Article
Microbiology
Alessandra Alessiani, Gianfranco La Bella, Adelia Donatiello, Gilda Occhiochiuso, Simona Faleo, Antonella Didonna, Luigi D'Attoli, Patrizia Selicato, Carmine Pedarra, Giovanna La Salandra, Maria Emanuela Mancini, Pietro Di Taranto, Elisa Goffredo
Summary: Salmonella Infantis is a common serovar in broilers and human salmonellosis cases. Six strains of Infantis were isolated from broiler litter and carcasses between 2018 and 2022 and were characterized for their phenotype, antibiotic resistance, and genomic profiles. The results showed that these strains were multidrug-resistant and belonged to the Infantis serotype and sequence type ST32. The presence of a new variant of S. Infantis is significant as it may expand the population and pose a public health concern.
Article
Biochemistry & Molecular Biology
Sruthi Sundaresan, Thenmalarchelvi Rathinavelan
Summary: A user-friendly web tool called SSP is developed to predict the serotypes of Salmonella species. It has an accuracy of 99.72% and can identify new species, making it valuable in the surveillance of Salmonella species.
JOURNAL OF MOLECULAR BIOLOGY
(2023)
Article
Microbiology
Kabiru Olusegun Akinyemi, Christopher Oladimeji Fakorede, Joerg Linde, Ulrich Methner, Gamal Wareth, Herbert Tomaso, Heinrich Neubauer
Summary: This study identified and verified the clonal relationship of Nigerian non-typhoidal Salmonella strains isolated from humans, animals, and the environment. Identical Salmonella sequence types were found in human, animal, and environmental samples in the same locality, demonstrating the potential of the applied tools to trace back outbreak strains.
Review
Infectious Diseases
Daniel Diaz, Pavel Eduardo Hernandez-Carreno, Diana Zuleika Velazquez, Miguel Angel Chaidez-Ibarra, Arnulfo Montero-Pardo, Francisco Antonio Martinez-Villa, Adrian Canizalez-Roman, Vianney Francisco Ortiz-Navarrete, Rene Rosiles, Soila Maribel Gaxiola, Francisco Jimenez-Trejo
Summary: The prevalence of NTS in poultry samples is high and varies significantly among different countries, with the highest values in Mexico, the United States, and Canada. There is a concerning prevalence of antimicrobial resistance among zoonotic serovars, with distinct patterns of serovar distribution across countries.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Biotechnology & Applied Microbiology
Matthew W. Quinn, Nicola F. Linton, Carlos G. Leon-Velarde, Shu Chen
Summary: Current detection protocols for Salmonella serovars are limited and often miss less abundant serovars in a sample. However, the CRISPR-SeroSeq method can accurately detect multiple serovars without the need for culture isolation. This method successfully detected 34 serovars in pure cultures and 25 different serovars in environmental samples from poultry farms, highlighting its effectiveness in surveillance.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Biochemical Research Methods
K. Mohanapriya, Himani Agri, Subbaiyan Anbazhagan, Damini Khawaskar, Varsha Jayakumar, Michael V. Lalrinzuala, K. M. Himani, I Sophia, Asok K. Mariappan, Pallab Abhishek, Viswas Konasagara Nagaleekar, Dharmendra K. Sinha, Pallab Chaudhuri, Vinod K. Chaturvedi, Bhoj R. Singh, Prasad Thomas
Summary: Salmonella species are a group of Gram-negative bacteria with numerous serovars, some of which are associated with diseases in livestock and humans. Molecular methods, such as PCR, have been applied to predict the serovars by detecting specific genetic elements. In this study, two multiplex PCR assays were developed to detect important Salmonella serovars associated with poultry in India. The assays showed high specificity and applicability for routine diagnosis.
