Article
Biotechnology & Applied Microbiology
Tomas Ortiz-Rodriguez, Fernanda Mendoza-Acosta, Sheila A. Martinez-Zavala, Ruben Salcedo-Hernandez, Luz E. Casados-Vazquez, Dennis K. Bideshi, Jose E. Barboza-Corona
Summary: This study demonstrates that the bacteriocin thurincin H, produced by Bacillus thuringiensis, has antibacterial activity but lacks hemolytic properties. These findings are important for the potential use of thurincin H as an antibacterial peptide in medicine and food products.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Review
Pharmacology & Pharmacy
Margarita O. Shleeva, Daria A. Kondratieva, Arseny S. Kaprelyants
Summary: Bacillus licheniformis produces a variety of antimicrobial substances, including bacteriocins, non-ribosomally synthesized peptides and cyclic lipopeptides, and exopolysaccharides. These substances exhibit lytic activity against different types of bacteria, fungi, and amoeba cells through various mechanisms such as membrane interaction, pore-forming, and cell wall inhibition. Some of these substances have been studied in vivo and found practical applications in medicine and veterinary. B. licheniformis has the potential to be used as a natural vehicle for antibiotic substances to combat various pathogens.
Article
Food Science & Technology
Yi-Zhou Xiang, Xin-Yue Li, Hai-Long Zheng, Jun-Yuan Chen, Lian-Bing Lin, Qi-Lin Zhang
Summary: The novel bacteriocin JS17 obtained from Bacillus subtilis isolated from blueberry ferments showed extensive antibacterial activity, heat tolerance, and high stability over pH 2-10, making it a potential food bio-preservative. Additionally, JS17 exhibited lower minimum inhibitory and bactericidal concentrations against Escherichia coli compared to most known bacteriocins.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Food Science & Technology
Zhaohui Wei, Chengjun Shan, Lixia Zhang, Da'e Ge, Ying Wang, Xiudong Xia, Xiaoli Liu, Jianzhong Zhou
Summary: Subtilin JS-4 is a highly effective antibacterial peptide against the foodborne pathogen Listeria monocytogenes, showing good thermal and pH stability and a broad antimicrobial spectrum against Gram-positive bacteria. Its antibacterial mechanism involves increasing cell membrane permeability, triggering ion leakage and pore formation, damaging cell membrane integrity, and altering cell morphology and intracellular organization.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Jing Zhang, Manyu Liang, Lijuan Wu, Yanhong Yang, Yingjie Sun, Qin Wang, Xiaowei Gao
Summary: This study developed a simple and cost-effective method to digest feathers using Bacillus licheniformis WHU, yielding a hydrolysate that can be directly used as a bioactive nutrient resource. In addition, supplementation with feather hydrolysate had positive effects on intestinal health, immune function, and microbial composition in mice.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Microbiology
Penka Petrova, Alexander Arsov, Ivan Ivanov, Lidia Tsigoriyna, Kaloyan Petrov
Summary: Bacillus licheniformis 24 produces EPSs with different sugar compositions based on the substrate, and higher yields were obtained in batch and fed-batch processes in a fermenter at specific conditions. EPS2 exhibited stronger antioxidant activity than EPS1, and both EPSs were only produced during the exponential growth phase.
Article
Engineering, Environmental
Maryam Khalili Samani, Zahra Noormohammadi, Mohammad Reza Fazeli, Nasrin Samadi
Summary: This study investigated the antibacterial activity of Iranian honey from different regions, identifying Bacillus subtilis SB1 from Sabalan honey as a potent source of antibacterial compounds. Optimal conditions for bacteriocin production were found to be a yeast extract-based medium at 34 degrees C with near neutral pH. Production of antibacterial compounds in bioreactor was found to be more rapid than in shake flask.
JOURNAL OF ENVIRONMENTAL HEALTH SCIENCE AND ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Lidiya C. Johny, P. Suresh
Summary: Bacillus velezensis FTL7, isolated from a marine sediment sample in South India, demonstrated potent antimicrobial peptide production. It exhibited potential antimicrobial activity against various foodborne pathogenic bacteria and its genomic analysis revealed the presence of genes responsible for antimicrobial substance synthesis.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
(2022)
Review
Biotechnology & Applied Microbiology
Andrea Muras, Manuel Romero, Celia Mayer, Ana Otero
Summary: Bacillus licheniformis is a Gram positive spore-forming bacterial species with high biotechnological potential, used for producing bioactive compounds and bioproducts in various fields. Its applications include probiotics, bioflocculation, biofuel production, and bioremediation among others, but safety concerns exist due to potential transfer of antibiotic resistance genes. Developing a standardized protocol to describe novel strains is crucial for evaluating the biotechnological potential of this species.
