Improved chemical synthesis of hydrophobic Aβ peptides using addition of C-terminal lysines later removed by carboxypeptidase B

One-pot total chemical synthesis of human α-synuclein

(2013) Bruno Fauvet et al.   CHEMICAL COMMUNICATIONS

Is the Amyloid Hypothesis of Alzheimer's disease therapeutically relevant?

(2012) Andrew F. Teich et al.   BIOCHEMICAL JOURNAL

Alzheimer’s Disease Amyloid β-Protein Mutations and Deletions That Define Neuronal Binding/Internalization as Early Stage Nonfibrillar/Fibrillar Aggregates and Late Stage Fibrils

(2012) Joseph F. Poduslo et al.   BIOCHEMISTRY

Processive proteolysis by γ-secretase and the mechanism of Alzheimer’s disease

(2012) Michael S. Wolfe   BIOLOGICAL CHEMISTRY

The Amyloid Beta Peptide: A Chemist’s Perspective. Role in Alzheimer’s and Fibrillization

(2012) I. W. Hamley   CHEMICAL REVIEWS

Early accumulation of intracellular fibrillar oligomers and late congophilic amyloid angiopathy in mice expressing the Osaka intra-Aβ APP mutation

(2012) L Kulic et al.   Translational Psychiatry

Total Chemical Synthesis of an Integral Membrane Enzyme: Diacylglycerol Kinase fromEscherichia coli

(2011) Sunanda Lahiri et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Japanese Mutant Aβ (ΔE22-Aβ1−39) Forms Fibrils Instantaneously, with Low-Thioflavin T Fluorescence: Seeding of Wild-Type Aβ1−40into Atypical Fibrils by ΔE22-Aβ1−39

(2011) Adam L. Cloe et al.   BIOCHEMISTRY

Self-assembly pathways of E22Δ-type amyloid β peptide mutants generated from non-aggregative O-acyl isopeptide precursors

(2011) Youhei Sohma et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Osaka FAD Mutation E22Δ Leads to the Formation of a Previously Unknown Type of Amyloid β Fibrils and Modulates Aβ Neurotoxicity

(2011) Oxana Yu. Ovchinnikova et al.   JOURNAL OF MOLECULAR BIOLOGY

Slow Amyloid Nucleation via α-Helix-Rich Oligomeric Intermediates in Short Polyglutamine-Containing Huntingtin Fragments

(2011) Murali Jayaraman et al.   JOURNAL OF MOLECULAR BIOLOGY

Toward the total chemical synthesis of the cancer protein NY-ESO-1

(2010) Paul W. R. Harris et al.   BIOPOLYMERS

Aβ(1–40) Forms Five Distinct Amyloid Structures whose β-Sheet Contents and Fibril Stabilities Are Correlated

(2010) Ravindra Kodali et al.   JOURNAL OF MOLECULAR BIOLOGY

Direct Solid-Phase Synthesis of the β-Amyloid (1−42) Peptide Using Controlled Microwave Heating

(2010) Bernadett Bacsa et al.   JOURNAL OF ORGANIC CHEMISTRY

Improved Fmoc-based solid-phase synthesis of homologous peptide fragments of human and mouse prion proteins

(2010) Dolors Grillo-Bosch et al.   JOURNAL OF PEPTIDE SCIENCE

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

(2010) Asad Jan et al.   Nature Protocols

The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42

(2009) Verena H. Finder et al.   JOURNAL OF MOLECULAR BIOLOGY

Aβ43 is more frequent than Aβ40 in amyloid plaque cores from Alzheimer disease brains

(2009) Hedvig Welander et al.   JOURNAL OF NEUROCHEMISTRY

A new amyloid β variant favoring oligomerization in Alzheimer's-type dementia

(2008) Takami Tomiyama et al.   ANNALS OF NEUROLOGY

Solid-Phase Synthesis of Difficult Peptide Sequences at Elevated Temperatures: A Critical Comparison of Microwave and Conventional Heating Technologies

(2008) Bernadett Bacsa et al.   JOURNAL OF ORGANIC CHEMISTRY