JOURNAL OF MICROBIOLOGICAL METHODS
(2023)
Article
Biochemical Research Methods
Sepideh Fathi, Nazila Jalilzadeh, Mohammad Amini, Dariush Shanebandi, Behzad Baradaran, Fatemeh Oroojalian, Ahad Mokhtarzadeh, Prashant Kesharwani, Amirhossein Sahebkar
Summary: Due to its high mortality rates, typhoid fever continues to be a major health problem worldwide, especially in developing countries. However, the lack of accurate diagnostic tests and the similarity of typhoid symptoms to other diseases pose a challenge in accurately diagnosing typhoid fever. To address this issue, researchers have developed a Surface Plasmon Resonance (SPR) based biosensor that can specifically detect Salmonella typhi through DNA hybridization. The results showed that the biosensor could detect synthetic target sequences at a concentration of 10 nM and PCR products at a concentration of 1 nM. Additionally, the biosensor was able to accurately distinguish between complementary sequences and sequences with one base mismatch. The chip's surface can be regenerated and reused for consecutive diagnoses using NaOH solution. These findings highlight the potential of the designed biosensor for the detection of Salmonella typhi.
ANALYTICAL BIOCHEMISTRY
(2023)
Article
Gastroenterology & Hepatology
Nicholas C. Bank, Vaidhvi Singh, Alex Rodriguez-Palacios
Summary: In this study, a classification system based on the rfbA gene was developed to characterize the pathogenicity and probiotic properties of Pdis and Bacteroidetes. Analysis of 14 Pdis complete genomes revealed four lineages within Pdis. In addition, a PCR primer strategy for other Bacteroidetes was proposed. Comparative analysis confirmed the high discriminant power of rfbA.
Article
Chemistry, Physical
Kotesh Kumar Mandari, Namgyu Son, Yang Soo Kim, Misook Kang
Summary: The study focuses on the development of stable quaternary material for solar-to-hydrogen conversion, with CuS-AgVO3/Ag-TNR heteronanostructures showing significantly improved photocatalytic hydrogen production activity. The accelerated charge transfer pathway and proposed photocatalytic mechanism provide new insights for designing high-performance materials for clean renewable H-2 energy conversion.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Spectroscopy
Chenghao Tang, Eungyeong Park, Shuang Guo, Sila Jin, Lina Zhao, Lei Chen, Young Mee Jung
Summary: Ag-ZnX composites coated on polystyrene arrays were fabricated using cosputtering technology. The doping of ZnX decreased the carrier densities and caused a redshift in the surface plasmon resonance of Ag. The study opens up a new path for designing metal-semiconductor composites with controllable carrier density.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Jia-Li Chen, Xia-Guang Zhang, De-Yin Wu
Summary: Small gold nanoparticles (GNPs) exhibit special catalytic activity for hydrogen (H-2) dissociation reaction. Simulation experiments revealed that H-2 dissociation on gold clusters occurs through a homolytic cleavage reaction process, and both light irradiation and water environment can assist and promote the dissociation process.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
(2023)
Article
Biotechnology & Applied Microbiology
Maria Grazia Aruta, Elisa Lari, Daniele De Simone, Bianca Semplici, Claudia Semplici, Helen Dale, Esmelda Chirwa, Innocent Kadwala, Maurice Mbewe, Happy Banda, Miren Iturriza-Gomara, Melita Gordon, Tonney Nyirenda, Pietro Piu, Mariagrazia Pizza, Francesco Berlanda Scorza, Silvia Grappi, Rocio Canals, Omar Rossi
Summary: This study presents a customized enzyme-linked immunosorbent assay (ELISA) for quantification of antibodies against Salmonella Typhimurium and Salmonella Enteritidis O-antigens in human samples. The assay is simple, sensitive, specific, and cost-effective, making it suitable for various laboratories, including resource-limited settings.
Article
Microbiology
Estelle Muhle, Chloe Abry, Priscilla Leclerc, Gogoa-Marthe Goly, Alexis Criscuolo, Hans-Jurgen Busse, Peter Kampfer, Jean-Francois Bernardet, Dominique Clermont, Olivier Chesneau
Summary: Analysis of genome sequences from two strains of bacteria collected in Canada in the late 1970s led to the identification of a novel species in the Flavobacterium genus, named Flavobacterium bizetiae. Characteristics of F. bizetiae include yellow pigmentation, Gram-negative staining, non-spore forming, and gliding motility. It has the unique ability to utilize melibiose as the sole carbon source.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Microbiology
Dipen Pulami, Thorsten Schauss, Tobias Eisenberg, Jochen Blom, Oliver Schwengers, Jennifer K. Bender, Gottfried Wilharm, Peter Kaempfer, Stefanie P. Glaeser
Summary: The novel strain KPC-SM-21(T) isolated from a biogas plant in Germany represents a new species of the genus Acinetobacter, named Acinetobacter stercoris sp. nov. based on phylogenetic, genotypic, phenotypic, and chemotaxonomic data. The strain showed distinct clustering with Acinetobacter gerneri DSM 14967(T) in phylogenetic analysis, supported by average nucleotide identity values and whole-cell MALDI-TOF MS analysis.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY
(2021)
Article
Microbiology
Chandra Risdian, Wiebke Landwehr, Manfred Rohde, Peter Schumann, Richard L. Hahnke, Cathrin Sproeer, Boyke Bunk, Peter Kaempfer, Peter J. Schupp, Joachim Wink
Summary: A novel actinobacterium, designated ASO4wet(T), isolated from deep-sea sponge in the North Atlantic Ocean, is identified as a new species Streptomyces bathyalis through polyphasic taxonomy. Analysis of its whole-genome sequence revealed characteristics distinct from known Streptomyces species.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY
(2021)
Article
Microbiology
Stefanie P. Glaeser, Christian Rueckert, Usama Ramadan Abdelmohsen, Anika Winkler, Jochen Blom, Alexander Goesmann, Jorn Kalinowski, Ute Hentschel, Hans-Juergen Busse, Peter Kaempfer
Summary: A novel Streptomyces species, Streptomyces dysideae sp. nov., was isolated from a marine sponge collected in Croatia, exhibiting distinct morphological and physiological characteristics compared to other related Streptomyces species.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Microbiology
Peter Kampfer, S. P. Glaeser, John A. McInroy, Dominique Clermont, Alexis Criscuolo, Hans-Jurgen Busse
Summary: The bacterial isolate Wesi-4(T) from charcoal in 2012 was identified as a novel species in the genus Pseudomonas, named Pseudomonas carbonaria sp. nov., based on detailed polyphasic taxonomic analysis.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Ecology
Stefanie P. Glaeser, Liliana M. R. Silva, Rui Prieto, Monica A. Silva, Angel Franco, Peter Kampfer, Carlos Hermosilla, Anja Taubert, Tobias Eisenberg
Summary: The intestinal microbiomes of large baleen whales and toothed whales show significant differences at the family and genus levels, while similarities were observed at the phylum level. The most abundant phyla found were Firmicutes, Bacteroidetes, Proteobacteria, Tenericutes, and Spirochaeta.
Article
Multidisciplinary Sciences
Neoklis Apostolopoulos, Stefanie P. Glaeser, Ruchi Bagwe, Stefan Janssen, Ursula Mayer, Christa Ewers, Peter Kaempfer, Reto Neiger, Nina Thom
Summary: The study examined the bacterial microbiota of the skin and ear canals of healthy non-allergic and allergic German shepherd dogs, revealing differences in species richness and community composition between allergic and non-allergic dogs. The microbiome composition was most impacted by the household the dogs came from, followed by sex, host health status, and body site.