CRITICAL REVIEWS IN BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Yuan Yuan, Demin Kong, Jing Wu, Lingqia Su
Summary: In this study, the optimal promoter SpoVG and signal peptide YqxI were obtained and the chitinase BlChiA from Bacillus licheniformis was successfully recombinantly expressed in Bacillus subtilis. Mutant libraries were constructed and mutants with enhanced activities were obtained. The mutant E336K/A472T exhibited the highest expression level of BlChiA in Bacillus subtilis and also showed greater acid adaptability. These findings provide a foundation for further exploration of the enzyme's function and industrial application.
PROCESS BIOCHEMISTRY
(2023)
Article
Chemistry, Organic
Karen D. Milewska, Lara R. Malins
Summary: This paper describes the preparation of cross-linked amino acid alpha-thioether building blocks and their stability towards conventional solid-phase peptide synthesis, overcoming challenges with linkage lability by developing a late-stage, on-resin approach to alpha-thioethers, providing important proof-of-principle for sactipeptide synthesis.
Article
Multidisciplinary Sciences
Lama Shamseddine, Clarisse Roblin, Iris Veyrier, Christian Basset, Lisa De Macedo, Anne Boyeldieu, Marc Maresca, Cendrine Nicoletti, Gael Brasseur, Sylvie Kieffer-Jaquinod, Elise Courvoisier-Dezord, Agnes Amouric, Philippe Carpentier, Nathalie Campo, Mathieu Berge, Patrice Polard, Josette Perrier, Victor Duarte, Mickael Lafond
Summary: In the context where discovering new molecules to combat antibiotic resistance is important for public health, ribosomally synthesized and post-translationally modified peptides, known as sactipeptides, show promise as an alternative. In this study, the gut symbiont Ruminococcus gnavus E1 was found to produce five sactipeptides, named Ruminococcins C1 to C5 (RumC1-C5), along with two maturases. The antibacterial activities of the mature forms of RumC2-5 were evaluated and variations in efficacy and synergy with conventional antibiotics were observed.
Article
Biochemistry & Molecular Biology
Amarila Malik, Elita Yuliantie, Nisa Yulianti Suprahman, Theresa Linardi, Angelina Wening Widiyanti, Jeanita Haldy, Catherine Tjia, Hiroshi Takagi
Summary: The study successfully constructed recombinant bacteriocin genes and obtained pure recombinant bacteriocins on a large scale, showing weak but confirmed antibacterial activity against gram-positive bacteria.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2021)
Article
Microbiology
Carol M. Romo-Barrera, Laura E. Castrillon-Rivera, Alejandro Palma-Ramos, Jorge I. Castaneda-Sanchez, Julieta Luna-Herrera
Summary: The research found that macrophages have a certain resistance to infection by probiotics such as Bacillus, using METs for self-clearance. Additionally, Bacillus can induce macrophages to release extracellular DNA, thereby inhibiting the growth of Staphylococcus aureus.
Article
Biochemistry & Molecular Biology
Alexander Arsov, Kaloyan Petrov, Penka Petrova
Summary: The study aimed to enhance the natural cellulase activity of Bacillus licheniformis and B. velezensis by cloning and heterologous expression of cel8A and cel48S genes from Acetivibrio thermocellus. The results demonstrate the potential for genetic complementation to significantly increase cellulase activity in bacilli.
