Mitochondrial dysfunction in insulin resistance: differential contributions of chronic insulin and saturated fatty acid exposure in muscle cells

Increasing Dietary Fat Elicits Similar Changes in Fat Oxidation and Markers of Muscle Oxidative Capacity in Lean and Obese Humans

(2012) Audrey Bergouignan et al.   PLoS One

Protection from Palmitate-Induced Mitochondrial DNA Damage Prevents from Mitochondrial Oxidative Stress, Mitochondrial Dysfunction, Apoptosis, and Impaired Insulin Signaling in Rat L6 Skeletal Muscle Cells

(2011) Larysa V. Yuzefovych et al.   ENDOCRINOLOGY

Hydrogen Peroxide Production Is Not Primarily Increased in Human Myotubes Established from Type 2 Diabetic Subjects

(2011) A. D. Minet et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress

(2010) Larysa Yuzefovych et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

ATP synthesis is impaired in isolated mitochondria from myotubes established from type 2 diabetic subjects

(2010) Ariane D. Minet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased Reactive Oxygen Species Production and Lower Abundance of Complex I Subunits and Carnitine Palmitoyltransferase 1B Protein Despite Normal Mitochondrial Respiration in Insulin-Resistant Human Skeletal Muscle

(2010) N. Lefort et al.   DIABETES

Short Report: Tissue-specific Expression Profiles of the Uncoupling Protein Family in Normal Control Mice and Genetically ob/ob Mice

(2010) Chun-Mei Zhang et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

A Novel Intronic Peroxisome Proliferator-activated Receptor γ Enhancer in the Uncoupling Protein (UCP) 3 Gene as a Regulator of Both UCP2 and -3 Expression in Adipocytes

(2010) Anne Bugge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation

(2010) C.E. Ash et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Diacylglycerol-mediated insulin resistance

(2010) Derek M Erion et al.   NATURE MEDICINE

The Randle cycle revisited: a new head for an old hat

(2009) Louis Hue et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reduced TCA flux in diabetic myotubes: A governing influence on the diabetic phenotype?

(2009) Michael Gaster   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Proteomics Analysis of Human Skeletal Muscle Reveals Novel Abnormalities in Obesity and Type 2 Diabetes

(2009) H. Hwang et al.   DIABETES

Nutritional and hormonal regulation of uncoupling protein 2

(2009) Tomo Yonezawa et al.   IUBMB LIFE

Insulin stimulates Akt translocation to mitochondria: Implications on dysregulation of mitochondrial oxidative phosphorylation in diabetic myocardium

(2009) Jia-Ying Yang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

(2008) E. Phielix et al.   DIABETES

Transcriptional profiling of myotubes from patients with type 2 diabetes: no evidence for a primary defect in oxidative phosphorylation genes

(2008) C. M. Frederiksen et al.   DIABETOLOGIA

PGC-1α Integrates Insulin Signaling, Mitochondrial Regulation, and Bioenergetic Function in Skeletal Muscle

(2008) Ines Pagel-Langenickel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transcriptional co-activator peroxisome proliferator-activated receptor (PPAR)γ co-activator-1β is involved in the regulation of glucose-stimulated insulin secretion in INS-1E cells

(2008) Hannes Oberkofler et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Mitochondrial Fusion Is Increased by the Nuclear Coactivator PGC-1β

(2008) Marc Liesa et al.   PLoS One