Article
Microbiology
Shadi Khodamoradi, Richard L. Hahnke, Yvonne Mast, Peter Schumann, Peter Kaempfer, Michael Steinert, Christian Rueckert, Frank Surup, Manfred Rohde, Joachim Wink
Summary: Strain M2(T) was isolated from the beach of Cuxhaven, Wadden Sea, Germany, producing litoralimycin and sulfomycin-type thiopeptides. It belongs to the genus Streptomonospora and represents a novel species, Streptomonospora litoralis sp. nov., based on phylogenetic and chemotaxonomic studies.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY
(2021)
Article
Microbiology
Hans-Juergen Busse, Peter Kaempfer, Michael Peter Szostak, Joachim Spergser
Summary: A novel bacterial species in the genus Luteolibacter, named Luteolibacter ambystomatis, was isolated from the skin of an Anderson's salamander. Through phylogenetic, genomic, physiological, and chemotaxonomic analysis, it was determined that strain 32A(T) represents a distinct species within the genus.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Microbiology
Peter Kaempfer, John A. McInroy, Dominique Clermont, Meina Neumann-Schaal, Alexis Criscuolo, Hans-Jurgen Busse, Stefanie P. Glaeser
Summary: A novel Leucobacter species, named Leucobacter soli sp. nov., has been identified from a soil sample in Malvern, AL, USA. Through ANI and dDDH analyses, as well as physiological and biochemical tests, the strain IMT-300(T) has been distinguished from closely related Leucobacter species, representing a unique taxonomic entity in the genus Leucobacter.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Microbiology
Peter Kaempfer, Hans-Juergen Busse, John A. McInroy, Dominique Clermont, Alexis Criscuolo, Stefanie P. Glaeser
Summary: A new bacterial strain, JJ-447(T), isolated from the rhizosphere of Zea mays, was identified as a novel species of the genus Paenibacillus, named Paenibacillus allorhizosphaerae sp. nov. The taxonomic assignment was confirmed through 16S rRNA gene sequence similarity comparisons, DNA-DNA hybridization, average nucleotide identity, and lipid analysis.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Juan F. Gago, Tomeu Viver, Mercedes Urdiain, Silvia Pastor, Peter Kaempfer, Pedro A. Robledo, Elaine Ferreira, Ramon Rossello-Mora
Summary: This study isolated over 140 strains from groundwater with thermal anomalies, and selected two strains for their taxonomic novelty and potential biotechnological relevance in the cosmetic industry. These strains represented a new species of the genus Hydrotalea, with ecological relevance demonstrated by denitrification, CRISPR-Cas system diversity, heavy metal resistance, and wide geographical distribution.
SYSTEMATIC AND APPLIED MICROBIOLOGY
(2021)
Article
Microbiology
Yina Cifuentes, Andreas Vilcinskas, Peter Kampfer, Stefanie P. Glaeser
Summary: Hermetia illucens larvae, also known as black soldier fly larvae (BSFL), are efficient in converting organic waste into high-quality biomass. This study explored the role of gut microbes in this process by culturing members of the core gut microbiota. Two cultivation strategies were employed, dilution-to-extinction cultivation and direct plating, resulting in the isolation of a diverse range of bacterial strains. Phylogenetic analysis identified predominant genera, such as Providencia, Proteus, Morganella, Enterococcus, Bacillus, and members of the family Enterobacteriaceae, which have been previously associated with the BSFL gut microbiota. Genomic fingerprinting provided insights into the genetic diversity of the cultured bacteria that could not be obtained solely through 16S rRNA gene sequencing.
ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY
(2022)
Article
Microbiology
Peter Kaempfer, Stefanie P. Glaeser, Hans-Juergen Busse, John A. McInroy, Dominique Clermont, Alexis Criscuolo
Summary: A novel bacterium belonging to the genus Pseudoneobacillus was isolated from the rhizosphere of maize roots, showing similarities to Neobacillus species but with distinct differences. Therefore, we propose the name Pseudoneobacillus rhizosphaerae gen. nov., sp. nov.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Microbiology
Hans-Juergen Busse, Peter Kaempfer, Michael P. Szostak, Joachim Spergser
Summary: In this study, a new bacterial strain was isolated from the cloaca of a giant Asian pond turtle and was named Ottowia testudinis sp. nov. It showed low similarity to established Ottowia species, indicating that it represents a novel species within the genus.
INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY
(2022)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)
