Article
Chemistry, Analytical
Ajith Mohan Arjun, Neermunda Shabana, Menon Ankitha, P. Abdul Rasheed
Summary: The study developed a novel composite of Nb2CTX MXene and Prussian blue (PB) to modify carbon cloth (CC) for the electrochemical detection of hydrogen peroxide (H2O2). The modified CC showed uniform coverage of PB on the Nb2CTX surface, and the deposition time of 480 s was found to be optimal for better sensing characteristics. The Nb2CTX/PB480 modified CC exhibited linear detection of H2O2 from 1 μM to 10 μM and from 10 μM to 100 μM, with a limit of detection of 200 nM. The sensor also demonstrated good selectivity to H2O2 in the presence of interfering molecules and exhibited good storage stability.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Xiaoli Liu, Xinjin Zhang, Jianbin Zheng
Summary: Hybrid nanomaterials of AuNPs-Prussian blue-Graphene oxide were successfully prepared using a one-pot strategy and used to construct an efficient H2O2 electrochemical sensor. Characterizations revealed successful loading of gold nanoparticles, leading to superior sensor performance and stability.
MICROCHEMICAL JOURNAL
(2021)
Article
Biochemistry & Molecular Biology
Long Yan, Kunpeng Miao, Pengcheng Ma, Xiaoyan Ma, Ran Bi, Fang Chen
Summary: The highly sensitive H2O2 biosensor was successfully constructed by forming coral-like gold micro/nanostructures onto carbon cloth followed by PB electrochemical deposition. Furthermore, a glucose biosensor GOx(EA)@PB/Au/CC with high sensitivity, selectivity, reproducibility, and stability was established using the cross-linking enzyme aggregates method. The proposed biosensor was successfully applied for glucose determination in real human serum samples, demonstrating its practicality.
BIOELECTROCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Adaly Garcia, Kinsley Wang, Fatima Bedier, Miriam Benavides, Zijian Wan, Shaopeng Wang, Yixian Wang
Summary: Research on the electrochemical activity of Prussian blue nanoparticles showed that plasmonic electrochemical microscopy can be used to detect and sense hydrogen peroxide at the single nanoparticle level.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Xiaogang Mei, Siyuan Lu, Ying Chen
Summary: The influence of deposition time on the microstructure and electrochemical properties of SMG/PB-modified electrodes was investigated. The results showed that the optimized deposition time of 240 s resulted in SMG/PB-modified electrodes with the widest linear range and best stability.
Review
Chemistry, Inorganic & Nuclear
Xiaqing Dong, Xuanming Liu, Min Cheng, Danlian Huang, Gaoxia Zhang, Wenjun Wang, Li Du, Guangfu Wang, Hongda Liu
Summary: This article provides an in-depth overview of the environmental remediation of Prussian blue (PB) and its analogues (PBAs) in Fenton-like advanced oxidation processes. It summarizes the common synthetic strategies for PB/PBAs-based materials and discusses their applications in the removal of organic matter and purification of wastewater. The review also highlights their catalytic mechanisms and the identification of reactive oxygen species (ROS), and proposes unresolved challenges and future perspectives.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Luiza Izabela Jinga, Gianina Popescu-Pelin, Gabriel Socol, Sorin Mocanu, Madalina Tudose, Daniela C. Culita, Andrei Kuncser, Petre Ionita
Summary: In this study, gold nanoparticles were deposited on titanium dioxide nanoparticles and the material was found to effectively degrade methylene blue dye in the presence of hydrogen peroxide. Longer exposure time and higher oxidant content led to up to 90% degradation of the dye. The material showed promising reusability without loss of activity.
Article
Chemistry, Analytical
Sheida Esmail Tehrani, Long Quang Nguyen, Giulia Garelli, Bettina M. Jensen, Tautgirdas Ruzgas, Jenny Emneus, Stephan Sylvest Keller
Summary: A highly sensitive amperometric Prussian blue-based hydrogen peroxide sensor was developed using 3D pyrolytic carbon microelectrodes, enabling simultaneous highly reproducible Prussian blue modification on multiple carbon electrodes. The study investigated the effect of oxygen plasma pre-treatment and deposition time on Prussian blue electrodeposition, demonstrating high sensitivity comparable to flow injection systems and a detection limit of 0.16 μM with 3D pyrolytic carbon microelectrodes at stirred batch condition.