Meeting Abstract
Gastroenterology & Hepatology
Naresh Bhat, Pradeep Kakkadasam Ramaswamy, Amit Yelsangikar, Kayalvizhi Nagarajan, Anupama Nagar
Meeting Abstract
Gastroenterology & Hepatology
Naresh Bhat, Pradeep Kakkadasam Ramaswamy, Amit Yelsangikar, Kayalvizhi Nagarajan, Anupama Nagar
Article
Food Science & Technology
Nagarajan Kayalvizhi, Neelamegam Rameshkumar, Paramasamy Gunasekaran
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2016)
Meeting Abstract
Gastroenterology & Hepatology
Kayalvizhi Nagarajan, Pradeep Kakkadasam Ramaswamy, Amit Yelsangikar, Anupama Nagar, Naresh Bhat
GASTROINTESTINAL ENDOSCOPY
(2017)
Article
Genetics & Heredity
Murugan Mukilan, David Mary Rajathei, Edwin Jeyaraj, Nagarajan Kayalvizhi, Koilmani Emmanuvel Rajan
Article
Biochemistry & Molecular Biology
Thangarasu Arumugam, Selvam Dhanam, Neelamegam Rameshkumar, Muthukalingan Krishnan, Nagarajan Kayalvizhi
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS
(2019)
Article
Oncology
Seemaisamy Revathi, Faruck L. Hakkim, Neelamegam R. Kumar, Hamid A. Bakshi, Luay Rashan, Mohammed Ai-Buloshi, Sidgi S. A. A. Hasson, Muthukalingan Krishnan, Farideh Javid, Kayalvizhi Nagarajan
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
(2018)
Article
Biochemistry & Molecular Biology
Pratheep Thangaraj, Ramesh Kumar Neelamegam, Kayalvizhi Nagarajan, Krishnan Muthukalingan
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
R. K. Govindarajan, Krishnamurthy Mathivanan, Neelamegam Rameshkumar, Douglas J. H. Shyu, Muthukalingan Krishnan, Nagarajan Kayalvizhi
PROCESS BIOCHEMISTRY
(2019)
Article
Pharmacology & Pharmacy
Revathi Seemaisamy, Lukmanul Hakkim Faruck, Sampath Gattu, Rameshkumar Neelamegam, Hamid A. Bakshi, Luay Rashan, Mohammed Al-Buloshi, Sidgi Syed Anwar Abdo Hasson, Kayalvizhi Nagaraj
INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH
(2019)
Proceedings Paper
Engineering, Biomedical
M. Lokharan, Lokesh K. C. Kumar, Harish Kumar, N. Kayalvizhi, R. Aryalekshmi
16TH INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING
(2017)
Proceedings Paper
Engineering, Biomedical
Theertha Abhay, N. Kayalvizhi, Rolant J. Gini
16TH INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING
(2017)
Article
Biotechnology & Applied Microbiology
Seemaisamy Revathi, R. K. Govindarajan, Neelamegam Rameshkumar, Faruck Lukmanul Hakkim, Al-Buloshi Mohammed, Muthukalingan Krishnan, Nagarajan Kayalvizhi
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2017)
Article
Chemistry, Medicinal
K. Nagaraj, D. Narendar, V. Kishan
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2017)
Review
Biotechnology & Applied Microbiology
R. K. Govindarajan, Seemaisamy Revathi, Neelamegam Rameshkumar, Muthukalingan Krishnan, Nagarajan Kayalvizhi
BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY
(2016)
Article
Agricultural Engineering
Yinping Xiang, Meiying Jia, Rui Xu, Jialu Xu, Lele He, Haihao Peng, Weimin Sun, Dongbo Wang, Weiping Xiong, Zhaohui Yang
Summary: This study investigated the impact of the non-antibiotic pharmaceutical carbamazepine on antibiotic resistance genes (ARGs) during anaerobic digestion. The results showed that carbamazepine induced the enrichment of ARGs and increased the abundance of bacteria carrying these genes. It also facilitated microbial aggregation and intercellular communication, leading to an increased frequency of ARGs transmission. Moreover, carbamazepine promoted the acquisition of ARGs by pathogens and elevated their overall abundance.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Weixin Zhao, Tianyi Hu, Hao Ma, Dan Li, Qingliang Zhao, Junqiu Jiang, Liangliang Wei
Summary: This review summarizes the effects and potential mechanisms of biochar on microbial behavior in AD systems. The addition of biochar has been found to promote microbial colonization, alleviate stress, provide nutrients, and enhance enzyme activity. Future research directions include targeted design of biochar, in-depth study of microbial mechanisms, and improved models.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Christina Karmann, Anna Magrova, Pavel Jenicek, Jan Bartacek, Vojtech Kouba
Summary: This review assesses nitrogen removal technologies in reject water treatment, highlighting the differences in environmental impacts and economic benefits. Partial nitritation-anammox shows potential for economic benefits and positive environmental outcomes when operated and controlled properly.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Wei-Hao Huang, Ying-Ju Chang, Duu-Jong Lee
Summary: This study modified pinecone biochar with layered double hydroxide (LDH) to enhance its adsorption capacity for heavy metal and phosphate ions. The LDH-biochar showed significantly improved adsorption capacities for Pb2+ and phosphate, and a slight increase for Cu2+ and Co2+. The LDH layer enhanced the adsorption through various mechanisms.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Chao Song, Fanfan Cai, Shuang Yang, Ligong Wang, Guangqing Liu, Chang Chen
