.
Article
Engineering, Biomedical
Riki Toita, Jeong-Hun Kang, Akira Tsuchiya
Summary: This study developed a novel strategy using artificial apoptotic cell mimetics (phosphatidylserine liposomes; PSLs) to promote tissue repair and tissue-to-biomaterial integration by inducing M1-to-M2 macrophage transition, with bone as the model tissue. The results showed that PSL-multilayer-coated implants enhanced de novo bone formation and bone-to-implant integration, triggering the proper generation and activation of bone-forming osteoblasts and bone-resorbing osteoclasts. These findings demonstrate the potential of PSL-multilayers in bone regeneration and have significant implications for the design of new immunomodulatory biomaterials.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Multidisciplinary
Yuko Sato, Daisuke Asa, Keiko Terada, Jeong-Hun Kang, Takeshi Mori, Takuro Niidome, Hideki Nakashima, Yoshiki Katayama
Summary: This study demonstrates that by increasing the mobility of DNA strands, the preinitiation complex can better access chromatin-packaged DNA for transcriptional initiation.
Review
Health Care Sciences & Services
Waliul Islam, Takuro Niidome, Tomohiro Sawa
Summary: This article provides an overview of the development of the first polymer drug, SMANCS, in 1979, and the discovery of the enhanced permeability and retention effect (EPR effect) in 1986. The article discusses the application of EPR effect in nanomedicine and recent research progress.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Nanoscience & Nanotechnology
Waliul Islam, Hiroyasu Tsutsuki, Katsuhiko Ono, Ayaka Harada, Kozo Shinozaki, Takuro Niidome, Jun Fang, Tomohiro Sawa
Summary: The development of a multifunctional water-soluble anticancer polymer drug, the SGB complex, has been shown to have tumor-selective accumulation and therapeutic effects on cancer cells by inhibiting lactate secretion. Chemical structure analysis confirmed the rational design of the SGB complex and its stability in the presence of serum.
ACS APPLIED BIO MATERIALS
(2022)
Article
Nanoscience & Nanotechnology
Ayaka Harada, Wei Xu, Katsuhiko Ono, Hiroyasu Tsutsuki, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Summary: In this study, the B subunit of subtilase cytotoxin (SubB) was conjugated to silver nanoplates (AgNPLs) for use as an antibacterial drug against intracellularly infecting Salmonella typhimurium (S. typhimurium). The modification of AgNPLs with SubB improved their dispersion stability and antibacterial activity. The SubB modification enhanced the cellular uptake of AgNPLs, leading to the killing of intracellularly infecting S. typhimurium.
ACS APPLIED BIO MATERIALS
(2023)
Article
Engineering, Biomedical
Riki Toita, Masahiro Kitamura, Akira Tsuchiya, Jeong-Hun Kang, Shinjiro Kasahara
Summary: "A new surface engineering strategy is described, which involves the release of phosphatidylserine liposomes (PSLs) from an implant coating to modify macrophage phenotype and mitigate foreign body reactions (FBRs), resulting in improved tissue healing. Unlike other therapeutic approaches, PSL-multilayered coatings also promote muscle regeneration."
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
