Protein-protein interaction investigated by steered molecular dynamics: The TCR-pMHC complex
BIOPHYSICAL JOURNAL (2008)
期刊
BIOPHYSICAL JOURNAL
卷 95, 期 8, 页码 3575-3590出版社
CELL PRESS
关键词
类别
作者
我是这篇论文的作者
推荐
Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
Lukas Susac, Mai T. Vuong, Christoph Thomas, Soren von Bulow, Caitlin O'Brien-Ball, Ana Mafalda Santos, Ricardo A. Fernandes, Gerhard Hummer, Robert Tampe, Simon J. Davis
CELL (2022)
A dynamic biomimetic model of the membrane-bound CD4-CD3-TCR complex during pMHC disengagement
Zachary A. Rollins, Roland Faller, Steven C. George
BIOPHYSICAL JOURNAL (2023)
The Full Model of the pMHC-TCR-CD3 Complex: A Structural and Dynamical Characterization of Bound and Unbound States
Josephine Alba, Marco D'Abramo
CELLS (2022)
Conformational flexibility of a free and TCR-bound pMHC-I protein investigated by long-term molecular dynamics simulations
Lisa Tomasiak, Rudolf Karch, Wolfgang Schreiner
BMC IMMUNOLOGY (2022)
Mechanism for the Unfolding of the TOP7 Protein in Steered Molecular Dynamics Simulations as Revealed by Mutual Information Analysis
Ognjen Perisic, Willy Wriggers
FRONTIERS IN MOLECULAR BIOSCIENCES (2021)
Maturation of siRNA by strand separation: Steered molecular dynamics study
Rakesh Kumar Mishra, Sanchita Mukherjee, Dhananjay Bhattacharyya
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)
Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics
Shuting Zhang, Dimitrios Vavylonis
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2023)
Conformation-selective rather than avidity-based binding to tumor associated antigen derived peptide-MHC enables targeting of WT1-pMHC low expressing cancer cells by anti-WT1-pMHC/CD3 T cell engagers
Even Walseng, Bo Wang, Chunning Yang, Pooja Patel, Chihao Zhao, Hanzhi Zhang, Peng Zhao, Yariv Mazor
FRONTIERS IN IMMUNOLOGY (2023)
Steered Molecular Dynamics Simulations Study on FABP4 Inhibitors
Rosario Tomarchio, Vincenzo Patamia, Chiara Zagni, Letizia Crocetti, Agostino Cilibrizzi, Giuseppe Floresta, Antonio Rescifina
MOLECULES (2023)
Novel chalcones derivatives with potential antineoplastic activity investigated by docking and molecular dynamics simulations
Raimundo de A. M. Neto, Cleydson B. R. Santos, Shayanne V. C. Henriques, Leticia de O. Machado, Jorddy N. Cruz, Carlos H. T. de P. da Silva, Leonardo B. Federico, Edivaldo H. C. de Oliveira, Michel P. C. de Souza, Patricia N. B. da Silva, Carlton A. Taft, Irlon M. Ferreira, Madson R. F. Gomes
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)
Dichotomy in TCR V-domain dynamics binding the opposed inclined planes of pMHC-II and pMHC-I a-helices
Joseph S. Murray
MOLECULAR IMMUNOLOGY (2023)
Stretching effect on intrachain conformational ordering of polymers: A steered molecular dynamics simulation
Ran Chen, Chuanfu Luo
POLYMER (2022)
Effects of ultrasonic vibration on sapphire polishing investigated by molecular dynamics
Wenhu Xu, Chong Sheng, Min Zhong
TRIBOLOGY INTERNATIONAL (2022)
Filler-induced heterogeneous nucleation of polymer crystals investigated by molecular dynamics simulations