Article
Chemistry, Analytical
Laura Sakalauskiene, Benediktas Brasiunas, Anton Popov, Asta Kausaite-Minkstimiene, Almira Ramanaviciene
Summary: The development of a first-generation reagentless amperometric glucose biosensor based on the combination of AuNS, PB, and GOx has been achieved, enabling convenient and intuitive glucose detection. The biosensor exhibits a wide linear range, good repeatability, and high selectivity.
Article
Chemistry, Analytical
Darya Vokhmyanina, Elena Daboss, Olesya Sharapova, Mariia Mogilnikova, Arkady Karyakin
Summary: Hydrogen peroxide sensors were made through a single printing step with carbon ink containing catalytically synthesized Prussian blue nanoparticles. The resulting bulk-modified sensors had a wider linear calibration range and a lower detection limit compared to surface-modified sensors, due to decreased noise and increased signal-to-noise ratio. The glucose and lactate biosensors based on these sensors showed similar or higher sensitivities compared to surface-modified biosensors.
Article
Energy & Fuels
Jinyou Fei, Siqi Li, Miao Han, Yugang Su, Hongsheng Jia
Summary: The Prussian blue analogue Co3[Co(CN)6]2 (CoCo-PBA) nanoparticles with three-dimensional cubic structure and uniform size are prepared using the precipitation method. The porous Co9S8/N-doped carbon (Co9S8-NC) nanostructure is fabricated via heat treatment and sulfidation processes using CoCo-PBA as the precursor. The porous Co9S8-NC is mixed with RGO by ball milling to enhance the conductivity and electrocatalytic activity. During the electrochemical hydrogen storage test, the porous Co9S8-NC exhibits higher discharge capacity than conventional Co9S8. The conductivity of Co9S8 is enhanced due to the existence of N-doped carbon. The special porous structure and large specific surface area derived from CoCo-PBA provide more electrochemical active sites. Moreover, the electrochemical properties further improve after RGO modification because of the outstanding characteristics of RGO. A highest discharge capacity of 640.8 mAh/g is obtained for the Co9S8-NC/RGO electrode. Additionally, the cycling stability, HRD and kinetic properties are also enhanced with the addition of RGO. As a consequence, Co9S8-NC/RGO can be regarded as a promising material for electrochemical hydrogen storage.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Electrochemistry
Sukanya Jankhunthod, Chochanon Moonla, Athis Watwiangkham, Suwit Suthirakun, Theeranun Siritanon, Suttipong Wannapaiboon, Kamonwad Ngamchuea
Summary: Copper hexacyanoferrate (CuHCF) shows excellent electrocatalytic activity for H2O2 reduction, making it a suitable electrode material for H2O2 sensors and energy storage devices. Different samples of CuHCF were synthesized and tested, with the CuSO4 and K3Fe(CN)6 co-precipitated at a 2:1 ratio at room temperature showing the highest electroactivity and cycling stability.
ELECTROCHIMICA ACTA
(2021)
Article
Nanoscience & Nanotechnology
Robert Barber, James Davis, Pagona Papakonstantinou
Summary: Developing a noninvasive skin peroxide monitoring technology using laser-induced graphene (LIG) and Prussian blue (PB)-chitosan (CS) network for stable and sensitive detection of H2O2 in human eccrine perspiration. The sensor operates at a low potential in unmodified human eccrine perspiration, ensuring high specificity and stability.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Seema Chauhan, Chhaya Sharma
Summary: An electrochemical sensor based on PBNCs/AuNPs/RGO ternary nanocomposite was developed, which exhibited high catalytic activity for H2O2 sensing. The modified electrode showed high sensitivity and low detection limit for H2O2, along with good stability and selectivity.
