期刊
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
卷 19, 期 17, 页码 4988-4992出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.bmcl.2009.07.074
关键词
CCR5; 4,4-Disubstituted cyclohexylamine; Antagonists; Anti-HIV-1 agents
A series of 4,4-disubstituted cyclohexylamine based CCR5 antagonists has been designed and synthesized. Their antiviral structure-activity relationship has been extensively explored. (C) 2009 Elsevier Ltd. All rights reserved.
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