Dominic Wadkin-Snaith, Paul Mulheran, Karen Johnston
POLYMER (2023)
Using steered molecular dynamic tension for assessing quality of computational protein structure models
Lyman Monroe, Daisuke Kihara
JOURNAL OF COMPUTATIONAL CHEMISTRY (2022)
Outcome and Prognostic Factors of COVID-19 Infection in Swiss Cancer Patients: Final Results of SAKK 80/20 (CaSA)
Markus Joerger, Yannis Metaxas, Khalil Zaman, Olivier Michielin, Nicolas Mach, Adrienne Bettini, Andreas M. Schmitt, Nathan Cantoni, Clemens B. Caspar, Sonja Stettler, Roma Malval, Miklos Pless, Christian Britschgi, Christoph Renner, Dieter Koeberle, Jessica D. Schulz, Christoph Kopp, Stefanie Hayoz, Anastasios Stathis, Roger von Moos
CANCERS (2022)
Identification of New Vulnerabilities in Conjunctival Melanoma Using Image-Based High Content Drug Screening
Katya Nardou, Michael Nicolas, Fabien Kuttler, Katarina Cisarova, Elifnaz Celik, Mathieu Quinodoz, Nicolo Riggi, Olivier Michielin, Carlo Rivolta, Gerardo Turcatti, Alexandre Pierre Moulin
CANCERS (2022)
COVID-19 in patients with cancer: first report of the ESMO international registry-based, cohort study (ESMO-CoCARE)
L. Castelo-Branco, Z. Tsourti, S. Gennatas, J. Rogado, M. Sekacheva, D. Vinal, R. Lee, A. Croitoru, M. Vitorino, S. Khallaf, S. Susnjar, W. Soewoto, A. Cardena, M. Djerouni, M. Rossi, T. Alonso-Gordoa, C. Ngelangel, J. G. Whisenant, T. K. Choueiri, G. Dimopoulou, S. Pradervand, D. Arnold, K. Harrington, O. Michielin, U. Dafni, G. Pentheroudakis, S. Peters, E. Romano
ESMO OPEN (2022)
Establishment of CORONET, COVID-19 Risk in Oncology Evaluation Tool, to Identify Patients With Cancer at Low Versus High Risk of Severe Complications of COVID-19 Disease On Presentation to Hospital
Rebecca J. Lee, Oskar Wysocki, Cong Zhou, Rohan Shotton, Ann Tivey, Louise Lever, Joshua Woodcock, Laurence Albiges, Angelos Angelakas, Dirk Arnold, Theingi Aung, Kathryn Banfill, Mark Baxter, Fabrice Barlesi, Arnaud Bayle, Benjamin Besse, Talvinder Bhogal, Hayley Boyce, Fiona Britton, Antonio Calles, Luis Castelo-Branco, Ellen Copson, Adina E. Croitoru, Sourbha S. Dani, Elena Dickens, Leonie Eastlake, Paul Fitzpatrick, Stephanie Foulon, Henrik Frederiksen, Hannah Frost, Sarju Ganatra, Spyridon Gennatas, Andreas Glenthoj, Fabio Gomes, Donna M. Graham, Christina Hague, Kevin Harrington, Michelle Harrison, Laura Horsley, Richard Hoskins, Prerana Huddar, Zoe Hudson, Lasse H. Jakobsen, Nalinie Joharatnam-Hogan, Sam Khan, Umair T. Khan, Khurum Khan, Christophe Massard, Alec Maynard, Hayley McKenzie, Olivier Michielin, Anne C. Mosenthal, Berta Obispo, Rushin Patel, George Pentheroudakis, Solange Peters, Kimberly Rieger-Christ, Timothy Robinson, Jacobo Rogado, Emanuela Romano, Michael Rowe, Marina Sekacheva, Roseleen Sheehan, Julie Stevenson, Alexander Stockdale, Anne Thomas, Lance Turtle, David Vinal, Jamie Weaver, Sophie Williams, Caroline Wilson, Carlo Palmieri, Donal Landers, Timothy Cooksley, Caroline Dive, Andre Freitas, Anne C. Armstrong
JCO CLINICAL CANCER INFORMATICS (2022)