Article
Nanoscience & Nanotechnology
Qianqian Wang, Xuemin Zhang, Xueying Chai, Tieqiang Wang, Tianlong Cao, Yunong Li, Liying Zhang, Fuqiang Fan, Yu Fu, Wei Qi
Summary: Precise and real-time detection of hydrogen peroxide (H2O2) is achieved through the in situ preparation of an electrocatalytic active film with Au nanoparticles (Au NPs) embedded in a metal-organic framework (UiO-66) film on the surface of an electrode. By controlling the electrodeposition conditions, the size of Au nanoparticles and electrochemical activity of the film can be manipulated.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Yonghwang Ha, Dhiraj P. Murale, Changsuk Yun, Sudesh T. Manjare, Hyungjun Kim, Juhyoun Kwak, Yoon Sup Leea, David G. Churchill
CHEMICAL COMMUNICATIONS
(2015)
Article
Chemistry, Multidisciplinary
Hosuk Kang, Seongpil Hwang, Juhyoun Kwak
Article
Electrochemistry
Seungjin Park, Jun Hui Park, Seongpil Hwang, Juhyoun Kwak
ELECTROCHEMISTRY COMMUNICATIONS
(2016)
Article
Chemistry, Multidisciplinary
Changsuk Yun, Seongpil Hwang, Juhyoun Kwak
Article
Chemistry, Multidisciplinary
Mijeong Kang, Seungmoon Jung, Huanan Zhang, Taejoon Kang, Hosuk Kang, Youngdong Yoo, Jin-Pyo Hong, Jae-Pyoung Ahn, Juhyoun Kwak, Daejong Jeon, Nicholas A. Kotov, Bongsoo Kim
Article
Chemistry, Analytical
Kyungsoon Park, Seong Jung Kwon, Juhyoun Kwak
Article
Electrochemistry
Jun Hui Park, Seongpil Hwang, Byung-Kwon Kim, Juhyoun Kwak
ELECTROCHEMISTRY COMMUNICATIONS
(2013)
Article
Chemistry, Inorganic & Nuclear
Olga G. Tsay, Byung-Kwon Kim, Tuong Loan Luu, Juhyoun Kwak, David G. Churchill
INORGANIC CHEMISTRY
(2013)
Article
Nanoscience & Nanotechnology
Hye Young Jung, Jun Hui Park, Seongpil Hwang, Juhyoun Kwak
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
(2013)
Article
Chemistry, Analytical
Byung-Kwon Kim, Ji Young Lee, Jun Hui Park, Juhyoun Kwak
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2013)
Article
Polymer Science
Jinhee Lee, Jaewon Heo, Changjun Park, Byung-Kwon Kim, Juhyoun Kwak, Myungeun Seo, Sang Youl Kim
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
(2014)
Article
Biochemistry & Molecular Biology
Sunae Jo, Sung Min Kang, Su A. Park, Wan Doo Kim, Juhyoun Kwak, Haeshin Lee
MACROMOLECULAR BIOSCIENCE
(2013)
Article
Chemistry, Multidisciplinary
Changsuk Yun, Seung-Hoon Lee, Jehyeok Ryu, Kyungsoon Park, Jae-Won Jang, Juhyoun Kwak, Seongpil Hwang
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2018)
Article
Chemistry, Multidisciplinary
Changsuk Yun, Hosuk Kang, Juhyoun Kwak, Seongpil Hwang
Article
Nanoscience & Nanotechnology
Seungjin Park, Jun Hui Park, Seongpil Hwang, Juhyoun Kwak
ACS APPLIED MATERIALS & INTERFACES
(2017)
Article
Biophysics
Reza Khodadadi, Manouchehr Eghbal, Hamideh Ofoghi, Alireza Balaei, Ali Tamayol, Karen Abrinia, Amir Sanati-Nezhad, Mohamadmahdi Samandari
Summary: This paper introduces an integrated portable centrifugal microfluidic system that automates cell and fluid manipulation for complete blood counting (CBC) analysis at the point-of-care (POC). The system utilizes a specially designed microfluidic disc for cell separation, solution metering and mixing, and cell counting, and is equipped with a custom script for automated quantification of cells. The proposed method shows a strong correlation with the gold standard hematology analyzer for various blood parameters. The portable system offers simplicity, affordability, and low power consumption, making it a potential solution for improving healthcare delivery in resource-limited settings and remote areas.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Nabil H. Bhuiyan, Joon S. Shim
Summary: Developing herd immunity is crucial for changing the course of the COVID-19 pandemic. An AI-driven point-of-care testing platform has been proposed for analyzing the body's response to SARS-CoV-2, and it has been successfully used for quantifying viral proteins and antibodies in blood samples. A data-receptive web-based dashboard system has also been developed for real-time analysis of herd immunity progress.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Alexiane Godain, Timothy M. Vogel, Pascal Fongarland, Naoufel Haddour
