Review
Immunology
Lieke W. J. van den Elsen, Valerie Verhasselt
Summary: Human milk is considered the best diet for infant growth needs, and breastfeeding can have long-term metabolic outcomes. It is believed that human milk may regulate healthy growth by affecting adipose tissue development and metabolic balance, as well as influencing the interaction between gut microbiota, gut mucosa immunity, and adipose tissue. Further exploration of these interactions could lead to new preventative and therapeutic strategies for undernutrition and metabolic diseases.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Alistair McQueen, Javier Escuer, Andre Fensterseifer Schmidr, Ankush Aggarwal, Simon Kennedy, Christopher McCormick, Keith Oldroyd, Sean McGinty
Summary: Research indicates that the severity and time-course of restenosis are critically dependent on drug delivery strategy, and simply ramping up drug dose or prolonging drug release time is not sufficient to improve stent efficacy. Factors such as level of stent over-expansion and stent design features also influence restenosis development.
JOURNAL OF CONTROLLED RELEASE
(2022)
Article
Engineering, Biomedical
David P. Forrestal, Mark C. Allenby, Benjamin Simpson, Travis J. Klein, Maria A. Woodruff
Summary: This study presents a multiscale framework combining computational fluid dynamics, additive manufacturing, and a perfusion bioreactor system for engineering personalized volumetric tissue. By designing microscale 3D printed scaffold pore geometries and customizing perfusion bioreactors, tissue growth shaped like human calcaneus bones was achieved.
ADVANCED HEALTHCARE MATERIALS
(2022)
Article
Materials Science, Multidisciplinary
Prakhar Bandil, Franck J. Vernerey
Summary: Mechanical forces play a crucial role in the morphogenesis and growth of biological tissues, and understanding the interaction between mechanical forces and biological processes is of great importance. This study presents a continuum-scale model that describes the active mechanics and evolution of a cell population, which can capture the complex cross-talk between mechanical forces and biological processes.
JOURNAL OF THE MECHANICS AND PHYSICS OF SOLIDS
(2023)
Review
Oncology
Zodwa Dlamini, Richard Khanyile, Thulo Molefi, Botle Precious Damane, David Owen Bates, Rodney Hull
Summary: This review discusses how the processes of angiogenesis and neurogenesis are involved in cancer progression and are associated with poorer patient survival. These processes share signaling pathways and are often initiated together. Both processes require tissue changes and cell migration. They contribute to cancer progression by supplying nutrients and facilitating communication within the tumor. Additionally, they provide routes for cancer cells to migrate from the initial site to other areas of the body, leading to metastasis. The interplay between these processes in cancer development suggests the potential for targeted therapies.
Review
Immunology
Anna Estrada Brull, Camilla Panetti, Nicole Joller
Summary: Regulatory T cells (Tregs) not only suppress immune responses, but also promote tissue homeostasis, regeneration, and repair in non-lymphoid tissues. This review discusses the migration of Tregs to peripheral tissues, their functions in different tissues, and their interactions with non-immune cells.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Chemistry, Physical
Geoffrey Monet, Marie-Laure Bocquet, Lyderic Bocquet
Summary: The emergence of new nanoporous materials offers new avenues for water filtration and energy. A unified methodology for Non-Equilibrium classical Molecular Dynamic simulations (NEMD) is introduced to investigate the molecular mechanisms at the root of the advanced performances of these systems. By applying this methodology, a new type of synthetic Carbon NanoMembranes (CNM) is studied, which show outstanding performances for desalination and have potential for osmotic energy harvesting.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Physics, Multidisciplinary
Jin-Tao Jin, Kun Jiang, Hong Yao, Yi Zhou
Summary: This study demonstrates that spontaneous time-reversal symmetry breaking can arise naturally from the interaction between pair density wave ordering at multiple momenta and nesting of Fermi surfaces. The results have important implications for future experiments and real materials such as CsV3Sb5.
PHYSICAL REVIEW LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Gregory Beaune, Laura Sinkkonen, David Gonzalez-Rodriguez, Jaakko V. Timonen, Francoise Brochard-Wyart
Summary: Through studying the fusion of homogeneous cell aggregates and hybrid aggregates combining cells and microparticles, we discovered that the contact area does not vary linearly with time, but follows a power law with t(2/3). This can be explained by applying the fusion model of soft viscoelastic solid balls to viscoelastic liquid balls like jelly pearls. We also determined the self-diffusion coefficient of cells in a tissue by examining the asymmetric fusion between a homogeneous aggregate and a hybrid aggregate.
Article
Biochemistry & Molecular Biology
Navid Afrasiabian, Matthew Wei, Colin Denniston
Summary: Solid-state nanopore sensors are a promising solution for the rising demand for genome sequencing. Single-molecule sensing technologies require single-file translocation for accurate detection, and a previous study discovered a pulley effect in a pressure-driven translocation system. In this study, the pulley effect is further investigated in the presence of pressure-driven fluid flow and an opposing force from an electrostatic field to increase single-file capture probability.
Article
Chemistry, Physical
Diego Zapardiel, Pablo A. Garcia-Salaberri
Summary: The study highlights the importance of designing appropriate MEA porous media and interfaces in optimizing proton exchange fuel cells (PEFCs). By modeling water capillary transport and gas diffusion using a hybrid model, various characteristics under different conditions can be effectively captured, providing insights for enhancing PEFC performance.
