Article
Multidisciplinary Sciences
Kevin T. Du Clos, Brad J. Gemmell, Sean P. Collin, John H. Costello, John O. Dabiri, Kelly R. Sutherland
Summary: Many fishes and physonect siphonophores employ distinct swimming modes for routine swimming and predator escape. In this study, the researchers compared the performances of asynchronous and synchronous swimming in the physonect siphonophore Nanomia bijuga. They found that synchronous swimming produced higher speeds and accelerations at the expense of higher costs of transport, while asynchronous swimming had lower energy consumption.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Biotechnology & Applied Microbiology
Sha Wu, Fengfei Ma, Jinxin He, Qing X. Li, Bruce D. Hammock, Jiesheng Tian, Ting Xu
Summary: Magnetic nanoparticles, such as antibody-modified magnetosomes, have a high likelihood of interacting with target molecules. In this study, magnetosomes biomineralized by magnetotactic bacteria were functionalized with nanobodies for the analysis of the insecticide fipronil. The Nb-magnetosomes showed binding capability to fipronil-horseradish peroxidase and were successfully used in an enzyme-linked immunosorbent assay for fipronil detection in water samples.
JOURNAL OF NANOBIOTECHNOLOGY
(2021)
Article
Engineering, Environmental
Jiawei Hu, Wence Yang, Lu Li, Yan Liu
Summary: This study investigated the growth, magnetic production, and denitrification activity of Magnetospirillum gryphiswaldense strain MSR-1 under conditions similar to urban domestic sewage. The results showed that sodium lactate was the best carbon source for denitrification, and nitrate was the best nitrogen source. MSR-1 effectively removed nitrate, with a low C/N demand, and the optimal denitrification conditions were similar to those used in the sewage treatment system.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Engineering, Multidisciplinary
Shigeru Kuroda, Nariya Uchida, Toshiyuki Nakagaki
Summary: This study found that a centipede can flexibly generate gait patterns with varying directions of locomotory waves, depending on locomotion speed and the physical conditions of the terrain. Additionally, a new type of swimming gait for centipedes was discovered. The research showed that gait patterns are associated with control of stride length.
BIOINSPIRATION & BIOMIMETICS
(2022)
Article
Automation & Control Systems
Priyanka Sharan, Charlie Maslen, Berk Altunkeyik, Ivan Rehor, Juliane Simmchen, Thomas D. Montenegro-Johnson
Summary: Hydrogels have gained attention due to their biocompatible material properties, adjustable porosity, ease of functionalization, tunable shape, and Young's moduli. Research has shown the potential of conferring out-of-equilibrium properties to hydrogels on the microscale for a broad range of biomedical applications. This study presents a simple strategy to integrate multiple swimming modes into catalase-propelled hydrogel bodies, produced via stop-flow lithography (SFL), and investigates the dynamics resulting from bubble expulsion.
ADVANCED INTELLIGENT SYSTEMS
(2021)
Article
Microbiology
Theresa Zwiener, Frank Mickoleit, Marina Dziuba, Christian Rueckert, Tobias Busche, Jorn Kalinowski, Damien Faivre, Rene Uebe, Dirk Schueler
Summary: This study demonstrates the use of allelic replacement method based on homologous recombination for large-scale genome editing in Magnetospirillum gryphiswaldense. Through analysis of 24 deletion mutants, genes and regions inside and outside the magnetosome island irrelevant for magnetosome biosynthesis were identified. The findings suggest that a contiguous stretch of about 100 kb could be functionally substituted by a compact 38 kb cassette, which will be beneficial for future large-scale genome editing and genetic engineering of magnetosome biosynthesis.
Article
Chemistry, Multidisciplinary
Siyun Liu, Qingjie Qi, Yingjie Liu, Jiamei Chai, Zuo Sun, Tianfang Ma, Dan Li, Wenhao Xian
Summary: This paper introduces an electromagnetic switching multiple grasping modes robot hand that has a universal grasping function and can be applied in various fields. The incompatible grasping modes are integrated through ingenious design and self-adaptive grasping mode is achieved by the partial effective transmission mechanism. The ESMGM hand not only has multiple grasping functions but also has equitable grasping motions, adequate grasping forces, and stable grasping effects.
