期刊
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
卷 56, 期 3, 页码 321-323出版社
WILEY
DOI: 10.1111/jcpp.12400
关键词
Brain development; neuropsychiatric disorders; neuroimaging; connectome; DOHad
资金
- [F31 MH 094000]
- [F32 MH 105283]
- [R00 MH091238]
- [R01 MH096773]
Vertes and Bullmore's article lays a framework for applying connectomics, the study of brain function from the perspective of underlying network organization, to advance understanding of healthy and maladaptive brain development. They elucidate the power of connectomics for bridging both different levels of analysis (e.g. from synapses to brain regions) and multiple academic fields. In this commentary, we highlight important themes and remaining questions stemming from Vertes and Bullmore's work, including: (a) the application of connectomics in the context ofintegrating analyses across multiple spatial and temporal dimensions, (b)the extent to which connectomics might be applied in translational and clinical studies of development, (c) growth connectomics and the Developmental Origins of Health and Disease (DOHaD) hypothesis, and (d) the importance and complexity of sound methodological practices in applying connectomics to developmental and clinical science. Ongoing work in these areas will be important for fulfilling the promise of connectomics as a bridge between neuroscience, developmental science, and translational and clinical research. Read the full article at doi:
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