Article
Chemistry, Physical
Zhiyang Guo, Yi Sun, Lirui Zhang, Qian Ding, Wei Chen, Hao Yu, Qingyun Liu, Min Fu
Summary: A novel surface imprinted core-shell nanorod was developed for glycoprotein extraction, showing high binding capacity and fast mass transfer rate with outstanding selectivity towards the template protein, suggesting broad application prospects in glycoprotein recognition, biomedical research, and clinical diagnosis.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Polymer Science
Maria de los Milagros Citta, Federico Fookes, Carlos Busatto, Diana Estenoz, Natalia Casis
Summary: Molecular imprinting technology has shown significant advances in the recognition and separation of small molecules. In this work, calcium carbonate microparticles were used as a support for the preparation of molecularly imprinted polymers (MIPs) targeting the model protein bovine serum albumin (BSA). The microparticles exhibited a rhombohedral morphology and a narrow size distribution. The study demonstrated the potential use of the developed microparticles for protein separation in applications such as stationary phase in liquid chromatography.
IRANIAN POLYMER JOURNAL
(2023)
Article
Chemistry, Analytical
Kaijia Xu, Qingzhou Dai, Yuzhi Wang, Kai Chen, Yinyin Qian
Summary: A novel ionic liquid-crosslinked molecularly imprinted polymer (IL-Fe3O4@AAm-MIP) was successfully fabricated for the selective adsorption of lysozyme. The IL-Fe3O4@AAm-MIP exhibited a high adsorption capacity and imprinting factor, and showed favorable selectivity towards lysozyme. Moreover, the IL-Fe3O4@AAm-MIP was able to specifically capture lysozyme from complex protein mixtures and actual biological samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Yuxuan Ma, Yuan Xu, Hui Chen, Jifeng Guo, Xiao Wei, Lihui Huang
Summary: The combination of mesoporous silica with imprinted polymers enhances the adsorption efficiency of dichlorophen, reaching equilibrium rapidly and utilizing a multi-molecular layer adsorption mechanism.
GREEN PROCESSING AND SYNTHESIS
(2021)
Article
Chemistry, Physical
Jingyang Zhao, Yucheng Li, Huatai Zhu, Guifang Li, Lingling Kang, Jing Liu, Jing He, Jiandu Lei, Luying Wang, Qiong Yan
Summary: A novel MXene-copolymeric molecularly imprinted hydrogel (FMMIH) with temperature/pH dual response and photothermal conversion performance has been successfully prepared for selective recognition of cis-diol compounds. The hydrogel, incorporating functionalized MXene, displays improved mechanical properties and efficient photothermal conversion. Utilizing dual recognitions of functional groups and geometric space, FMMIH can controllably capture and release cis-diol compounds like ginsenoside Rb1.
Article
Chemistry, Applied
Noha Amaly, Ahmed Y. El-Moghazy, Gang Sun
Summary: A nanofibrous membrane based MIP was developed for selective separation of lysozyme, showing high adsorption capacity and imprinting factor. The released lysozyme displayed good bioactivity, efficiently decomposing bacterial cell wall.
Article
Chemistry, Analytical
Jiaxin Ma, Cheng He, Ziru Lian
Summary: A highly efficient sample clean-up and preconcentration method using novel magnetic molecularly imprinted polymers (MMIPs) was developed for selective entrapment and rapid detection of rhodamine B from seawater samples. The MMIPs showed high affinity and selectivity for rhodamine B. The method presented a wide linear response range and low limit of detection, and proved to be an attractive and sensitive alternative for rapid analysis of organic dyes in complex seawater matrix.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Yujuan Ren, Juntao Zhou, Muhammad Mujahid Ali, Xue Zhang, Lianghai Hu
Summary: This article introduces an enrichment method based on molecular imprinting technology, which can specifically recognize and capture phosphorylated peptides. Through experiments, it has been proved that this method has high specificity, strong affinity, and good stability, and can be used for the enrichment of unique phosphorylated peptides.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Qianjin Li, Tingting Wang, Yu Jin, Celina Wierzbicka, Fenying Wang, Jianlin Li, Borje Sellergren
Summary: A novel sedimentation-based solid phase imprinting strategy was introduced to prepare highly selective MIP nanoparticles targeting phospholipids. The method showed high yield, good specificity, and the ability to recognize and recover phospholipids in human serum.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Review
Polymer Science
Chengya Dong, Hongxing Shi, Yuanrui Han, Yuanyuan Yang, Ruixin Wang, Jiying Men
Summary: Surface molecular imprinting technology (SMIT) has attracted extensive attention and been applied in various fields due to its desired selectivity and fast mass transfer rate, but faces challenges such as obtaining pure templates and high cost of using noble metals.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Biomedical
Sinem Diken Gur, Monireh Bakhshpour, Nilay Bereli, Adil Denizli
Summary: The study aimed to develop a novel biocompatible and cost-effective cryogel membrane with enhanced antimicrobial properties for various applications. Lysozyme imprinted cryogel membranes prepared using molecular imprinting technique showed antibacterial effects against both Gram-positive and Gram-negative bacteria.
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
(2021)
Article
Chemistry, Physical
Xiaowei Li, Yan Zhao
Summary: This study reports the use of molecularly imprinted nanoparticles as catalysts that utilize their environmental chirality to control the stereochemical outcomes. The catalytic reactions conducted in water at room temperature show high yields and excellent enantioselectivity.
