Article
Food Science & Technology
Xiaosan Wang, Xiaohan Wang, Dan Xie
Summary: The study investigated the feasibility of using ethanolamine as substrate to reduce acidity of high-acid rice bran oil, with calcium oxide identified as the best catalyst. Under optimized conditions, the deacidified RBO contained 1.1% FFA and value-added products fatty ethanolamides were formed, potentially reducing deacidification costs significantly. This novel pretreatment method using calcium oxide as catalyst was found to be effective, economical, and environmentally friendly.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Organic
Lei-Yang Zhang, Nai-Xing Wang, Yue-Hua Wu, Zhan Yan, Xue-Wang Gao, Ke Feng, Bao-Cai Xu, Yalan Xing, Pei-Jia Wang, Yao Zhang, Le-Le Gao
Summary: The synthesis of bioactive amides was achieved by generating secondary amides with an aldehyde group through the reaction of aldehydes and secondary amines. Various (hetero)aryl aldehydes and aliphatic aldehydes were successfully converted into the desired products in moderate to excellent yields. A plausible mechanism involving a Cu(I/II/III) catalytic cycle combined with radical rearrangement was proposed and confirmed with the detection of four key intermediates by high-resolution mass spectrometry.
Article
Chemistry, Multidisciplinary
Ryan T. McGuire, Travis Lundrigan, Joshua W. M. MacMillan, Katherine N. Robertson, Arun A. Yadav, Mark Stradiotto
Summary: This article introduces a new efficient protocol for the C-N cross-coupling of amides and (pseudo)halide-substituted acetophenones. The reaction can be conducted at room temperature and employs nickel catalysts and organic amine bases. Stoichiometric experiments support a Ni-0/II pathway, and the combination of DBU/NaTFA enables room-temperature amide cross-couplings.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Multidisciplinary
Geyang Song, Qi Li, Ding-Zhan Nong, Jiameng Song, Gang Li, Chao Wang, Jianliang Xiao, Dong Xue
Summary: This paper describes a photochemical C-N coupling reaction of less reactive aryl chlorides with primary and secondary amides using a Ni catalyst without an external photocatalyst. The reaction proceeds under light irradiation (390-395 nm) with a soluble organic amine as the base, resulting in the successful synthesis of a wide range of N-aryl amides from (hetero)aryl chlorides. Mechanistic studies suggest that the amidation occurs via a Ni(I)-Ni(III) catalytic cycle.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Chemistry, Organic
Sumi Changmai, Tribeni Gogoi, Jyotshna Phukon, Bipul Das, Sanjib Gogoi
Summary: This article describes the first use of sulfoxonium ylides for the synthesis of alpha-ketoamides via a Ru(ii)-catalyzed amidation reaction with amines. Interestingly, when sulfoxonium ylides were reacted with 2-phenylindoles using the same Ru(ii)-catalyzed reaction, indolo[2,1-a]isoquinolines were obtained instead of alpha-ketoamides.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Physical
S. M. A. Hakim Siddiki, Md. Nurnobi Rashed, Abeda Sultana Touchy, Md. A. R. Jamil, Yuan Jing, Takashi Toyao, Zen Maeno, Ken-ichi Shimizu
Summary: Nb2O5 was identified as the most effective catalyst for the hydrolysis of acetamide to acetic acid, due to its ability to readily activate the carbonyl bond through Lewis acid sites. This method offers synthetic advantages including simple operation, catalyst recyclability, lack of additives, solvent-free conditions, and applicability to a wide range of substrates.
CATALYSIS SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Elisabetta Brenna, Valeria De Fabritiis, Fabio Parmeggiani, Francesca Tentori, Davide Tessaro
Summary: This work presents the synthesis of oleoyl ethanolamide, an FDA-approved dietary supplement for weight loss, using lipase-mediated conversion of oleic acid. The process utilizes a packed-bed reactor with commercial lipase Lipozyme 435 in continuous flow mode, which improves reaction yield and catalyst productivity. The nontoxic and renewable solvent limonene is used, and the biocatalyst demonstrates stability and efficiency after more than 157 hours of continuous operation. The target compound is selectively obtained by simple filtration, showing high purity and isolation yield, while the reaction byproducts remain in the solution.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Li Liu, Yingdong Zhou, Lixian Guo, Guiying Li, Changwei Hu
Summary: A method for producing nitrogen-containing compounds from natural microalgae was developed and the effects of different conditions on the yield were studied. Addition of ZrO2 resulted in an increase in the yields of fatty amides and nitriles, while the total yield of fatty acids decreased.
Article
Chemistry, Multidisciplinary
Naoya Takahashi, Airi Takahashi, Naoyuki Shimada
Summary: This paper describes a method for peptide bond formation from α-amino acid methyl esters using boronic acid catalysts. The catalysis shows high selectivity for β-hydroxy-α-amino esters, resulting in peptides with high yields and tolerance for various functional groups. This hydroxy-directed peptide bond formation could be used for oligopeptide synthesis. This is the first successful example of organoboron-catalyzed peptide bond formation from α-amino acid-derived inert esters.
