Chemical and biological methods to detect post-translational modifications of arginine

Monitoring of Protein Arginine Deiminase Activity by Using Fluorescence Quenching: Multicolor Visualization of Citrullination

(2013) Qunzhao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Technologies and challenges in large-scale phosphoproteomics

(2013) Kasper Engholm-Keller et al.   PROTEOMICS

Novel small molecule protein arginine deiminase 4 (PAD4) inhibitors

(2012) Murat Bozdag et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

(2012) John L McElwee et al.   BMC CANCER

A Selenium-Based Click AdoMet Analogue for Versatile Substrate Labeling with Wild-Type Protein Methyltransferases

(2012) Sophie Willnow et al.   CHEMBIOCHEM

Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis

(2012) M. A. Moscarello et al.   Disease Models & Mechanisms

Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity

(2012) Yuji Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bioorthogonal Profiling of Protein Methylation Using Azido Derivative of S-Adenosyl-l-methionine

(2012) Kabirul Islam et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Se-Adenosyl-l-selenomethionine Cofactor Analogue as a Reporter of Protein Methylation

(2012) Ian R. Bothwell et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Seeing Citrulline: Development of a Phenylglyoxal-Based Probe To Visualize Protein Citrullination

(2012) Kevin L. Bicker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling Genome-Wide Chromatin Methylation with Engineered Posttranslation Apparatus within Living Cells

(2012) Rui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Probing adenylation: using a fluorescently labelled ATP probe to directly label and immunoprecipitate VopS substrates

(2012) Daniel M. Lewallen et al.   Molecular BioSystems

Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor   target gene activation

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

(2011) Kabirul Islam et al.   ACS Chemical Biology

Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitor

(2011) Alexander A. Chumanevich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Autodeimination of Protein Arginine Deiminase 4 Alters Protein–Protein Interactions but Not Activity

(2011) Jessica L. Slack et al.   BIOCHEMISTRY

Protein deiminases: New players in the developmentally regulated loss of neural regenerative ability

(2011) Sigrun Lange et al.   DEVELOPMENTAL BIOLOGY

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes

(2011) N. Rabbani et al.   DIABETES

Activity Control of the ClpC Adaptor McsB in Bacillus subtilis

(2011) A. K. W. Elsholz et al.   JOURNAL OF BACTERIOLOGY

Citrullination of Inhibitor of Growth 4 (ING4) by Peptidylarginine Deminase 4 (PAD4) Disrupts the Interaction between ING4 and p53

(2011) Qin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

(2011) Van C. Willis et al.   JOURNAL OF IMMUNOLOGY

A Chemical Reporter for Protein AMPylation

(2011) Markus Grammel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Discovery of peptidylarginine deiminase-4 substrates by protein array: antagonistic citrullination and methylation of human ribosomal protein S2

(2011) Qin Guo et al.   Molecular BioSystems

Detection and Quantification of Citrullinated Chemokines

(2011) Eva A. V. Moelants et al.   PLoS One

ADP-ribosylation of arginine

(2010) Sabrina Laing et al.   AMINO ACIDS

A targeted mass spectrometry-based approach for the identification and characterization of proteins containing α-aminoadipic and γ-glutamic semialdehyde residues

(2010) Juan D. Chavez et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

A technique for the specific enrichment of citrulline-containing peptides

(2010) Astrid E.V. Tutturen et al.   ANALYTICAL BIOCHEMISTRY

Enzymatic Site-Specific Functionalization of Protein Methyltransferase Substrates with Alkynes for Click Labeling

(2010) Wibke Peters et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Substrate Specificity and Kinetic Studies of PADs 1, 3, and 4 Identify Potent and Selective Inhibitors of Protein Arginine Deiminase 3

(2010) Bryan Knuckley et al.   BIOCHEMISTRY

Protein arginine deiminase 4: a target for an epigenetic cancer therapy

(2010) Jessica L. Slack et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Chemical Method for Labeling Lysine Methyltransferase Substrates

(2010) Olivier Binda et al.   CHEMBIOCHEM

Increased Glycation and Oxidative Damage to Apolipoprotein B100 of LDL Cholesterol in Patients With Type 2 Diabetes and Effect of Metformin

(2010) N. Rabbani et al.   DIABETES

Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress

(2010) O. Brouwers et al.   DIABETOLOGIA

Histone arginine methylation

(2010) Alessandra Di Lorenzo et al.   FEBS LETTERS

Dysregulation of PRMT1 and PRMT6, Type I arginine methyltransferases, is involved in various types of human cancers

(2010) Masanori Yoshimatsu et al.   INTERNATIONAL JOURNAL OF CANCER

Photorhabdus luminescens Toxins ADP-Ribosylate Actin and RhoA to Force Actin Clustering

(2010) A. E. Lang et al.   SCIENCE

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

ADP-ribosylation of human defensin HNP-1 results in the replacement of the modified arginine with the noncoded amino acid ornithine

(2009) L. A. Stevens et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combining affinity purification by ADP-ribose-binding macro domains with mass spectrometry to define the mammalian ADP-ribosyl proteome

(2009) N. Dani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR

(2009) J. Fuhrmann et al.   SCIENCE

Immunological Detection of Nω-(Carboxymethyl)arginine by a Specific Antibody

(2008) Katsumi Mera et al.   Annals of the New York Academy of Sciences

Smoking increases peptidylarginine deiminase 2 enzyme expression in human lungs and increases citrullination in BAL cells

(2008) D Makrygiannakis et al.   ANNALS OF THE RHEUMATIC DISEASES

Chemical mechanisms of histone lysine and arginine modifications

(2008) Brian C. Smith et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Mammalian ADP-ribosyltransferases and ADP-ribosylhydrolases

(2008) Friedrich Koch-Nolte   Frontiers in Bioscience-Landmark

In Situ Generation of a Bisubstrate Analogue for Protein Arginine Methyltransferase 1

(2008) Tanesha Osborne et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synovial detection and autoantibody reactivity of processed citrullinated isoforms of vimentin in inflammatory arthritides

(2008) K. Tilleman et al.   RHEUMATOLOGY

An improved synthesis of haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4)

(2008) Corey P. Causey et al.   TETRAHEDRON LETTERS

Detection of citrullinated proteins in synovial fluids derived from patients with rheumatoid arthritis by proteomics-based analysis

(2008) Y. Tabushi et al.   ANNALS OF CLINICAL BIOCHEMISTRY