Summary: This paper developed a machine learning model to predict the biochemical methane potential during anaerobic digestion. Model analysis identified lignin content, organic loading, and nitrogen content as key attributes for methane production prediction. For feedstocks with high cellulose content, early methane production is lower but can be improved by prolonging digestion time. Moreover, lignin content exceeding a certain value significantly inhibits methane production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sang Min Lee, Ju Young Lee, Ji-Sook Hahn, Seung-Ho Baek
Summary: This study successfully developed an efficient platform strain using Yarrowia lipolytica for the bioconversion of renewable resources into adipic acid, achieving a remarkable increase in production level.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sefkan Kendir, Matthias Franzreb
Summary: This study presents a novel approach using magnetic separation to efficiently harvest freshwater microalgae, Chlorella vulgaris. By combining pH-induced calcium phosphate precipitation with cheap natural magnetite microparticles, harvesting efficiencies up to 98% were achieved in the model medium.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Ishaq Kariim, Ji-Yeon Park, Wajahat Waheed Kazmi, Hulda Swai, In-Gu Lee, Thomas Kivevele
Summary: The impact of reaction temperature, residence time, and ethanol: acetone on the energy compositions and yield enhancement of biocrudes was investigated. The results showed that under appropriate conditions, biocrudes with high energy and low oxygen content can be obtained, indicating a high potential for utilization.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xiyue Zhang, Xiyao Li, Liang Zhang, Yongzhen Peng
Summary: Intermittent aeration is an innovative approach to enhance nitrogen removal in low carbon-to-nitrogen ratio municipal sewage, providing an efficient strategy for the continuous plug-flow AOA process.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xu Yang, Mahmoud Mazarji, Mengtong Li, Aohua Li, Ronghua Li, Zengqiang Zhang, Junting Pan
Summary: This study investigated the impact of magnetite on the nitrogen cycle of pig manure biostabilisation. The addition of magnetite increased N2O emissions and decreased NH3 emissions during composting. It also increased the total nitrogen content but should be considered for its significant increase in N2O emissions in engineering practice.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Ty Shitanaka, Haylee Fujioka, Muzammil Khan, Manpreet Kaur, Zhi-Yan Du, Samir Kumar Khanal
Summary: The market value of microalgae has exponentially increased in the past two decades, thanks to their applications in various industries. However, the supply of high-value microalgal bioproducts is limited due to several factors, and strategies are being explored to overcome these limitations and improve microalgae production, thus increasing the availability of algal-derived bioproducts in the market.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Martin Kerner, Thorsten Wolff, Torsten Brinkmann
Summary: The efficiency of using enriched CO2 from flue gas for large-scale production of green microalgae has been studied. The results show that the use of membrane devices and static mixers can effectively improve the CO2 recovery rate and maintain the suitable pH and temperature during cultivation, achieving a more economical and sustainable microalgae production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rui Ma, Ji Li, Rd Tyagi, Xiaolei Zhang
Summary: This review summarizes the microorganisms capable of using CO2 and CH4 to produce PHAs, illustrating the production process, factors influencing it, and discussing optimization techniques. It identifies the challenges and future prospects for developing economically viable PHAs production using GHGs as a carbon source.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Bing Wang, Peng Zhang, Xu Guo, Xu Bao, Junjie Tian, Guomin Li, Jian Zhang
Summary: The addition of zeolite in the co-composting of chicken manure and straw significantly reduced the emissions of ammonia and N2O, and increased the nitrate content. Zeolite also promoted the abundance of nitrification genes and inhibited the expression of denitrification genes.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rohit Dey, Franziska Ortiz Tena, Song Wang, Josef Martin Messmann, Christian Steinweg, Claudia Thomsen, Clemens Posten, Stefan Leu, Matthias S. Ullrich, Laurenz Thomsen
Summary: This study investigated the operation of a 1000L microalgae-based membrane photobioreactor system for continuous secondary wastewater treatment. The research focused on a green microalgae strain called Desmodesmus sp. The study aimed to understand key trends and optimization strategies by conducting experiments in both summer and winter seasons. The findings showed that maintaining low cell concentrations during periods of light inhibition was beneficial for nutrient uptake rates. Effective strategies for enhancing algae-based wastewater treatment included cell mass recycling and adjusting dilution rates based on light availability.
BIORESOURCE TECHNOLOGY
(2024)
