期刊
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
卷 78, 期 11, 页码 1939-1942出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09168451.2014.943647
关键词
alpha-lipoic acid; invasion; migration; beta 1-integrin; bladder cancer cells
类别
资金
- [20580137]
Here, we show that cell surface beta 1-integrin expression, cell adhesion to fibronectin, migration, and invasion were all significantly inhibited by alpha-lipoic acid. These effects were not observed when cells were treated with dihydrolipoic acid or caprylic acid. These data reveal that the 1,2-dithiolane structure plays an important role in the action of alpha-lipoic acid.
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