APPLIED SCIENCES-BASEL
(2022)
Article
Engineering, Biomedical
Sabine Rosenfeldt, Frank Mickoleit, Cornelia Joerke, Joachim H. Clement, Simon Markert, Valerie Jerome, Stephan Schwarzinger, Ruth Freitag, Dirk Schueler, Rene Uebe, Anna S. Schenk
Summary: This study characterizes a multi-step purification protocol for bacterial magnetosomes (MS) in terms of purity, iron content, size, and polydispersity. The potential cytotoxic effects of isolated MS when incubated with mammalian cells are also addressed. The study helps establish prerequisites for real-world applications of magnetosomes in biotechnology and biomedicine by providing a detailed overview of the process-structure relationship during the isolation of MS.
ACTA BIOMATERIALIA
(2021)
Article
Biology
Matthew E. Meech, Claudia E. Mills, Steven H. D. Haddock, Robert W. Meech
Summary: Members of the Rhopalonematidae family exhibit dual swimming modes, with significant differences in neural anatomy, kinematics, and physiology among species. These behavioral differences are related to the position of the different clades on a ribosomal DNA-based phylogenetic tree.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2021)
Article
Physics, Fluids & Plasmas
Chenji Li, Brato Chakrabarti, Pedro Castilla, Achal Mahajan, David Saintillan
Summary: This study presents an integrated chemomechanical model of freely swimming spermatozoa that produces spontaneous oscillations with realistic beating patterns and trajectories. The swimming velocity is found to exhibit two maxima associated with distinct swimming modes, and the model also provides an estimate of swimming efficiency, which peaks at low sperm number.
PHYSICAL REVIEW FLUIDS
(2023)
Article
Engineering, Marine
Kai Ren, Jiancheng Yu, Zhier Chen, Hongbo Li, Hao Feng, Kai Liu
Summary: This study numerically investigated the relationship between energetically advantageous formations and swimming modes of fish by simulating two self-propelled fish at different initial spacings. The study identified three types of beneficial formations and explained the intrinsic mechanisms of individual benefit for each type through the analysis of swimming performance, velocity clouds, and vortex evolution. It provides new insights into the appropriate configuration of fish for different swimming modes in nature.
Article
Mathematics, Applied
V. A. Khramenkov, A. S. Dmitrichev, V. I. Nekorkin
Summary: This paper investigates a power grid with three synchronous generators, in which one generator is closer to the load than the others. A reduced model is derived to analyze the stable synchronous and asymmetric modes of the grid. The non-local stability of the asymmetric synchronous modes and the effect of disturbances and noise on mode switching are studied.
Article
Optics
Andrey B. Evlyukhin, Maria A. Poleva, Alexei Prokhorov, Kseniia Baryshnikova, Andrey E. Miroshnichenko, Boris N. Chichkov
Summary: A general strategy for realizing electric and magnetic quasi-trapped modes at the same spectral position is presented, allowing switching between the modes by changing the polarization of incident light. The strategy is based on two stages: determining conditions for trapped modes and exciting them by introducing weakness in nanoparticles, enabling control and localization of optical energy at sub-wavelength scale.
LASER & PHOTONICS REVIEWS
(2021)
Article
Engineering, Electrical & Electronic
Lei Xu, Z. Q. Zhu
Summary: This article proposes a novel inverter nonlinearity compensation method for open-winding machines, utilizing analysis of the nonlinearity of dual inverters and compensating through alternating switching modes. This method does not require offline measurement of parameters and can handle variations in different operation conditions, overcoming issues in conventional methods.
IEEE JOURNAL OF EMERGING AND SELECTED TOPICS IN POWER ELECTRONICS
(2022)
Article
Biology
Agnese Codutti, Mohammad A. Charsooghi, Elisa Cerda-Donate, Hubert M. Taieb, Tom Robinson, Damien Faivre, Stefan Klumpp, Raymond E. Goldstein
Summary: In this study, magnetically steerable microswimmers, specifically magnetotactic bacteria, were trapped in micrometer-sized microfluidic chambers and their motion was tracked and analyzed. The researchers observed a variety of different trajectories, depending on the chamber size and the strength of the magnetic field. Combining experimental observations with simulations, they explained the diversity of trajectories by the interplay between wall interactions and the magnetic torque. The study also highlighted the importance of single-cell tracking for understanding motility patterns and established a basis for analyzing and predicting microswimmer motility in more complex environments.