Prognosis of Patients With Primary Melanoma Stage I and II According to American Joint Committee on Cancer Version 8 Validated in Two Independent Cohorts: Implications for Adjuvant Treatment
Claus Garbe, Ulrike Keim, Teresa Amaral, Carola Berking, Thomas K. Eigentler, Lukas Flatz, Anja Gesierich, Ulrike Leiter, Rudolf Stadler, Cord Sunderkotter, Thomas Tuting, Jochen Utikal, Uwe Wollina, Lisa Zimmer, Christos C. Zouboulis, Paolo A. Ascierto, Alexander M. M. Eggermont, Jean-Jacques Grob, Axel Hauschild, Lidija Kandolf Sekulovic, Georgina Long, Jason J. Luke, Olivier Michielin, Ketty Peris, Dirk Schadendorf, John M. Kirkwood, Paul C. Lorigan
JOURNAL OF CLINICAL ONCOLOGY (2022)
Single Seminal Vesicle Metastasis From Dorsal Melanoma Detected by 18F-FDG PET/CT and Confirmed by Biopsy
Nathalie Testart Dardel, Elsa Isenborghs, Massimo Valerio, Olivier Michielin, Niklaus Schaefer
CLINICAL NUCLEAR MEDICINE (2023)
Estimated Costs of the Ipilimumab-Nivolumab Therapy and Related Adverse Events in Metastatic Melanoma
Bianca Gautron Moura, Camille L. Gerard, Nathalie Testart, Marian Caikovski, Alexandre Wicky, Veronica Aedo-Lopez, Gregoire Berthod, Krisztian Homicsko, John O. Prior, Clarisse Dromain, Lana E. Kandalaft, Michel A. Cuendet, Olivier Michielin
CANCERS (2023)
Deep and lasting response and acquired resistance to BRAFV600E targeting in a low-grade ovarian cancer patient
Sandro Anchisi, Anita Wolfer, Bettina Bisig, Edoardo Missiglia, Amine Tiab, Ehab Mohamed Kamel, Olivier Michielin, George Coukos, Krisztian Homicsko
CANCER BIOLOGY & THERAPY (2023)
Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma
Fanny Seraphine Krebs, Bianca Moura, Edoardo Missiaglia, Veronica Aedo-Lopez, Olivier Michielin, Petros Tsantoulis, Bettina Bisig, Mounir Trimech, Vincent Zoete, Krisztian Homicsko
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)
Interactive process mining of cancer treatment sequences with melanoma real-world data
Alexandre Wicky, Roberto Gatta, Sofiya Latifyan, Rita De Micheli, Camille Gerard, Sylvain Pradervand, Olivier Michielin, Michel A. Cuendet
FRONTIERS IN ONCOLOGY (2023)
Testing a Model of Care for Patients on Immune Checkpoint Inhibitors Based on Electronic Patient-Reported Outcomes: Protocol for a Randomized Phase II Controlled Trial
Andre Manuel da Silva Lopes, Sara Colomer-Lahiguera, Celia Darnac, Stellio Giacomini, Sebastien Bugeia, Garance Gutknecht, Gilliosa Spurrier-Bernard, Michel Cuendet, Fanny Muet, Veronica Aedo-Lopez, Nuria Mederos, Olivier Michielin, Alfredo Addeo, Sofiya Latifyan, Manuela Eicher
JMIR RESEARCH PROTOCOLS (2023)
A model of care using patient-reported outcomes for remotely managing symptoms of cancer patients treated with immune checkpoint inhibitors
A. Da Silva Lopes, S. Colomer-Lahiguera, C. Darnac S. Giacomini, A. Wicky, S. Bugeia, G. Gutknecht, N. Mederos Alfonso, S. Latifyan, A. Addeo, O. Michielin, M. Eicher
SWISS MEDICAL WEEKLY (2022)
Defining unique clinical hallmarks for immune checkpoint inhibitor-based therapies (vol 10, e003024, 2022)
O. Michielin, A. Lalani, C. Robert
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2022)