Summary: This study provides comprehensive insights into the intricate relationship between shear stress and electroactive biofilms in microbial fuel cells, highlighting the pivotal role of shear stress in influencing the growth kinetics, electrical performance, and physical structure of the biofilms. The study also emphasizes the complexities of extracellular electron transfer mechanisms and the need for complementary metaproteomic analyses.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Linjie Wang, Yixin Chen, Yang Ji, Shujun Zheng, Fei Wang, Caolong Li
Summary: A paper-based biosensor incorporating surface-enhanced Raman spectroscopy (SERS) and colorimetric detection has been developed for efficient quantification of intracellular glutathione (GSH). The biosensor exhibits excellent selectivity, stability, and precision, with low detection limits in both SERS and colorimetric modes. It has been successfully utilized for intracellular GSH detection and validated against a commercial GSH assay kit.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Quan Zhou, Jing Wang, Zhen Zhang, Alain Wuethrich, Richard J. Lobb, Matt Trau
Summary: This study presents a biosensor for sensitive detection of EMT-associated biomarkers on extracellular vesicles (EVs) surfaces during targeted therapy. Through longitudinal monitoring of patients, the biosensor shows its ability to identify the EMT-like phenotype switching on circulating EVs during the development of resistance.
BIOSENSORS & BIOELECTRONICS
(2024)
Review
Biophysics
Pratika Rai, Sabrina N. Hoba, Celine Buchmann, Robert J. Subirana-Slotos, Christian Kersten, Tanja Schirmeister, Kristina Endres, Bernd Bufe, Alexey Tarasov
Summary: Proteases have been proposed as potential biomarkers for various pathological conditions. The development of protease biosensors offers a more efficient way to investigate dysregulated proteases. This review article presents different optical and electrochemical detection methods for designing biosensors for all major protease families.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Chengxin Liu, Xu Shen, Li Yan, Runlian Qu, Yue Wang, Yaqin He, Zixuan Zhan, Piaopiao Chen, Feng Lin
Summary: In this study, a homogeneous rapid electrochemical aptasensor was developed to quantitatively detect CTCs in lung cancer patients. The aptasensor utilized a DNA nanosphere structure and a complementary aptamer to specifically detect mucin 1 as a marker for CTCs. The assay exhibited high specificity and sensitivity, and the results were consistent with other detection methods.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Danni Xue, Xing Dai, Jialong Zhao, Jiayao Zhang, Huan Liu, Kui Liu, Tao Xu, Chenjie Gu, Xingfei Zhou, Tao Jiang
Summary: In this study, a dual-enhancement SERS substrate based on Ti3C2TX and Ag nanocubes was fabricated for precise quantification of ritonavir and ibrutinib in serum. The formation of numerous electromagnetic hotspots between Ag nanocubes facilitated effective photo-induced charge transfer. The composite substrate showed excellent sensitivity, achieving low detection limits and high recoveries, making it promising for monitoring and identification of clinical blood drug concentration.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Tenghua Zhang, Zihui Xie, Xiaohe Zheng, Yuxin Liang, Yao Lu, Hankang Zhong, Feiyang Qian, Yuqing Zhu, Ruiting Sun, Yan Sheng, Jiaming Hu
Summary: This study reports a technology based on cationic lipid-polymer hybrid nanoparticles for efficient extracellular vesicle (EV) enrichment and in-situ detection of internal microRNAs. The technology demonstrates high EV enrichment efficiency and sensitive internal RNA detection, making it potentially useful for early pancreatic cancer diagnosis.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Wenjie Dai, Gaoxu Chen, Xiaoyan Wang, Shujun Zhen, Chengzhi Huang, Lei Zhan, Yuanfang Li