Review
Chemistry, Multidisciplinary
Pierre-Luc Latreille, Marine Le Goas, Sina Salimi, Jordan Robert, Gregory De Crescenzo, Daria C. Boffito, Vincent A. Martinez, Patrice Hildgen, Xavier Banquy
Summary: This review provides a systematic analysis of ongoing debates in protein corona research, highlighting the correlation between protein corona characteristics and physicochemical factors of the NP-protein system, as well as the impact of experimental design on the reversibility of binding.
Article
Chemistry, Physical
Reece Nixon-Luke, Jochen Arlt, Wilson C. K. Poon, Gary Bryant, Vincent A. Martinez
Summary: This study systematically investigates the capability of Differential Dynamic Microscopy (DDM) to characterize particle dynamics in turbid colloidal suspensions, finding that DDM can obtain reliable diffusion coefficients at higher particle concentrations compared to other techniques. The research also reveals the appearance of short-time and long-time processes as turbidity increases, which can be used to estimate the particle size of non-interacting particles. Additionally, a simple theoretical framework, ms-DDM, is provided for turbid samples, taking into account multiple scattering.
Article
Chemistry, Physical
Ian Williams, Erdal C. Oguz, Hartmut Loewen, Wilson C. K. Poon, C. Patrick Royall
Summary: Colloids can be considered as big atoms and provide good models for atomic and molecular systems. Colloidal hard disks, serving as good models for 2D materials, have received relatively little attention in rheology despite being well-characterized in phase behavior. This study measures the shear rheology of quasi-hard-disk colloids in extreme confinement using a novel experimental setup and computer simulations. The results show that the rheological behavior of the confined system is similar to unconfined 2D and 3D hard particle systems, with the occurrence of dynamic yield stress and shear thinning.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Pierre-Luc Latreille, Jean-Michel Rabanel, Marine Le Goas, Sina Salimi, Jochen Arlt, Shunmoogum A. Patten, Charles Ramassamy, Patrice Hildgen, Vincent A. Martinez, Xavier Banquy
Summary: A new theoretical framework that utilizes differential dynamic microscopy (DDM) in fluorescence imaging mode is proposed for quantifying protein adsorption and aggregation on nanoparticles (NP). This methodology provides insights into the thermodynamic and kinetic properties of the protein corona (PC) in vitro and in vivo.
ADVANCED MATERIALS
(2022)
Article
Physics, Multidisciplinary
Yujie Jiang, Soichiro Makino, John R. Royer, Wilson C. K. Poon
Summary: By mixing colloidal gel with larger non-Brownian grains, we have discovered a novel flow-switched bistability. Through confocal microscopy and rheology analysis, we observed that moderate shear results in gel collapse into disjoint globules, while fast shear creates a yield-stress gel with granular inclusions when the flow stops. We have mapped out the state diagram of this new material and demonstrated its behavior in separate mixtures with different particles and solvents.
PHYSICAL REVIEW LETTERS
(2022)
Article
Physics, Multidisciplinary
Gaspard Junot, Thierry Darnige, Anke Lindner, Vincent A. Martinez, Jochen Arlt, Angela Dawson, Wilson C. K. Poon, Harold Auradou, Eric Clement
Summary: This article investigates the movement and biofilm formation of motile bacteria on surfaces. Using a novel tracking technique, the researchers observed surface residence and escape behaviors. A motility model was proposed to explain the findings and provide new insights into surface trapping efficiency.
PHYSICAL REVIEW LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Jean-Michel Rabanel, Marziye Mirbagheri, Mateusz Olszewski, Guojun Xie, Marine Le Goas, Pierre-Luc Latreille, Hermine Counil, Vincent Herve, Rummenigge Oliveira Silva, Charlotte Zaouter, Vahid Adibnia, Mariana Acevedo, Marc J. Servant, Vincent A. Martinez, Shunmoogum A. Patten, Krzysztof Matyjaszewski, Charles Ramassamy, Xavier Banquy
Summary: This study demonstrates that bottle-brush polymers can efficiently cross the blood-brain barrier and penetrate dense tissues such as the brain. They have a faster translocation rate compared to nanospheres of similar composition. The ability of bottle-brush polymers to escape the vasculature compartment and exhibit higher penetration in brain tissues makes them promising drug carriers in the field of nanomedicine.