JOURNAL OF CATALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Mingqi Wang, Shixin Fa, Guoxian Zhang, Jiate Yu, Qiuyu Zhang
Summary: A novel nanosphere (MS@PTL-g-PNIPAM) is designed, which is temperature and pH responsive and can dynamically reversibly crosslink/de-crosslink. With the help of this technology, the nanospheres can be repeatedly programmed into protein imprinted nanospheres towards different target proteins. This study achieves the specific separation of different target proteins from protein mixture and real bovine blood, providing convenience for protein imprinted materials to be used in various applications.
Article
Chemistry, Analytical
Dawei Wang, Shenghao Jiang, Yuanyuan Liang, Xiaobin Wang, Xuming Zhuang, Chunyuan Tian, Feng Luan, Lingxin Chen
Summary: A novel MIP-ECL sensor based on MPA-Cu NCs was developed for selective detection of ENR, showing promising applications in biological analysis and environmental water monitoring. The sensor exhibited good recovery rates and detection performance in biological and lake water samples.
Article
Chemistry, Multidisciplinary
Xiaojiao Yuan, Rebeca Ferrer-Campos, Felipe A. Garces-Pineda, Katherine Villa
Summary: Surface engineering of light-driven BiVO4 microswimmers with molecular imprinting polymerization enables selective self-propulsion and degradation of target molecules. This study offers a unique strategy to enhance the motion capabilities of single-component photocatalytic microswimmers in a specific chemical environment.
Article
Chemistry, Analytical
Kai Huang, Bingbing Li, Feng Zhou, Surong Mei, Yikai Zhou, Tao Jing
ANALYTICAL CHEMISTRY
(2016)
Article
Engineering, Environmental
Kai Huang, Ying Chen, Feng Zhou, Xiaoya Zhao, Jiafa Liu, Surong Mei, Yikai Zhou, Tao Jing
JOURNAL OF HAZARDOUS MATERIALS
(2017)
Article
Engineering, Environmental
Xiu Wang, Kai Huang, Ying Chen, Jiafa Liu, Shan Chen, Jianlei Cao, Surong Mei, Yikai Zhou, Tao Jing
JOURNAL OF HAZARDOUS MATERIALS
(2018)
Article
Multidisciplinary Sciences
Yusun Zhou, Yun Tao, Huarong Li, Tingting Zhou, Tao Jing, Yikai Zhou, Surong Mei
SCIENTIFIC REPORTS
(2016)
Article
Multidisciplinary Sciences
Feng Zhou, Yue Wang, Wei Wu, Tao Jing, Surong Mei, Yikai Zhou
SCIENTIFIC REPORTS
(2016)
Article
Multidisciplinary Sciences
Bingbing Li, Feng Zhou, Kai Huang, Yipei Wang, Surong Mei, Yikai Zhou, Tao Jing
SCIENTIFIC REPORTS
(2017)
Article
Environmental Sciences
Tingting Zhou, Yun Tao, Yinghu Xu, Dan Luo, Liqin Hu, Jingwen Feng, Tao Jing, Yikai Zhou, Surong Mei
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2018)
Article
Environmental Sciences
Hongxing Zhang, Zhenxing Mao, Kai Huang, Xiu Wang, Ling Cheng, Lingshuai Zeng, Yikai Zhou, Tao Jing
ENVIRONMENT INTERNATIONAL
(2019)
Article
Chemistry, Analytical
Lingshuai Zeng, Hairong Cui, Jianlei Chao, Kai Huang, Xiu Wang, Yikai Zhou, Tao Jing
Article
Environmental Sciences
Ling Cheng, Kai Huang, Hairong Cui, Xiu Wang, Hongxing Zhang, Lingshuai Zeng, Xiu Zhang, Bingmao Wang, Yikai Zhou, Tao Jing
SCIENCE OF THE TOTAL ENVIRONMENT
(2020)
Article
Engineering, Environmental
Kai Huang, Xiu Wang, Hongxing Zhang, Lingshuai Zeng, Xiu Zhang, Bingmao Wang, Yikai Zhou, Tao Jing
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2020)
Article
Chemistry, Analytical
Xiu Wang, Kai Huang, Hairong Cui, Hongxing Zhang, Lingshuai Zeng, Yikai Zhou, Tao Jing
SENSORS AND ACTUATORS B-CHEMICAL
(2020)
Article
Engineering, Environmental
Xiu Wang, Kai Huang, Lingshuai Zeng, Xiu Zhang, Danqi Cheng, Ruifang Li, Yikai Zhou, Tao Jing
Summary: This study presents a method for the simultaneous determination of 103 SVOCs within a single chromatographic run lasting 36.65 minutes. The developed protocol showed good recovery rates and stability, and was successfully applied to the analysis of real serum samples.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2021)
Article
Materials Science, Biomaterials
Long Jiang, Tao Jing, Xiantao Shen
Summary: Molecularly imprinted wax (MIW) spheres were successfully prepared using octadecanoic acid as the functional monomer and wax as the matrix. The MIW spheres displayed remarkable molecular recognition ability and high selectivity towards the template. The as-synthesized MIW could be dissolved in n-hexane or melted by heating for subsequent fluorescence and mass spectrum analysis without the target elution process.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Multidisciplinary
Tingting Zhou, Xiaoya Zhao, Yinghua Xu, Yun Tao, Dan Luo, Liqin Hu, Tao Jing, Yikai Zhou, Peng Wang, Surong Mei
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)