CHEMICAL COMMUNICATIONS
(2023)
Article
Chemistry, Organic
Alejandro Cervantes-Reyes, Aaron C. Smith, Gary M. Chinigo, David C. Blakemore, Michal Szostak
Summary: This study reports a method for the direct synthesis of nitrogen-containing heteroaromatic biaryls by decarbonylative Pd-catalyzed Suzuki cross-coupling. The practical and modular nature of this method enables the synthesis of diverse heterobiaryl products in excellent yields.
Article
Chemistry, Multidisciplinary
Fangyuan Chen, Junyuan Tang, Yinhui Wei, Jingyuan Tian, Hui Gao, Wei Yi, Zhi Zhou
Summary: This study successfully utilized alpha-allenols as innovative three-carbon annulation components in the Rh(iii)-catalyzed redox-neutral C-H coupling of N-phenoxyacetamides, leading to the assembly of 4-alkylidene chroman-2-ol frameworks through an unusual [3+3] annulation. Mechanistic studies revealed that synergistic coordination modes between the dual directing groups and the rhodium metal center are responsible for the observed exclusive selectivity in this transformation.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Organic
Xiyang Cao, Zhiguo Zhang, Jingya Li, Bingbing Shi, Mengjuan Li, Guisheng Zhang, Xingjie Zhang
Summary: An efficient and convenient method for the synthesis of indolo[2,1-a]isoquinolines was reported. This reaction involved the Rh(III)-catalyzed double aryl C(sp2)-H bond and N-H activation and annulation, with the presence of Cu(OAc)2 as the oxidant and under heating conditions. Notably, 1,3-diarylurea could serve as a precursor for the generation of two arylamine molecules, diverging from previous studies.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Qun-Liang Zhang, Wenxin Liu, Yirong Zhou, Fang-Lin Zhang
Summary: An unprecedented reductive amidation reaction of chloroalkanes with nitroarenes was achieved by combining iron catalysis with visible-light photoredox catalysis. This environmentally benign protocol enabled the direct synthesis of diverse N-aryl amides using commercially inexpensive nitroarenes and chloroalkanes under mild conditions. This method offers advantages such as avoiding the use of external reductants and photocatalysts, simple manipulations, low cost, high step economy, and good functional group tolerance. Additionally, a preliminary investigation into the reaction mechanism revealed the isolation of a nitrone as a possible active intermediate, suggesting a successive two-step rearrangement in the catalytic cycle.
Article
Chemistry, Organic
Shona Banjo, Keisuke Nakata, Eiko Nakasuji, Soichiro Yasui, Noritaka Chida, Takaaki Sato
Summary: This study reports a copper-catalyzed electrophilic enamidation starting from alkynes. Hydrozirconation of an alkyne with the Schwartz reagent forms a vinyl zirconium intermediate, which undergoes a copper-catalyzed electrophilic enamidation with dioxazolones. The high functional group tolerance of hydrozirconation enables the use of functionalized alkynes, including esters. The developed conditions are successfully applied to synthesize partial structures found in biologically active natural products.
Article
Chemistry, Organic
Haipeng Hu, Cuilin Wang, Xin Wu, Yangu Liu, Guizhou Yue, Gehong Su, Juhua Feng
Summary: The catalytic alpha-C-H fluorination of aryl acetic acids was achieved with good functional group tolerance in the presence of a boron catalyst. A series of alpha-fluoro aryl acetic acids were obtained in a single step with high yields (up to 96%). The catalytic reaction was employed for the synthesis of bioactive molecules and the modification of profen drugs.
ORGANIC CHEMISTRY FRONTIERS
(2022)
Article
Agricultural Engineering
Yinping Xiang, Meiying Jia, Rui Xu, Jialu Xu, Lele He, Haihao Peng, Weimin Sun, Dongbo Wang, Weiping Xiong, Zhaohui Yang
Summary: This study investigated the impact of the non-antibiotic pharmaceutical carbamazepine on antibiotic resistance genes (ARGs) during anaerobic digestion. The results showed that carbamazepine induced the enrichment of ARGs and increased the abundance of bacteria carrying these genes. It also facilitated microbial aggregation and intercellular communication, leading to an increased frequency of ARGs transmission. Moreover, carbamazepine promoted the acquisition of ARGs by pathogens and elevated their overall abundance.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Weixin Zhao, Tianyi Hu, Hao Ma, Dan Li, Qingliang Zhao, Junqiu Jiang, Liangliang Wei
Summary: This review summarizes the effects and potential mechanisms of biochar on microbial behavior in AD systems. The addition of biochar has been found to promote microbial colonization, alleviate stress, provide nutrients, and enhance enzyme activity. Future research directions include targeted design of biochar, in-depth study of microbial mechanisms, and improved models.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Christina Karmann, Anna Magrova, Pavel Jenicek, Jan Bartacek, Vojtech Kouba
Summary: This review assesses nitrogen removal technologies in reject water treatment, highlighting the differences in environmental impacts and economic benefits. Partial nitritation-anammox shows potential for economic benefits and positive environmental outcomes when operated and controlled properly.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Wei-Hao Huang, Ying-Ju Chang, Duu-Jong Lee