Article
Mechanics
Th. Larsen, A. L. Sobye, J. R. Royer, W. C. K. Poon, T. Larsen, S. J. Andreasen, A. D. Drozdov, J. D. C. Christiansen
Summary: This study investigates the influence of filler concentration and microphysics on the rheological properties of polydisperse flake-graphite particles suspended in Newtonian mineral oil. The experimental results show that the samples exhibit shear thinning under steady shear, and yielding behavior is observed for volume fractions above 0.18. Time-temperature superposition is observed using an Arrhenius-type horizontal shift factor, and a flow activation energy that depends on the graphite volume fraction is obtained, suggesting concentration-dependent contributions to relaxation processes in the suspensions. The flow curves are fitted by a constraint-based model, indicating that the flow behavior is controlled by frictional and adhesive contacts, with the model suggesting that the adhesive stress is temperature dependent.
JOURNAL OF RHEOLOGY
(2023)
Article
Biochemical Research Methods
Maryam Sheybanifard, Luis P. B. Guerzoni, Abdolrahman Omidinia-Anarkoli, Laura De Laporte, Johannes Buyel, Rut Besseling, Michiel Damen, Ad Gerich, Twan Lammers, Josbert M. M. Metselaar
Summary: Continuous flow manufacturing (CFM) has been proven advantageous in producing drug-loaded nanomedicines, and this study focused on the design and testing of a CFM setup for liposomal nanomedicines. The key parameters that affect the physicochemical characteristics of the liposomes were identified, including total flow rate, lipid concentration, residence time, pressure, and surface area. The integration of in-line measurement allowed for real-time monitoring and adjustment of key parameters during the manufacturing process.
Article
Pharmacology & Pharmacy
T. Rooimans, M. Damen, C. M. A. Markesteijn, C. C. L. Schuurmans, N. H. C. de Zoete, P. M. van Hasselt, W. E. Hennink, C. F. van Nostrum, M. Hermes, R. Besseling, H. Vromans
Summary: This study explores the extemporaneous preparation of a propofol emulsion without specialized manufacturing equipment to alleviate drug shortages during the COVID-19 pandemic. By adding liquid propofol drug substance and subsequent mixing, the evolution of droplet size and propofol distribution was monitored using Dynamic Light Scattering and Near Infrared Spectroscopy. Using response surface methodology, an optimum condition was found for a 4% w/v propofol formulation mixed for approximately 15 minutes at a 40-degree shaking angle. Extemporaneous compounding is a viable option for emergency supply of propofol during global drug shortages.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Social Issues
Wilson C. K. Poon, Tom C. B. McLeish
Summary: Quantum mechanics is often discussed in the context of science and religion, as it allows for theological claims by manipulating language and vocabulary. By mapping quantum mechanics to classical statistical mechanics, we can better understand this discussion. However, it is important to exercise caution in making distinct claims about quantum theology. Despite this, quantum insights can resonate with longstanding theological themes such as hiddenness and visualizability, suggesting a theology of science where scientists participate in the divine gaze.
Article
Physics, Fluids & Plasmas
Joost de Graaf, Kim William Torre, Wilson C. K. Poon, Michiel Hermes
Summary: Attractive colloids form gels, which are solidlike particle networks suspended in a fluid. The impact of gravity on the gelation process has been rarely studied. In this study, we used simulations to investigate the effect of gravity on gel formation. We found that gravity-induced flows disrupt gelation at low volume fractions, but above a critical volume fraction, the forming gel network dominates the dynamics. The settling of colloids does not significantly affect the final colloidal gel-like sediment.
Article
Chemistry, Physical
Joe J. Bradley, Vincent A. Martinez, Jochen Arlt, John R. Royer, Wilson C. K. Poon
Summary: Differential dynamic microscopy (DDM) can be used to measure the particle size distribution of multimodal suspensions without prior knowledge. By selectively analyzing different regions of DDM images, it is possible to separate and measure particles of different sizes.
Meeting Abstract
Dermatology
Ngai Ying Denise Li, Daniel Hodgson, David J. Moore, Sara Brown, Wilson Poon
BRITISH JOURNAL OF DERMATOLOGY
(2022)