Summary: In this study, a novel metal organic gel (MOG) with dual electrochemiluminescence (ECL) properties was prepared by simple mixing. The MOG exhibited strong and stable anodic and cathodic ECL signals. By utilizing this MOG, an ECL resonance energy transfer (ECL-RET) biosensor was constructed for ultrasensitive detection of a specific gene. The study developed a straightforward technique for obtaining a single luminescent material with dual signals and expanded the analytical application of MOGs in the realm of ECL.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Lais Canniatti Brazaca, Amanda Hikari Imamura, Rodrigo Vieira Blasques, Jessica Rocha Camargo, Bruno Campos Janegitz, Emanuel Carrilho
Summary: The use of microfluidic paper-based analytical devices (muPADs) for medical diagnosis is a growing trend due to their low cost, easy use, simple manufacturing, and potential for application in low-resource settings. This review focuses on the advances in muPADs for medical diagnostics, discussing their use in detecting various biomarkers in common human biofluids. The challenges of biomarker detection in each sample are examined, along with innovative techniques to overcome these limitations. The commercialization difficulties of muPADs are also considered, along with future trends such as wearable devices and integrated platforms.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Minghong Jian, Xudong Sun, Hua Zhang, Xiaotong Li, Shasha Li, Zhenxin Wang
Summary: Matrix metalloproteinases (MMPs) are attractive biomarkers for cancer diagnosis and treatment, but their low abundance in biological samples, especially in the early stages of tumors, makes it challenging to precisely analyze MMP activities. In this study, a peptide microarray-based metal-enhanced fluorescence assay (PMMEFA) is proposed as a sensitive and specific method to simultaneously detect MMP-1, -2, -3, -7, -9, and -13 activities. The PMMEFA showed excellent sensitivity and was capable of detecting MMP activities in various matrices.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Kyung Ho Kim, Eunsu Ryu, Zinah Hilal Khaleel, Sung Eun Seo, Lina Kim, Yong Ho Kim, Hyun Gyu Park, Oh Seok Kwon
Summary: We have developed a novel strategy for discriminative detection of SARS-CoV-2 variants using the plasmonic photothermal effect of gold nanofilms and digital polymerase chain reaction (dPCR) technology. With this method, we were able to detect the delta and omicron variants with high sensitivity within 25 minutes from COVID-19 patients' clinical samples, making it a rapid and accurate point-of-care testing tool.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Zepeng Kang, Yuanming Wang, Haiyan Song, Xueli Wang, Job Zhang, Zhiguang Zhu
Summary: By designing a wearable and flexible lactic-acid/O2 EBFC with an air-breathing biocathode, the limitations of biocathode are effectively solved. The optimal performance conditions are determined through experiments, and the EBFC is successfully applied to power a low-power device.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Biophysics
Huayun Chen, Zhiheng You, Yuhui Hong, Xiao Wang, Mingming Zhao, Yushi Luan, Yibin Ying, Yixian Wang
Summary: This study developed a colorimetric sensor array using gas-responsive two-dimensional metal-organic framework (MOF) composites for highly sensitive detection of volatile organic compounds (VOCs). The dye/Zn-2(bim)(4) composites-based sensor arrays showed enhanced sensitivity and anti-interference properties. The findings demonstrate the potential use of dye/Zn-2(bim)(4) sensor arrays for early perception of plant diseases.
BIOSENSORS & BIOELECTRONICS
(2024)