JOURNAL OF POWER SOURCES
(2022)
Article
Physics, Fluids & Plasmas
Giulio Biroli, Patrick Charbonneau, Eric Corwin, Yi Hu, Harukuni Ikeda, Grzegorz Szamel, Francesco Zamponi
Summary: The random Lorentz gas (RLG) is a minimal model that demonstrates continuous localization transition in heterogeneous media and is also used to describe the discontinuous dynamical transition of glasses. In high-dimensional space, the caging transition in RLG precedes and prevents the percolation transition, while activated processes can destroy the glass transition in finite dimensions.
Review
Biochemistry & Molecular Biology
Simone Bini, Laura D'Erasmo, Alessia Di Costanzo, Ilenia Minicocci, Valeria Pecce, Marcello Arca
Summary: Angiopoietin-like proteins are known regulators of lipid metabolism, but recent evidence suggests they also play a role in regulating adipose tissue function. Dysfunction in adipose tissue, known as adiposopathy, is considered a main contributor to metabolic syndrome and its related complications. Understanding the role of ANGPTLs in adipocyte metabolism could provide insights into common cardiometabolic alterations associated with adiposopathy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Paolo Sebastiano Floris, Claudio Melis, Riccardo Rurali
Summary: Organic materials have gained attention in thermoelectric applications due to significant advances in their figure of merit (ZT), with values of 0.42 reported for PEDOT:PSS films treated with dimethyl sulfoxide and 0.25 obtained for PEDOT:Tosylate. This study uses classical molecular dynamics to investigate various PEDOT morphologies, both neutral and doped, and explores the impact of chain length distribution on thermal conductivity. The role of PSS in the bipolaronic state is also discussed, comparing it to the simpler case of Cl- counterion.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Physics, Fluids & Plasmas
M. Peret, N. Fedorczak, L. Vermare, WEST Team
Summary: This article investigates the effects of the presence and position of an X-point on plasma rotation in tokamaks. A reduced model of turbulence in a shear flow is derived and verified against simulations, highlighting the crucial role of magnetic shear in tilting of turbulence and generation of flow.
PHYSICS OF PLASMAS
(2022)
Article
Engineering, Environmental
Lacey A. Pyle, William C. Hockaday, Thomas Boutton, Kyriacos Zygourakis, Timothy J. Kinney, Caroline A. Masiello
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2015)
Article
Engineering, Chemical
Hao Sun, Catherine E. Brewer, Caroline A. Masiello, Kyriacos Zygourakis
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2015)
Article
Green & Sustainable Science & Technology
Catherine E. Brewer, Eric T. Hall, Klaus Schmidt-Rohr, David A. Laird, Robert C. Brown, Kyriacos Zygourakis
ENVIRONMENTAL PROGRESS & SUSTAINABLE ENERGY
(2017)
Article
Engineering, Environmental
Julia E. Vidonish, Kyriacos Zygourakis, Caroline A. Masiello, Xiaodong Gao, Jacques Mathieu, Pedro J. J. Alvarez
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2016)
Review
Engineering, Multidisciplinary
Julia E. Vidonish, Kyriacos Zygourakis, Caroline A. Masiello, Gabriel Sabadell, Pedro J. J. Alvarez
Article
Energy & Fuels
Pradeep Venkataraman, Kyriakos Zygourakis, Walter G. Chapman, Scott L. Wellington, Michael Shammai
Article
Engineering, Chemical
Julia E. Vidonish, Pedro J. J. Alvarez, Kyriacos Zygourakis
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2018)
Article
Engineering, Chemical
Kyriacos Zygourakis, Hao Sun, Pauline Markenscoff
Article
Agricultural Engineering
Catherine E. Brewer, Victoria J. Chuang, Caroline A. Masiello, Helge Gonnermann, Xiaodong Gao, Brandon Dugan, Laura E. Driver, Pietro Panzacchi, Kyriacos Zygourakis, Christian A. Davies
BIOMASS & BIOENERGY
(2014)
Article
Engineering, Environmental
Caroline A. Masiello, Ye Chen, Xiaodong Gao, Shirley Liu, Hsiao-Ying Cheng, Matthew R. Bennett, Jennifer A. Rudgers, Daniel S. Wagner, Kyriacos Zygourakis, Jonathan J. Silberg
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2013)
Article
Engineering, Chemical
Hao Sun, William C. Hockaday, Caroline A. Masiello, Kyriacos Zygourakis
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2012)
Article
Engineering, Environmental
Wen Song, Julia E. Vidonish, Roopa Kamath, Pingfeng Yu, Chun Chu, Bhagavatula Moorthy, Baoyu Gao, Kyriacos Zygourakis, Pedro J. J. Alvarez
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2019)
Article
Engineering, Chemical
Ye Gao, Kyriacos Zygourakis
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2019)
Article
Engineering, Chemical
Priscilla Dias da Silva, Samantha K. Samaniego Andrade, Kyriacos Zygourakis, Michael S. Wong
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2019)
Article
Engineering, Chemical
Kyriacos Zygourakis