Summary: This study modified pinecone biochar with layered double hydroxide (LDH) to enhance its adsorption capacity for heavy metal and phosphate ions. The LDH-biochar showed significantly improved adsorption capacities for Pb2+ and phosphate, and a slight increase for Cu2+ and Co2+. The LDH layer enhanced the adsorption through various mechanisms.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Chao Song, Fanfan Cai, Shuang Yang, Ligong Wang, Guangqing Liu, Chang Chen
Summary: This paper developed a machine learning model to predict the biochemical methane potential during anaerobic digestion. Model analysis identified lignin content, organic loading, and nitrogen content as key attributes for methane production prediction. For feedstocks with high cellulose content, early methane production is lower but can be improved by prolonging digestion time. Moreover, lignin content exceeding a certain value significantly inhibits methane production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sang Min Lee, Ju Young Lee, Ji-Sook Hahn, Seung-Ho Baek
Summary: This study successfully developed an efficient platform strain using Yarrowia lipolytica for the bioconversion of renewable resources into adipic acid, achieving a remarkable increase in production level.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Sefkan Kendir, Matthias Franzreb
Summary: This study presents a novel approach using magnetic separation to efficiently harvest freshwater microalgae, Chlorella vulgaris. By combining pH-induced calcium phosphate precipitation with cheap natural magnetite microparticles, harvesting efficiencies up to 98% were achieved in the model medium.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Ishaq Kariim, Ji-Yeon Park, Wajahat Waheed Kazmi, Hulda Swai, In-Gu Lee, Thomas Kivevele
Summary: The impact of reaction temperature, residence time, and ethanol: acetone on the energy compositions and yield enhancement of biocrudes was investigated. The results showed that under appropriate conditions, biocrudes with high energy and low oxygen content can be obtained, indicating a high potential for utilization.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xiyue Zhang, Xiyao Li, Liang Zhang, Yongzhen Peng
Summary: Intermittent aeration is an innovative approach to enhance nitrogen removal in low carbon-to-nitrogen ratio municipal sewage, providing an efficient strategy for the continuous plug-flow AOA process.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Xu Yang, Mahmoud Mazarji, Mengtong Li, Aohua Li, Ronghua Li, Zengqiang Zhang, Junting Pan
Summary: This study investigated the impact of magnetite on the nitrogen cycle of pig manure biostabilisation. The addition of magnetite increased N2O emissions and decreased NH3 emissions during composting. It also increased the total nitrogen content but should be considered for its significant increase in N2O emissions in engineering practice.
BIORESOURCE TECHNOLOGY
(2024)
Review
Agricultural Engineering
Ty Shitanaka, Haylee Fujioka, Muzammil Khan, Manpreet Kaur, Zhi-Yan Du, Samir Kumar Khanal
Summary: The market value of microalgae has exponentially increased in the past two decades, thanks to their applications in various industries. However, the supply of high-value microalgal bioproducts is limited due to several factors, and strategies are being explored to overcome these limitations and improve microalgae production, thus increasing the availability of algal-derived bioproducts in the market.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Martin Kerner, Thorsten Wolff, Torsten Brinkmann
Summary: The efficiency of using enriched CO2 from flue gas for large-scale production of green microalgae has been studied. The results show that the use of membrane devices and static mixers can effectively improve the CO2 recovery rate and maintain the suitable pH and temperature during cultivation, achieving a more economical and sustainable microalgae production.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rui Ma, Ji Li, Rd Tyagi, Xiaolei Zhang
Summary: This review summarizes the microorganisms capable of using CO2 and CH4 to produce PHAs, illustrating the production process, factors influencing it, and discussing optimization techniques. It identifies the challenges and future prospects for developing economically viable PHAs production using GHGs as a carbon source.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Bing Wang, Peng Zhang, Xu Guo, Xu Bao, Junjie Tian, Guomin Li, Jian Zhang
Summary: The addition of zeolite in the co-composting of chicken manure and straw significantly reduced the emissions of ammonia and N2O, and increased the nitrate content. Zeolite also promoted the abundance of nitrification genes and inhibited the expression of denitrification genes.
BIORESOURCE TECHNOLOGY
(2024)
Article
Agricultural Engineering
Rohit Dey, Franziska Ortiz Tena, Song Wang, Josef Martin Messmann, Christian Steinweg, Claudia Thomsen, Clemens Posten, Stefan Leu, Matthias S. Ullrich, Laurenz Thomsen
Summary: This study investigated the operation of a 1000L microalgae-based membrane photobioreactor system for continuous secondary wastewater treatment. The research focused on a green microalgae strain called Desmodesmus sp. The study aimed to understand key trends and optimization strategies by conducting experiments in both summer and winter seasons. The findings showed that maintaining low cell concentrations during periods of light inhibition was beneficial for nutrient uptake rates. Effective strategies for enhancing algae-based wastewater treatment included cell mass recycling and adjusting dilution rates based on light availability.
BIORESOURCE TECHNOLOGY
(2024)