Expression of the ALS-Causing Variant hSOD1G93A Leads to an Impaired Integrity and Altered Regulation of Claudin-5 Expression in an in Vitro Blood–Spinal Cord Barrier Model

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

(2014) E. A. Winkler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-CNS Barrier Impairment in ALS patients versus an animal model

(2014) Svitlana Garbuzova-Davis et al.   Frontiers in Cellular Neuroscience

The changing scene of amyotrophic lateral sclerosis

(2013) Wim Robberecht et al.   NATURE REVIEWS NEUROSCIENCE

Blood–spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis

(2012) Ethan A. Winkler et al.   ACTA NEUROPATHOLOGICA

Activation of the Wnt/β-catenin signaling pathway is associated with glial proliferation in the adult spinal cord of ALS transgenic mice

(2012) Yanchun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impaired blood–brain/spinal cord barrier in ALS patients

(2012) Svitlana Garbuzova-Davis et al.   BRAIN RESEARCH

Blood–Spinal Cord Barrier Pericyte Reductions Contribute to Increased Capillary Permeability

(2012) Ethan A Winkler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions

(2011) R. S. Beard et al.   BLOOD

TNF-alpha induced NFκB signaling and p65 (RelA) overexpression repress Cldn5 promoter in mouse brain endothelial cells

(2011) Muhammad Aslam et al.   CYTOKINE

Muscle atrophy induced by SOD1G93A expression does not involve the activation of caspase in the absence of denervation

(2011) Gabriella Dobrowolny et al.   Skeletal Muscle

The neurobiology of amyotrophic lateral sclerosis

(2010) André Bento-Abreu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Vascular endothelial growth factor prevents G93A-SOD1-induced motor neuron degeneration

(2009) J. Simon Lunn et al.   Developmental Neurobiology

Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure

(2009) Feng Chen et al.   HEPATOLOGY

Wild-type Cu/Zn superoxide dismutase (SOD1) does not facilitate, but impedes the formation of protein aggregates of amyotrophic lateral sclerosis causing mutant SOD1

(2009) Heidrun Witan et al.   NEUROBIOLOGY OF DISEASE

The role of the blood–CNS barrier in CNS disorders and their treatment

(2009) Alan M. Palmer   NEUROBIOLOGY OF DISEASE

VE-cadherin and claudin-5: it takes two to tango

(2008) Julie Gavard et al.   NATURE CELL BIOLOGY

Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

(2008) Andrea Taddei et al.   NATURE CELL BIOLOGY

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

(2008) Zhihui Zhong et al.   NATURE NEUROSCIENCE

SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function

(2007) Ruud D. Fontijn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY